Cardiac and systemic haemodynamic complications of liver cirrhosis

References

• Jepsen P, Vilstrup H, Andersen PK, Lash TL, Sørensen HT. Comorbidity and survival of Danish cirrhosis patients: A nationwide population-based cohort study. Hepatology. 2008; 48: 214–20
   PubMed Web of Science ®Google Scholar
• Henriksen JH, Siemssen O, Krintel JJ, Malchow-Møller A, Bendtsen F, Ring-Larsen H. Dynamics of albumin in plasma and ascitic fluid in patients with cirrhosis. J Hepatol. 2001; 34: 53–60
   PubMed Web of Science ®Google Scholar
• Sort P, Navasa M, Arroyo V, Aldeguer X, Planas R, Ruiz-del-Arbol L, et al. Effect of intravenous albumin on renal impairment and mortality in patients with cirrhosis and spontaneous bacterial peritonitis. N Engl J Med. 1999; 341: 403–9
   PubMed Web of Science ®Google Scholar
• Keiding S, Sørensen M, Bender D, Munk OL, Ott P, Vilstrup H. Brain metabolism of 13N-ammonia during acute hepatic encephalopathy in cirrhosis measured by positron emission tomography. Hepatology. 2006; 43: 42–50
   PubMed Web of Science ®Google Scholar
• La Villa G, Gentilini P. Hemodynamic alterations in liver cirrhosis. Mol Aspects Med. 2008; 29: 112–8
   PubMed Web of Science ®Google Scholar
• Cárdenas A, Ginès P. Predicting mortality in cirrhosis. Serum sodium helps. N Engl J Med. 2008; 359: 1060–2
   PubMed Web of Science ®Google Scholar
• Henriksen JH, Bendtsen F, Møller S. Normal red cell cardiac output in the hyperkinetic syndrome of alcoholic cirrhosis. J Hepatol. 2001; 34: 782–3
   PubMed Web of Science ®Google Scholar
• Kowalski HJ, Abelmann WH. The cardiac output in Laennec's cirrhosis. J Clin Invest. 1953; 32: 1025–33
   PubMed Web of Science ®Google Scholar
• Schrier RW, Arroyo V, Bernardi M, Epstein M, Henriksen JH, Rodés J. Peripheral arterial vasodilation hypothesis: A proposal for the initiation of renal sodium and water retention in cirrhosis. Hepatology. 1988; 8: 1151–7
   PubMed Web of Science ®Google Scholar
• Møller S, Henriksen JH. The systemic circulation in cirrhosis. Ascites and renal dysfunction in liver disease, P Gines, V Arroyo, J Rodes, RW Schrier. Blackwell, Malden 2005; 139–155
   Google Scholar
• Møller, S, Henriksen, JH, Bendtsen, F. Pathogenetic background for treatment of ascites and hepatorenal syndrome. Hepatol Int. 2008;2:416–28.
   PubMed Web of Science ®Google Scholar
• Møller S, Henriksen JH. Cardiovascular complications of cirrhosis. Gut. 2008; 57: 268–78
   PubMed Web of Science ®Google Scholar
• Caraceni P, Dazzani F, Salizzoni E, Domenicali M, Zambruni A, Trevisani F, et al. Muscle circulation contributes to hyperdynamic circulatory syndrome in advanced cirrhosis. Hepatology. 2008; 48: 559–66
   Web of Science ®Google Scholar
• Møller S, Henriksen JH, Bendtsen F. Central and noncentral blood volumes in cirrhosis: Relationship to anthropometrics and gender. Am J Physiol Gastrointest Liver Physiol. 2003; 284: G970–9
   PubMed Web of Science ®Google Scholar
• Møller S, Bendtsen F, Henriksen JH. Effect of volume expansion on systemic hemodynamics and central and arterial blood volume in cirrhosis. Gastroenterology. 1995; 109: 1917–25
   PubMed Web of Science ®Google Scholar
• Colombato LA, Albillos A, Groszmann RJ. The role of central blood volume in the development of sodium retention in portal hypertensive rats. Gastroenterology. 1996; 110: 193–8
   PubMed Web of Science ®Google Scholar
