Tanshinone IIA alleviates ovalbumin-induced allergic rhinitis symptoms by inhibiting Th2 cytokine production and mast cell histamine release in mice

References

• Bayar Muluk N, Bafaqeeh SA, Cingi C. 2019. Anti-IgE treatment in allergic rhinitis. Int J Pediatr Otorhinolaryngol. 127:109674.
   PubMed Web of Science ®Google Scholar
• Bernstein DI, Schwartz G, Bernstein JA. 2016. Allergic rhinitis: mechanisms and treatment. Immunol Allergy Clin North Am. 36(2):261–278.
   PubMed Web of Science ®Google Scholar
• Bousquet J, Hellings PW, Agache I, Amat F, Annesi-Maesano I, Ansotegui IJ, Anto JM, Bachert C, Bateman ED, Bedbrook A, et al. 2019. Allergic rhinitis and its impact on asthma (ARIA) phase 4 (2018): change management in allergic rhinitis and asthma multimorbidity using mobile technology. J Allergy Clin Immunol. 143(3):864–879.
   PubMed Web of Science ®Google Scholar
• Bousquet J, Schunemann HJ, Samolinski B, Demoly P, Baena-Cagnani CE, Bachert C, Bonini S, Boulet LP, Bousquet PJ, Brozek JL, et al. 2012. Allergic rhinitis and its impact on asthma (ARIA): achievements in 10 years and future needs. J Allergy Clin Immunol. 130(5):1049–1062.
   PubMed Web of Science ®Google Scholar
• Broide DH. 2010. Allergic rhinitis: pathophysiology. Allergy Asthma Proc. 31(5):370–374.
   PubMed Web of Science ®Google Scholar
• Bui TT, Piao CH, Hyeon E, Fan Y, Van Nguyen T, Jung SY, Choi DW, Lee SY, Shin HS, Song CH, et al. 2019. The protective role of Piper nigrum fruit extract in an ovalbumin-induced allergic rhinitis by targeting of NFκBp65 and STAT3 signalings. Biomed Pharmacother. 109:1915–1923.
   PubMed Web of Science ®Google Scholar
• Bui TT, Piao CH, Song CH, Chai OH. 2017. Skullcapflavone II attenuates ovalbumin-induced allergic rhinitis through the blocking of th2 cytokine production and mast cell histamine release. Int Immunopharmacol. 52:77–84.
   PubMed Web of Science ®Google Scholar
• Cheng W, Xiang W, Wang S, Xu K. 2019. Tanshinone IIA ameliorates oxaliplatin-induced neurotoxicity via mitochondrial protection and autophagy promotion. Am J Transl Res. 11(5):3140–3149.
   PubMed Web of Science ®Google Scholar
• Cobanoğlu B, Toskala E, Ural A, Cingi C. 2013. Role of leukotriene antagonists and antihistamines in the treatment of allergic rhinitis. Curr Allergy Asthma Rep. 13(2):203–208.
   PubMed Web of Science ®Google Scholar
• Eifan AO, Durham SR. 2016. Pathogenesis of rhinitis. Clin Exp Allergy. 46(9):1139–1151.
   PubMed Web of Science ®Google Scholar
• Eiringhaus K, Renz H, Matricardi P, Skevaki C. 2019. Component-resolved diagnosis in allergic rhinitis and asthma. J Appl Lab Med. 3(5):883–898.
   PubMedGoogle Scholar
• Fan GW, Gao XM, Wang H, Zhu Y, Zhang J, Hu LM, Su YF, Kang LY, Zhang BL. 2009. The anti-inflammatory activities of tanshinone IIA, an active component of TCM, are mediated by estrogen receptor activation and inhibition of iNOS. J Steroid Biochem Mol Biol. 113(3–5):275–280.
   PubMed Web of Science ®Google Scholar
• Fan XH, Cheng L, Yan AH. 2019. Ameliorative effect of acetylshikonin on ovalbumin (ova)-induced allergic rhinitis in mice through the inhibition of Th2 cytokine production and mast cell histamine release. APMIS. 127(10):688–695.
