Suppression of glucose-6-phosphate-isomerase induced arthritis by oral administration of transgenic rice seeds expressing altered peptide ligands of glucose-6-phosphate-isomerase

References

• Zizzo G, De Santis M, Bosello SL, Fedele AL, Peluso G, Ferraccioli G, et al. Synovial fluid-derived T helper 17 cells correlate with inflammatory activity in arthritis, irrespectively of diagnosis. Clin Immunol. 2011;138:107–16.
   PubMed Web of Science ®Google Scholar
• Iwanami K, Matsumoto I, Tanaka Y, Inoue A, Goto D, Sumida T, et al. Arthritogenic T cell epitope in glucose-6-phosphate isomerase-induced arthritis. Arthritis Res Ther. 2008;10:R130.
   PubMed Web of Science ®Google Scholar
• Iwanami K, Matsumoto I, Tanaka-Watanabe Y, Inoue A, Mihara M, Sumida T, et al. Crucial role of the interleukin-6/interleukin-17 cytokine axis in the induction of arthritis by glucose-6-phosphate isomerase. Arthritis Rheum. 2008;58:754–63.
   PubMed Web of Science ®Google Scholar
• Koenders MI, Lubberts E, Oppers-Walgreen B, van den Bersselaar L, Helsen MM, van den Berg WB, et al. Blocking of interleukin-17 during reactivation of experimental arthritis prevents joint inflammation and bone erosion by decreasing RANKL and interleukin-1. Am J Pathol. 2005;167:141–9.
   PubMed Web of Science ®Google Scholar
• Iwanami K, Matsumoto I, Yoshiga Y, Inoue A, Kondo Y, Sumida T, et al. Altered peptide ligands inhibit arthritis induced by glucose-6-phosphate isomerase peptide. Arthritis Res Ther. 2009;11:R167.
   PubMed Web of Science ®Google Scholar
• Iizuka M, Wakasa Y, Tsuboi H, Asashima H, Hirota T, Sumida T, et al. Suppression of collagen-induced arthritis by oral administration of transgenic rice seeds expressing altered peptide ligands of type II collagen. Plant Biotechnol J. 2014;12:1143–52.
   PubMed Web of Science ®Google Scholar
• Iizuka M, Wakasa Y, Tsuboi H, Asashima H, Sumida T, Takaiwa F, et al. Prophylactic effect of the oral administration of transgenic rice seeds containing altered peptide ligands of type II collagen on rheumatoid arthritis. Biosci Biotechnol Biochem. 2014;78:1662–8.
   PubMed Web of Science ®Google Scholar
• Asashima H, Tsuboi H, Takahashi H, Hirota T, Iizuka M, Sumida T, et al. The anergy induction of M3 muscarinic acetylcholine receptor–reactive CD4+ T cells suppresses experimental sialadenitis-like Sjögren's syndrome. Arthritis Rheumatol. 2015;67:2213–25.
   PubMed Web of Science ®Google Scholar
• Wang Y, Zhu S, Liu S, Jiang L, Chen L, Wan J, et al. The vacuolar processing enzyme OsVPE1 is required for efficient glutelin processing in rice. Plant J. 2009;58:606–17.
   PubMed Web of Science ®Google Scholar
• Park JE, Cullins D, Zalduondo L, Barnett SL, Yi AK, Myers LK, et al. Molecular basis for T cell response induced by altered peptide ligand of type II collagen. J Biol Chem. 2012;287:19765–74.
   PubMed Web of Science ®Google Scholar
• Wakamatsu E, Matsumoto I, Yoshiga Y, Hayashi T, Goto D, Sumida T, et al. Altered peptide ligands regulate type II collagen-induced arthritis in mice. Mod Rheumatol. 2009;19:366–71.
   PubMed Web of Science ®Google Scholar
• Takaiwa F, Wakasa Y, Takagi H, Hiroi T. Rice seed for delivery of vaccines to gut mucosal immune tissues. Plant Biotechnol J. 2015;13:1041–55.
   PubMed Web of Science ®Google Scholar
• Li Z, Li D, Tsun A, Li B. FOXP3+ regulatory T cells and their functional regulation. Cell Mol Immunol. 2015;12:558–65.
   PubMed Web of Science ®Google Scholar
• Nie H, Zheng Y, Li R, Guo TB, He D, Zhang JZ, et al. Phosphorylation of FOXP3 controls regulatory T cell function and is inhibited by TNF-α in rheumatoid arthritis. Nat Med. 2013;19:322–8.
   PubMed Web of Science ®Google Scholar
• Chauhan SK, Saban DR, Lee HK, Dana R. Levels of Foxp3 in regulatory T cells reflect their functional status in transplantation. J Immunol. 2009;182:148–53.
   PubMed Web of Science ®Google Scholar
• Aruna BV, Sela M, and Mozes E. Suppression of myasthenogenic responses of a T cell line by a dual altered peptide ligand by induction of CD4+CD25+ regulatory cells. Proc Natl Acad Sci USA. 2005;102:10285–90.
