Publication Cover
Human Fertility
an international, multidisciplinary journal dedicated to furthering research and promoting good practice
Volume 26, 2023 - Issue 3
165
Views
0
CrossRef citations to date
0
Altmetric
Original Articles

Single-dose methotrexate-based protocol for the treatment of caesarean scar pregnancy and successive pregnancy outcomes

, ORCID Icon, ORCID Icon, , , , & show all
Pages 582-588 | Received 28 Dec 2020, Accepted 25 Jul 2021, Published online: 29 Aug 2021

References

  • Birch Petersen, K., Hoffmann, E., Rifbjerg Larsen, C., & Svarre Nielsen, H. (2016). Cesarean scar pregnancy: a systematic review of treatment studies. Fertility and Sterility, 105(4), 958–967. https://doi.org/10.1016/j.fertnstert.2015.12.130
  • Cheng, L. Y., Wang, C. B., Chu, L. C., Tseng, C. W., & Kung, F. T. (2014). Outcomes of primary surgical evacuation during the first trimester in different types of implantation in women with cesarean scar pregnancy. Fertility and Sterility, 102(4), 1085–1090. https://doi.org/10.1016/j.fertnstert.2014.07.003
  • Diagnosis and management of ectopic pregnancy: Green-top Guideline No. 21. (2016). BJOG, 123(13), e15–e55. https://doi.org/10.1111/1471-0528.14189
  • Dior, U. P., Palma-Dias, R., Reidy, K. L., Cheng, C., & Healey, M. (2019). Cesarean Scar pregnancies: Incidence and factors associated with conversion to surgery from medical management. Journal of Minimally Invasive Gynecology, 26(5), 919–927. https://doi.org/10.1016/j.jmig.2018.09.771
  • Giampaolino, P., De Rosa, N., Morra, I., Bertrando, A., Di Spiezio Sardo, A., Zizolfi, B., Ferrara, C., Della Corte, L., & Bifulco, G. (2018). Management of Cesarean scar pregnancy: A single-institution retrospective review. BioMed Research International, 2018, 6486407. https://doi.org/10.1155/2018/6486407
  • Glenn, T. L., Bembry, J., Findley, A. D., Yaklic, J. L., Bhagavath, B., Gagneux, P., & Lindheim, S. R. (2018). Cesarean scar ectopic pregnancy: Current management strategies. Obstetrical & Gynecological Survey, 73(5), 293–302. https://doi.org/10.1097/OGX.0000000000000561
  • Grechukhina, O., Deshmukh, U., Fan, L., Kohari, K., Abdel-Razeq, S., Bahtiyar, M. O., & Sfakianaki, A. K. (2018). Cesarean scar pregnancy, incidence, and recurrence: Five-year experience at a single tertiary care referral center. Obstetrics and Gynecology, 132(5), 1285–1295. https://doi.org/10.1097/AOG.0000000000002940
  • Jabeen, K., & Karuppaswamy, J. (2018). Non-surgical management of caesarean scar ectopic pregnancy – A five-year experience. Journal of Obstetrics and Gynaecology, 38(8), 1121–1127. https://doi.org/10.1080/01443615.2018.1451986
  • Jurkovic, D., Knez, J., Appiah, A., Farahani, L., Mavrelos, D., & Ross, J. A. (2016). Surgical treatment of Cesarean scar ectopic pregnancy: Efficacy and safety of ultrasound-guided suction curettage. Ultrasound in Obstetrics & Gynecology, 47(4), 511–517. https://doi.org/10.1002/uog.15857
  • Lai, Y. M., Lee, J. D., Lee, C. L., Chen, T. C., & Soong, Y. K. (1995). An ectopic pregnancy embedded in the myometrium of a previous cesarean section scar. Acta Obstetricia et Gynecologica Scandinavica, 74(7), 573–576. https://doi.org/10.3109/00016349509024394