• Henriksen JH, Møller S, Schifter S, Abrahamsen J, Becker U. High arterial compliance in cirrhosis is related to low adrenaline and elevated circulating calcitonin gene-related peptide but not to activated vasoconstrictor systems. Gut. 2001; 49: 112–8
   PubMed Web of Science ®Google Scholar
• Andreu V, Perello A, Moitinho E, Escorseli A, Garcia-Pagán JC, Bosch J, et al. Total effective vascular compliance in patients with cirrhosis. Effects of propranolol. J Hepatol. 2002; 36: 356–61
   PubMed Web of Science ®Google Scholar
• Henriksen JH, Fuglsang S, Bendtsen F, Christensen E, Møller S. Arterial compliance in patients with cirrhosis. Am J Physiol Gastrointest Liver Physiol. 2001; 280: G584–94
   PubMed Web of Science ®Google Scholar
• Wang YX, Fitch RM. Vascular stiffness: Measurements, mechanisms and implications. Curr Vasc Pharmacol. 2004; 2: 379–84
   PubMedGoogle Scholar
• Balmain S, Padmanabhan N, Ferrell WR, Morton JJ, McMurray JJ. Differences in arterial compliance, microvascular function and venous capacitance between patients with heart failure and either preserved or reduced left ventricular systolic function. Eur J Heart Fail. 2007; 9: 865–71
   PubMed Web of Science ®Google Scholar
• Shapiro BP, Lam CS, Patel JB, Mohammed SF, Kruger M, Meyer DM, et al. Acute and chronic ventricular-arterial coupling in systole and diastole: Insights from an elderly hypertensive model. Hypertension. 2007; 50: 503–11
   PubMed Web of Science ®Google Scholar
• Hansen TW, Jeppesen P, Torp-Pedersen C. Prognostic significance of aortic pulse-wave velocity. Vascular hemodynamics. Bioengineering and clinical perspectives, PJ Yim. Hoboken, New Jersey: Wiley-Blackwell. 2008; 85–94
   Google Scholar
• Mahmud A, Feely J. Arterial stiffness and the renin-angiotensin-aldosterone system. JRAAS. 2004; 5: 102–8
   Google Scholar
• Møller S, Bendtsen F, Henriksen JH. Determinants of the renin-angiotensin-aldosterone system in cirrhosis with special emphasis on the central blood volume. Scand J Gastroenterol. 2006; 41: 4518
   Google Scholar
• Arroyo V, Terra C, Ginès P. Advances in the pathogenesis and treatment of type-1 and type-2 hepatorenal syndrome. J Hepatol. 2007; 46: 935–46
   PubMed Web of Science ®Google Scholar
• Møller S, Wiinberg N, Henriksen J H. Noninvasive 24-hour ambulatory arterial blood pressure monitoring in cirrhosis. Hepatology. 1995; 22: 88–95
   PubMed Web of Science ®Google Scholar
• Møller S, Iversen JS, Henriksen JH, Bendtsen F. Reduced baroreceptor reflex sensitivity in alcoholic cirrhosis. Relations to haemodynamic and humoral systems. Am J Physiol. 2007; 292: H2966–72
   PubMed Web of Science ®Google Scholar
• Wiest R, Groszmann R J. The paradox of nitric oxide in cirrhsois and portal hypertension: Too much, not enough. Hepatology. 2002; 35: 478–91
   PubMed Web of Science ®Google Scholar
• Iwakiri Y, Groszmann R J. The hyperdynamic circulation of chronic liver diseases: From the patient to the molecule. Hepatology. 2006; 43: 121–31
   PubMed Web of Science ®Google Scholar
• Ebrahimkhani MR, Mani AR, Moore K. Hydrogen sulphide and the hyperdynamic circulation in cirrhosis: A hypothesis. Gut. 2005; 54: 1668–71
   PubMed Web of Science ®Google Scholar
• Hennenberg M, Biecker E, Trebicka J, Jochem K, Zhou Q, Schmidt M, et al. Defective RhoA/Rho-kinase signaling contributes to vascular hypocontractility and vasodilation in cirrhotic rats. Gastroenterology. 2006; 130: 838–54