   PubMed Web of Science ®Google Scholar
• Gao X, Li N, Zhang JS, He F. 2017. The comparation of establishing the allergic rhinitis model between Kunming mice and BALB/c mice. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 52:501–505.
   PubMedGoogle Scholar
• Gu Y, Liang Z, Wang H, Jin J, Zhang S, Xue S, Chen J, He H, Duan K, Wang J, et al. 2016. Tanshinone IIA protects H9c2 cells from oxidative stress-induced cell death via microrna-133 upregulation and Akt activation. Exp Ther Med. 12(2):1147–1152.
   PubMed Web of Science ®Google Scholar
• Hoyte FCL, Nelson HS. 2018. Recent advances in allergic rhinitis. F1000Res. 7:1333.
   Google Scholar
• Jia MH, Chen XY, Zhang Y, Liao ZS. 2017. Effect of nasal glucocorticoid combined with loratadine or montelukast on allergic rhinitis. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 31:369–373.
   PubMedGoogle Scholar
• Kawauchi H, Yanai K, Wang DY, Itahashi K, Okubo K. 2019. Antihistamines for allergic rhinitis treatment from the viewpoint of nonsedative properties. Int J Mol Sci. 20(1):213.
   PubMed Web of Science ®Google Scholar
• Kim HI, Kim JK, Kim JY, Han MJ, Kim DH. 2019. Fermented red ginseng and ginsenoside Rd alleviate ovalbumin-induced allergic rhinitis in mice by suppressing IgE, interleukin-4, and interleukin-5 expression. J Ginseng Res. 43(4):635–644.
   PubMed Web of Science ®Google Scholar
• Lee HJ, Kim B, Im NR, Lee DY, Kim HK, Lee SH, Lee HM, Lee SH, Baek SK, Kim TH. 2016. Decreased expression of E-cadherin and ZO-1 in the nasal mucosa of patients with allergic rhinitis: altered regulation of E-cadherin by IL-4, IL-5, and TNF-alpha. Am J Rhinol Allergy. 30(3):173–178.
   PubMed Web of Science ®Google Scholar
• Li C, Han X, Zhang H, Wu J, Li B. 2016. The interplay between autophagy and apoptosis induced by tanshinone IIA in prostate cancer cells. Tumour Biol. 37(6):7667–7674.
   PubMedGoogle Scholar
• Li N, Yang L, Zhang B, Chen S. 2018. Tanshinone IIA effects on ovarian cancer cell line. J Pharm Pharmacol. 70(10):1369–1377.
   PubMed Web of Science ®Google Scholar
• Li Q, Qin GZ, Gu X, Wang YP, Zhang LZ, You CP, Zhang ML, Sun H. 2018. Effects of sil-13r-alpha2 on the nasal mucosa goblet cell apoptosis of allergic rhinitis of rats. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 53:745–750.
   PubMedGoogle Scholar
• Li Q, Shen L, Wang Z, Jiang HP, Liu LX. 2016. Tanshinone IIA protects against myocardial ischemia reperfusion injury by activating the PI3K/Akt/mTOR signaling pathway. Biomed Pharmacother. 84:106–114.
   PubMed Web of Science ®Google Scholar
• Li X, Park SJ, Jin F, Deng Y, Yang JH, Chang JH, Kim DY, Kim JA, Lee YJ, Murakami M, et al. 2018. Tanshinone IIA suppresses FcεRI-mediated mast cell signaling and anaphylaxis by activation of the Sirt1/LKB1/AMPK pathway. Biochem Pharmacol. 152:362–372.
   PubMed Web of Science ®Google Scholar
• Liang KL, Yu SJ, Huang WC, Hr Y. 2020. Luteolin attenuates allergic nasal inflammation via inhibition of interleukin-4 in an allergic rhinitis mouse model and peripheral blood from human subjects with allergic rhinitis. Front Pharmacol. 11:291.
   PubMed Web of Science ®Google Scholar
• Liu HC, Liao Y, Liu CQ. 2018. MiR-487b mitigates allergic rhinitis through inhibition of the IL-33/st2 signaling pathway. Eur Rev Med Pharmacol Sci. 22(23):8076–8083.