  • Levin, G., Zigron, R., Dior, U. P., Gilad, R., Shushan, A., Benshushan, A., & Rottenstreich, A. (2019). Conservative management of Caesarean scar pregnancies with systemic multidose methotrexate: Predictors of treatment failure and reproductive outcomes. Reproductive Biomedicine Online, 39(5), 827–834. https://doi.org/10.1016/j.rbmo.2019.05.015
  • Maheux-Lacroix, S., Li, F., Bujold, E., Nesbitt-Hawes, E., Deans, R., & Abbott, J. (2017). Cesarean Scar pregnancies: A systematic review of treatment options. Journal of Minimally Invasive Gynecology, 24(6), 915–925. https://doi.org/10.1016/j.jmig.2017.05.019
  • Maymon, R., Svirsky, R., Smorgick, N., Mendlovic, S., Halperin, R., Gilad, K., Tovbin, J., & Tobvin, Y. (2011). Fertility performance and obstetric outcomes among women with previous cesarean scar pregnancy. Journal of Ultrasound in Medicine, 30(9), 1179–1184. https://doi.org/10.7863/jum.2011.30.9.1179
  • Peng, P., Gui, T., Liu, X., Chen, W., & Liu, Z. (2015). Comparative efficacy and safety of local and systemic methotrexate injection in cesarean scar pregnancy. Therapeutics and Clinical Risk Management, 11, 137–142. https://doi.org/10.2147/TCRM.S76050
  • Society for Maternal-Fetal Medicine (SMFM), Miller, R., Timor-Tritsch, I. E., & Gyamfi-Bannerman, C. (2020). Society for Maternal-Fetal Medicine (SMFM) Consult Series #49: Cesarean scar pregnancy. American Journal of Obstetrics and Gynecology, 222(5), B2–B14. https://doi.org/10.1016/j.ajog.2020.01.030
  • Tahaoglu, A. E., Dogan, Y., Bakir, M. S., Baglı, I., Peker, N., Cavus, Y., Togrul, C., & Tahaoglu, Z. (2019). A single centre’s experience of caesarean scar pregnancy and proposal of a management algorithm. Journal of Obstetrics and Gynaecology, 39(2), 259–264. https://doi.org/10.1080/01443615.2018.1499714
  • Timor-Tritsch, I. E., & Monteagudo, A. (2012). Unforeseen consequences of the increasing rate of cesarean deliveries: Early placenta accreta and cesarean scar pregnancy. A review. American Journal of Obstetrics and Gynecology, 207(1), 14–29. https://doi.org/10.1016/j.ajog.2012.03.007
  • Timor-Tritsch, I. E., Monteagudo, A., Santos, R., Tsymbal, T., Pineda, G., & Arslan, A. A. (2012). The diagnosis, treatment, and follow-up of cesarean scar pregnancy. American Journal of Obstetrics and Gynecology, 207(1), 44.e1–E13. https://doi.org/10.1016/j.ajog.2012.04.018
  • Wang, J. H., Qian, Z. D., Zhuang, Y. L., Du, Y. J., Zhu, L. H., & Huang, L. L. (2013). Risk factors for intraoperative hemorrhage at evacuation of a cesarean scar pregnancy following uterine artery embolization. International Journal of Gynecology & Obstetrics, 123(3), 240–243. https://doi.org/10.1016/j.ijgo.2013.06.029
  • Wang, M., Yang, Z., Li, Y., Chen, B., Wang, J., Ma, X., & Wang, Y. (2015). Conservative management of cesarean scar pregnancies: A prospective randomized controlled trial at a single center. International Journal of Clinical and Experimental Medicine, 8(10), 18972–18980.
  • Yang, Q., Piao, S., Wang, G., Wang, Y., & Liu, C. (2009). Hysteroscopic surgery of ectopic pregnancy in the cesarean section scar. Journal of Minimally Invasive Gynecology, 16(4), 432–436. https://doi.org/10.1016/j.jmig.2009.03.015
  • Yang, X. Y., Yu, H., Li, K. M., Chu, Y. X., & