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Pharmaceutical Biology Volume 58, 2020 - Issue 1
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Article

Identification of the metabolites of isochlorogenic acid A in rats by UHPLC-Q-Exactive Orbitrap MS

Kaiyan Gonga Hunan Provincial Key Laboratory of Dong Medicine, School of Pharmaceutical Sciences, Hunan University of Medicine, Huaihua, ChinaView further author information
,
Yuan Yanga Hunan Provincial Key Laboratory of Dong Medicine, School of Pharmaceutical Sciences, Hunan University of Medicine, Huaihua, China;b Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, School of Public Health, Guizhou Medical University, Guiyang, ChinaView further author information
,
Kailin Lia Hunan Provincial Key Laboratory of Dong Medicine, School of Pharmaceutical Sciences, Hunan University of Medicine, Huaihua, ChinaView further author information
,
Lian Zhua Hunan Provincial Key Laboratory of Dong Medicine, School of Pharmaceutical Sciences, Hunan University of Medicine, Huaihua, ChinaView further author information
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Xinjun Zhia Hunan Provincial Key Laboratory of Dong Medicine, School of Pharmaceutical Sciences, Hunan University of Medicine, Huaihua, ChinaView further author information
&
Wei Caia Hunan Provincial Key Laboratory of Dong Medicine, School of Pharmaceutical Sciences, Hunan University of Medicine, Huaihua, China;c Hunan Province Key Laboratory for Antibody-Based Drug and Intelligent Delivery System, Hunan University of Medicine, Huaihua, ChinaCorrespondence[email protected]
View further author information
Pages 992-998 | Received 22 Apr 2020, Accepted 06 Sep 2020, Published online: 23 Sep 2020

References

  • Cai W, Guan Y, Zhou Y, Wang YW, Ji HP, Liu ZH. 2017. Detection and characterization of the metabolites of rutaecarpine in rats based on ultra-high-performance liquid chromatography with linear ion trap-Orbitrap mass spectrometer. Pharm Biol. 55(1):294–298.
  • Cai W, Li KL, Xiong P, Gong KY, Zhu L, Yang JB, Wu WH. 2020. A systematic strategy for rapid identification of chlorogenic acids derivatives in Duhaldea nervosa using UHPLC-Q-Exactive Orbitrap mass spectrometry. Arab J Chem. 13(2):3751–3761.
  • Clifford MN, Johnston KL, Knight S, Kuhnert N. 2003. Hierarchical scheme for LC-MSn identification of chlorogenic acids. J Agric Food Chem. 51(10):2900–2911.
  • Clifford MN, Knight S, Kuhnert N. 2005. Discriminating between the six isomers of dicaffeoylquinic acid by LC-MSn. J Agric Food Chem. 53(10):3821–3832.
  • Ferreira LLG, Andricopulo AD. 2019. ADMET modeling approaches in drug discovery. Drug Discov Today. 24(5):1157–1165.
  • Guan Y, Wang Y, Zhou Y, Wang YW, Zheng BJ, Wang LT, Cai W. 2017. Determination of isochlorogenic acid A and isochlorogenic acid C in Duhaldea nervosa by HPLC. Lishizhen J Tradit Chin Med Res. 28:1032–1034.
  • Jaiswal R, Halabi EA, Karar MG, Kuhnert N. 2014. Identification and characterisation of the phenolics of Ilex glabra L. Gray (Aquifoliaceae) leaves by liquid chromatography tandem mass spectrometry. Phytochemistry. 106:141–155.
  • Liu LH, Zhang JY, Zheng BJ, Guan Y, Wang LT, Chen L, Cai W. 2018. Rapid characterization of chlorogenic acids in Duhaldea nervosa based on ultra-high-performance liquid chromatography-linear trap quadropole-Orbitrap-mass spectrometry and mass spectral trees similarity filter technique. J Sep Sci. 41(8):1764–1774.
  • Long S. 2004. Clinical experience of “maoshoucai” for treating traumatic injury. J Med Phar Chin Min. 12:231–232.
  • Martínez-Archundia M, Bello M, Correa-Basurto J. 2018. Design of drugs by filtering through ADMET, physicochemical and ligand-target flexibility properties. Methods Mol Biol. 1824:403–416.
  • Naveed M, Hejazi V, Abbas M, Kamboh AA, Khan GJ, Shumzaid M, Ahmad F, Babazadeh D, Xia FF, Faezeh MG, Li WH, et al. 2018. Chlorogenic acid (CGA): a pharmacological review and call for further research. Biomed Pharmacother. 97:67–74.
  • Qiao X, Li R, Song W, Miao WJ, Liu J, Chen HB, Guo DA, Ye M. 2016. A targeted strategy to analyze untargeted mass spectral data: Rapid chemical profiling of Scutellaria baicalensis using ultra-high performance liquid chromatography coupled with hybrid quadrupole orbitrap mass spectrometry and key ion filtering. J Chromatogr A. 1441:83–95.
  • Wang J, Cao G, Wang H, Ye H, Zhong Y, Wang G, Hao H. 2017. Characterization of isochlorogenic acid A metabolites in rats using high-performance liquid chromatography quadrupole time-of-flight mass spectrometry. Biomed Chromatogr. 31(8):e3927.
  • Wang Q, Xiao L. 2019. Isochlorogenic acid A attenuates acute lung injury induced by LPS via Nf-κB/NLRP3 signaling pathway. Am J Transl Res. 11(11):7018–7026.
  • Xiao CW. 1997. Textual research of Dong medicine and a famous doctor for treating traumatic injury. Chin. J. Ethnomed. Ethnopharm. 5:41–42.
  • Xiao CW. 2004. Explore secret of dong medicine. Changsha (China): Yuelu Press. p. 46.
  • Yang B, Meng ZY, Dong JX, Yan LP, Zou LB, Tang ZM, Dou GF. 2005. Metabolic profile of 1,5-dicaffeoylquinic acid in rats, an in vivo and in vitro study. Drug Metab Dispos. 33(7):930–936.

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