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Scandinavian Cardiovascular Journal Volume 52, 2018 - Issue 6
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Articles

Role of pannexin and adenosine triphosphate (ATP) following myocardial ischemia/reperfusion

Sarah Brøgger KristiansenDepartment of Clinical Experimental Research, Glostrup Research Institute, Copenhagen University Hospital, Rigshospitalet-Glostrup, Glostrup, Denmark; ;Department of Drug Design and Pharmacology, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark; View further author information
,
Gry Freja SkovstedDepartment of Clinical Experimental Research, Glostrup Research Institute, Copenhagen University Hospital, Rigshospitalet-Glostrup, Glostrup, Denmark; ;Experimental Pharmacology and Toxicology, Section of Experimental Animal Models, Department of Veterinary and Animal Sciences, University of Copenhagen, Copenhagen, Denmark; View further author information
,
Lukas Adrian BerchtoldDepartment of Pediatrics, Glostrup Research Institute, Copenhagen University Hospital, Glostrup, Denmark; ;Center for Genomic Medicine, Copenhagen University Hospital, Glostrup, DenmarkView further author information
,
Aneta Radziwon-BalickaDepartment of Clinical Experimental Research, Glostrup Research Institute, Copenhagen University Hospital, Rigshospitalet-Glostrup, Glostrup, Denmark; View further author information
,
Karin DreisigDepartment of Clinical Experimental Research, Glostrup Research Institute, Copenhagen University Hospital, Rigshospitalet-Glostrup, Glostrup, Denmark; View further author information
,
Lars EdvinssonDepartment of Clinical Experimental Research, Glostrup Research Institute, Copenhagen University Hospital, Rigshospitalet-Glostrup, Glostrup, Denmark; View further author information
,
Majid SheykhzadeDepartment of Drug Design and Pharmacology, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark; View further author information
&
Kristian Agmund HaanesDepartment of Clinical Experimental Research, Glostrup Research Institute, Copenhagen University Hospital, Rigshospitalet-Glostrup, Glostrup, Denmark; Correspondence[email protected]
ORCID Iconhttp://orcid.org/0000-0001-5182-8957View further author information
ORCID Icon show all
Pages 340-343 | Received 09 Apr 2018, Accepted 17 Nov 2018, Published online: 07 Jan 2019

References

  • Dong F, Yang XJ, Jiang TB, et al. Ischemia triggered ATP release through Pannexin-1 channel by myocardial cells activates sympathetic fibers. Microvasc Res. 2016;104:32–37.
  • Vessey DA, Li L, Kelley M. P2X7 receptor agonists pre- and postcondition the heart against ischemia-reperfusion injury by opening pannexin-1/P2X7 channels. Am J Physiol Heart Circ Physiol. 2011;301:H881–H887.
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  • Kristiansen SB, Haanes KA, Sheykhzade M, et al. Endothelin receptor mediated Ca2+ signaling in coronary arteries after experimentally induced ischemia/reperfusion injury in rat. J Mol Cell Cardiol. 2017;111:1–9.
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  • Bargiotas P, Krenz A, Hormuzdi SG, et al. Pannexins in ischemia-induced neurodegeneration. Proc Natl Acad Sci USA. 2011;108:20772–20777.
  • Tonnessen T, Christensen G, Oie E, et al. Increased cardiac expression of endothelin-1 mRNA in ischemic heart failure in rats. Cardiovasc Res. 1997;33:601–610.
  • Skovsted GF, Kruse LS, Berchtold LA, et al. Myocardial ischemia-reperfusion enhances transcriptional expression of endothelin-1 and vasoconstrictor ETB receptors via the protein kinase MEK-ERK1/2 signaling pathway in rat. PLoS One. 2017;12:e0174119
  • Cohen R, Shainberg A, Hochhauser E, et al. UTP reduces infarct size and improves mice heart function after myocardial infarct via P2Y2 receptor. Biochem Pharmacol. 2011;82:1126–1133.

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