   PubMed Web of Science ®Google Scholar
• Levings MK, Sangregorio R, Sartirana C, Moschin AL, Battaglia M, Roncarolo MG, et al. Human CD25 + CD4+ T suppressor cell clones produce transforming growth factor beta, but not interleukin 10, and are distinct from type 1 T regulatory cells. J Exp Med. 2002;196:1335–46.
   PubMed Web of Science ®Google Scholar
• Kanamaru F, Youngnak P, Hashiguchi M, Nishioka T, Takahashi T, Azuma M, et al. Costimulation via glucocorticoid-induced TNF receptor in both conventional and CD25+ regulatory CD4+ T cells. J Immunol. 2004;172:7306–14.
   PubMed Web of Science ®Google Scholar
• Petrillo MG, Ronchetti S, Ricci E, Alunno A, Gerli R, Riccardi C, et al. GITR + regulatory T cells in the treatment of autoimmune diseases. Autoimmun Rev. 2015;14:117–26.
   PubMed Web of Science ®Google Scholar
• Stephens GL, McHugh RS, Whitters MJ, Young DA, Luxenberg D, Shevach EM, et al. Engagement of glucocorticoid-induced TNFR family-related receptor on effector T cells by its ligand mediates resistance to suppression by CD4+CD25+ T cells. J Immunol. 2004;173:5008–20.
   PubMed Web of Science ®Google Scholar
• Ronchetti S, Ricci E, Petrillo MG, Cari L, Migliorati G, Riccardi C, et al. Glucocorticoid-induced tumour necrosis factor receptor-related protein: a key marker of functional regulatory T cells. J Immunol Res. 2015;2015:171520. doi: 10.1155/2015/171520
   PubMed Web of Science ®Google Scholar
• Ogino H, Nakamura K, Ihara E, Akiho H, Takayanagi R. CD4 + CD25+ regulatory T cells suppress Th17-responses in an experimental colitis model. Dig Dis Sci. 2011;56:376–86.
   PubMed Web of Science ®Google Scholar
• Zhao J, Li R, He J, Shi J, Long L, Li Z. Mucosal administration of an altered CII263-272 peptide inhibits collagen-induced arthritis by suppression of Th1/Th17 cells and expansion of regulatory T cells. Rheumatol Int. 2008;29:9–16.
   PubMed Web of Science ®Google Scholar
• Mandik-Nayak L, Wipke BT, Shih FF, Unanue ER, Allen PM. Despite ubiquitous autoantigen expression, arthritogenic autoantibody response initiates in the local lymph node. Proc Natl Acad Sci U S A. 2002;99:14368–73.
   PubMed Web of Science ®Google Scholar
• Schubert D, Maier B, Morawietz L, Krenn V, Kamradt T. Immunization with glucose-6-phosphate isomerase induces T cell-dependent peripheral polyarthritis in genetically unaltered mice. J Immunol. 2004;172:4503–9.
   PubMed Web of Science ®Google Scholar
• Bosello S, Youinou P, Daridon C, Tolusso B, Bendaoud B, Ferraccioli G, et al. Concentrations of BAFF correlate with autoantibody levels, clinical disease activity, and response to treatment in early rheumatoid arthritis. J Rheumatol. 2008;35:1256–64.
   PubMed Web of Science ®Google Scholar
• Xu A, Liu Y, Chen W, Wang J, Xue Y, Zheng SG, et al. TGF-β-induced regulatory T cells directly suppress B cell responses through a noncytotoxic mechanism. J Immunol. 2016;196:3631–41.
   PubMed Web of Science ®Google Scholar
• Zeng B, Kwak-Kim J, Liu Y, Liao AH. Treg cells are negatively correlated with increased memory B cells in pre-eclampsia while maintaining suppressive function on autologous B-cell proliferation. Am J Reprod Immunol. 2013;70:454–63.
   PubMed Web of Science ®Google Scholar
• Teodorovic LS, Riccardi C, Torres RM, Pelanda R. Murine B cell development and antibody responses to model antigens are not impaired in the absence of the TNF receptor GITR. PLoS One. 2012;7:e31632.
   Google Scholar
• Ding CH, Li Q, Xiong ZY, Zhou AW, Jones G, Xu SY. Oral administration of type II collagen suppresses pro-inflammatory mediator production by synoviocytes in rats with adjuvant arthritis. Clin Exp Immunol. 2003;132:416–23.
   PubMed Web of Science ®Google Scholar
• Myers LK, Rosloniec EF, Seyer JM, Stuart JM, Kang AH. A synthetic peptide analogue of a determinant of type II collagen prevents the onset of collagen-induced arthritis. J Immunol. 1993;150:4652–8.
   PubMed Web of Science ®Google Scholar
• Park KS, Park MJ, Cho ML, Kwok SK, Ju JH, Kim HY, et al. Type II collagen oral tolerance; mechanism and role in collagen-induced arthritis and rheumatoid arthritis. Mod Rheumatol. 2009;19:581–9.
   PubMed Web of Science ®Google Scholar
• Min SY, Hwang SY, Park KS, Lee JS, Lee KE, Kim HY, et al. Induction of IL-10-producing CD4 + CD25+ T cells in animal model of collagen-induced arthritis by oral administration of type II collagen. Arthritis Res Ther. 2004;6:R213–19.
   PubMed Web of Science ®Google Scholar