   PubMed Web of Science ®Google Scholar
• Mandhane SN, Shah JH, Thennati R. 2011. Allergic rhinitis: an update on disease, present treatments and future prospects. Int Immunopharmacol. 11(11):1646–1662.
   PubMed Web of Science ®Google Scholar
• Moon PD, Han NR, Lee JS, Kim HY, Hong S, Kim HJ, Yoo MS, Kim HM, Jeong HJ. 2018. β-Eudesmol inhibits thymic stromal lymphopoietin through blockade of caspase-1/NF-κB signal cascade in allergic rhinitis murine model. Chem Biol Interact. 294:101–106.
   PubMed Web of Science ®Google Scholar
• Mygind N. 2014. Allergic rhinitis. Chem Immunol Allergy. 100:62–68.
   PubMedGoogle Scholar
• Pawankar R, Mori S, Ozu C, Kimura S. 2011. Overview on the pathomechanisms of allergic rhinitis. Asia Pac Allergy. 1(3):157–167.
   PubMedGoogle Scholar
• Price D, Klimek L, Galffy G, Emmeluth M, Koltun A, Kopietz F, Nguyen DT, van Weissenbruch R, Pohl W, Kuhl HC, et al. 2020. Allergic rhinitis and asthma symptoms in a real-life study of MP-AzeFlu to treat multimorbid allergic rhinitis and asthma. Clin Mol Allergy. 18:15.
   PubMedGoogle Scholar
• Ricketti PA, Alandijani S, Lin CH, Casale TB. 2017. Investigational new drugs for allergic rhinitis. Expert Opin Investig Drugs. 26(3):279–292.
   PubMed Web of Science ®Google Scholar
• Sagit M, Polat H, Gurgen SG, Berk E, Guler S, Yasar M. 2017. Effectiveness of quercetin in an experimental rat model of allergic rhinitis. Eur Arch Otorhinolaryngol. 274(8):3087–3095.
   PubMed Web of Science ®Google Scholar
• Suzuki M, Yokota M, Nakamura Y, Ozaki S, Murakami S. 2017. Intranasal administration of il-35 inhibits allergic responses and symptoms in mice with allergic rhinitis. Allergol Int. 66(2):351–356.
   PubMed Web of Science ®Google Scholar
• Taylor-Clark T. 2010. Histamine in allergic rhinitis. Adv Exp Med Biol. 709:33–41.
   PubMed Web of Science ®Google Scholar
• Wise SK, Lin SY, Toskala E, Orlandi RR, Akdis CA, Alt JA, Azar A, Baroody FM, Bachert C, Canonica GW, et al. 2018. International consensus statement on allergy and rhinology: allergic rhinitis—executive summary. Int Forum Allergy Rhinol. 8(2):85–352.
   PubMed Web of Science ®Google Scholar
• Won Jung H, Jung JK, Weon Cho C, Kang JS, Park YK. 2012. Antiallergic effect of KOB03, a polyherbal medicine, on mast cell-mediated allergic responses in ovalbumin-induced allergic rhinitis mouse and human mast cells. J Ethnopharmacol. 142(3):684–693.
   PubMed Web of Science ®Google Scholar
• Xu F, Yu S, Qin M, Mao Y, Jin L, Che N, Liu S, Ge R. 2018. Hydrogen-rich saline ameliorates allergic rhinitis by reversing the imbalance of Th1/Th2 and up-regulation of CD4 + CD25 + Foxp3 + regulatory T cells, interleukin-10, and membrane-bound transforming growth factor-β in guinea pigs. Inflammation. 41(1):81–92.
   PubMed Web of Science ®Google Scholar
• Xu M, Cao FL, Zhang YF, Shan L, Jiang XL, An XJ, Xu W, Liu XZ, Wang XY. 2015. Tanshinone IIA therapeutically reduces LPS-induced acute lung injury by inhibiting inflammation and apoptosis in mice. Acta Pharmacol Sin. 36(2):179–187.
   PubMed Web of Science ®Google Scholar
• Zhang T, Finn DF, Barlow JW, Walsh JJ. 2016. Mast cell stabilisers. Eur J Pharmacol. 778:158–168.
   PubMed Web of Science ®Google Scholar