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Rheumatoid Arthritis

Tocilizumab can efficiently prevent bone destruction in patients with recent-onset rheumatoid arthritis

Pages 966-971 | Received 08 Jul 2020, Accepted 26 Nov 2020, Published online: 18 Jan 2021

References

  • Hirabayashi Y, Munakata Y, Miyata M, Urata Y, Saito K, Okuno H, Michinoku Tocilizumab Study Group, et al. Clinical and structural remission rates increased annually and radiographic progression was continuously inhibited during a 3-year administration of tocilizumab in patients with rheumatoid arthritis: a multi-center, prospective cohort study by the Michinoku Tocilizumab Study Group. Mod Rheumatol. 2016;26(6):828–35.
  • Hirabayashi Y. Tocilizumab, an anti-interleukin-6 receptor antibody, efficiently ameliorates persistent joint inflammation in rheumatoid arthritis. Mod Rheumatol. 2021;31(1):70–79.
  • Murakami M, Hirano T. The pathological and physiological roles of IL-6 amplifier activation. Int J Biol Sci. 2012;8(9):1267–80.
  • Baillet A, Gossec L, Paternotte S, Etcheto A, Combe B, Meyer O, et al. Evaluation of serum interleukin-6 level as a surrogate marker of synovial inflammation and as a factor of structural progression in early rheumatoid arthritis: results from a French national multicenter cohort. Arthritis Care Res (Hoboken). 2015;67(7):905–12.
  • Kondo Y, Kaneko Y, Sugiura H, Matsumoto S, Nishina N, Kuwana M, et al. Pre-treatment interleukin-6 levels strongly affect bone erosion progression and repair detected by magnetic resonance imaging in rheumatoid arthritis patients. Rheumatology. 2017;56(7):1089–94.
  • Nishimoto N, Hashimoto J, Miyasaka N, Yamamoto K, Kawai S, Takeuchi T, et al. Study of active controlled monotherapy used for rheumatoid arthritis, an IL-6 inhibitor (SAMURAI): evidence of clinical and radiographic benefit from an X ray reader-blinded randomised controlled trial of tocilizumab. Ann Rheum Dis. 2007;66(9):1162–7.
  • Finzel S, Kraus S, Figueiredo CP, Regensburger A, Kocijan R, Rech J, et al. Comparison of the effects of tocilizumab monotherapy and adalimumab in combination with methotrexate on bone erosion repair in rheumatoid arthritis. Ann Rheum Dis. 2019;78(9):1186–91.
  • Watanabe R, Hirabayashi Y, Okuno H, Ishii T, Harigae H. Dramatic radiographic repair by tocilizumab in a very elderly patient with rheumatoid arthritis. Mod Rheumatol. 2014;24(6):1028–9.
  • Burmester GR, Rigby WF, van Vollenhoven RF, Kay J, Rubbert-Roth A, Blanco R, et al. Tocilizumab combination therapy or monotherapy or methotrexate monotherapy in methotrexate-naive patients with early rheumatoid arthritis: 2-year clinical and radiographic results from the randomised, placebo-controlled FUNCTION trial. Ann Rheum Dis. 2017;76(7):1279–84.
  • Bijlsma JWJ, Welsing PMJ, Woodworth TG, Middelink LM, Attila Pethö-Schramm A, Bernasconi C, et al. Early rheumatoid arthritis treated with tocilizumab, methotrexate, or their combination (U-Act-Early): a multicentre, randomise, double-blind, double-dummy, strategy trial. Lancet. 2016;388(10042):343–55.
  • Backhaus M, Kamradt T, Sandrock D, Loreck D, Fritz J, Wolf KJ, et al. Arthritis of the finger joints: a comprehensive approach comparing conventional radiography, scintigraphy, ultrasound, and contrast-enhanced magnetic resonance imaging. Arthritis Rheum. 1999;42(6):1232–45.

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