   PubMed Web of Science ®Google Scholar
• Schrier R W. Water and sodium retention in edematous disorders: Role of vasopressin and aldosterone. Am J Med. 2006; 119: 1917–25
   Google Scholar
• Wiest R, Jurzik L, Herold T, Straub RH, Schölmerich J. Role of NPY for vasoregulation in the splanchnic circulation during portal hypertension. Peptides. 2007; 28: 396–404
   PubMed Web of Science ®Google Scholar
• Abraldes JG, Iwakiri Y, Loureiro-Silva M, Haq O, Sessa WC, Groszmann R J. Mild increases in portal pressure upregulate vascular endothelial growth factor and endothelial nitric oxide synthase in the intestinal microcirculatory bed, leading to a hyperdynamic state. Am J Physiol Gastrointest Liver Physiol. 2006; 290: G980–7
   PubMed Web of Science ®Google Scholar
• Arroyo V, Terra C, Gines P. Advances in the pathogenesis and treatment of type-1 and type-2 hepatorenal syndrome. J Hepatol. 2007; 46: 935–46
   PubMed Web of Science ®Google Scholar
• Salerno F, Gerbes A, Gines P, Wong F, Arroyo V. Diagnosis, prevention and treatment of the hepatorenal syndrome in cirrhosis. A consensus workshop of the International Ascites Club. Gut. 2007; 56: 1310–8
   PubMed Web of Science ®Google Scholar
• Helmy A, Newby DE, Jalan R, Hayes PC, Webb D J. Enhanced vasodilatation to endothelin antagonism in patients with compensated cirrhosis and the role of nitric oxide. Gut. 2003; 52: 410–5
   PubMed Web of Science ®Google Scholar
• Langer DA, Shah V H. Nitric oxide and portal hypertension: Interface of vasoreactivity and angiogenesis. J Hepatol. 2006; 44: 209–16
   PubMed Web of Science ®Google Scholar
• Ferguson JW, Dover AR, Chia S, Cruden NL, Hayes PC, Newby D E. Inducible nitric oxide synthase activity contributes to the regulation of peripheral vascular tone in patients with cirrhosis and ascites. Gut. 2005; 55: 542–6
   PubMed Web of Science ®Google Scholar
• Fernandez M, Mejias M, Angermayr B, Garcia-Pagan JC, Rodés J, Bosch J. Inhibition of VEGF receptor-2 decreases the development of hyperdynamic splanchnic circulation and portal-systemic collateral vessels in portal hypertensive rats. J Hepatol. 2005; 43: 98–103
   PubMed Web of Science ®Google Scholar
• Bolognesi M, Sacerdoti D, Di Pascoli M, Angeli P, Quarta S, Sticca A, et al. Haeme oxygenase mediates hyporeactivity to phenylephrine in the mesenteric vessels of cirrhotic rats with ascites. Gut. 2005; 54: 1630–6
   PubMed Web of Science ®Google Scholar
• Hendrickse MT, Triger D R. Vagal dysfunction and impaired urinary sodium and water excretion in cirrhosis. Am J Gastroenterol. 1994; 89: 750–7
   PubMed Web of Science ®Google Scholar
• Hansen S, Møller S, Bendtsen F, Jensen G, Henriksen J H. Diurnal variation and dispersion in Q-T interval in cirrhosis. Relation to haemodynamic changes. J Hepatol. 2007; 47: 373–80
   PubMed Web of Science ®Google Scholar
• Møller S, Henriksen J H. Cardiovascular dysfunction in cirrhosis. Patophysiological evidence of a cirrhotic cardiomyopathy. Scand J Gastroenterol. 2001; 36: 785–94
   PubMed Web of Science ®Google Scholar
• Ma Z, Lee S S. Cirrhotic cardiomyopathy: Getting to the heart of the matter. Hepatology. 1996; 24: 451–9
   PubMed Web of Science ®Google Scholar
• Cazzaniga M, Salerno F, Pagnozzi G, Dionigi E, Visentin S, Cirello I, et al. Diastolic dysfunction is associated with poor survival in patients with cirrhosis with transjugular intrahepatic portosystemic shunt. Gut. 2007; 56: 869–75
   PubMed Web of Science ®Google Scholar
• Møller S, Henriksen J H. Cirrhotic cardiomyopathy: A pathophysiological review of circulatory dysfunction in liver disease. Heart. 2002; 87: 9–15
   PubMed Web of Science ®Google Scholar
• Møller S, Søndergaard L, Møgelvang J, Henriksen O, Henriksen J H. Decreased right heart blood volume determined by magnetic resonance imaging: Evidence of central underfilling in cirrhosis. Hepatology. 1995; 22: 472–8
   PubMed Web of Science ®Google Scholar
• Grose RD, Nolan J, Dillon JF, Errington M, Hannan WJ, Bouchier IA, et al. Exercise-induced left ventricular dysfunction in alcoholic and non-alcoholic cirrhosis. J Hepatol. 1995; 22: 326–32
   PubMed Web of Science ®Google Scholar
• Pacher P, Batkai S, Kunos G. Cirrhotic cardiomyopathy:an endocannabinoid connection?. Br J Pharmacol. 2005; 146: 313–4
   PubMed Web of Science ®Google Scholar
• Myers RP, Lee S S. Cirrhotic cardiomyopathy and liver transplantation. Liver Transpl. 2000; 6: 44–52
   PubMed Web of Science ®Google Scholar
• Krag A, Bendtsen F, Henriksen JH, Møller S. Cardiac effects of terlipressin in cirrhosis. Unmasking a cirrhotic cardiomyopathy. J Hepatol. 2007; 46: 96
   Google Scholar
• Mohamed R, Forsey PR, Davies MK, Neuberger J M. Effect of liver transplantation on Q-T interval prolongation and autonomic dysfunction in end-stage liver disease. Hepatology. 1996; 23: 1128–34
   PubMed Web of Science ®Google Scholar
• Liu H, Gaskari S, Lee S S. Cardiac and vascular changes in cirrhosis: Pathogenic mechanisms. World J Gastroenterol. 2006; 12: 837–42
   PubMed Web of Science ®Google Scholar
• Henriksen JH, Fuglsang S, Bendtsen F, Christensen E, Møller S. Dyssynchronous electrical and mechanical systole in patients with cirrhosis. J Hepatol. 2002; 36: 513–20
   PubMed Web of Science ®Google Scholar
• Zambruni A, Trevisani F, Caraceni P, Bernardi M. Cardiac electrophysiological abnormalities in patients with cirrhosis. J Hepatol. 2006; 44: 994–1002
   PubMed Web of Science ®Google Scholar
• Henriksen JH, Bendtsen F, Hansen EF, Møller S. Acute non-selective -adrenergic blockade reduces prolonged frequency-adjusted Q–T interval (QTc) in patients with cirrhosis. J Hepatol. 2004; 40: 239–46
   PubMed Web of Science ®Google Scholar
• Zambruni A, Trevisani F, Di Micoli A, Savelli F, Berzigotti A, Bracci E, et al. Effect of chronic beta-blockade on QT interval in patients with liver cirrhosis. J Hepatol. 2008; 48: 415–21
   PubMed Web of Science ®Google Scholar
• Bernardi M, Calandra S, Colantoni S, Trevisani F, Raimondo ML, Sica G, et al. Q-T interval prolongation in cirrhosis: Prevalence, relationship with severity, and etiology of the disease and possible pathogenetic factors. Hepotology. 1998; 27: 28–34
   PubMed Web of Science ®Google Scholar
• Henriksen JH, Gøtze JP, Fuglsang S, Christensen E, Bendtsen F, Møller S. Increased circulating pro-brain natriuretic peptide (proBNP) and brain natriuretic peptide (BNP) in patients with cirrhosis: relation to cardiovascular dysfunction and severity of disease. Gut. 2003; 52: 1511–7
   PubMed Web of Science ®Google Scholar
• Krag A, Bendtsen F, Henriksen JH, Møller S. Low cardiac index predicts survival and renal failure in patients with ascites. Evidence of a heart-kidney axis in cirrhosis. J Hepatol. 2008; 48(Suppl 2)s118
   Google Scholar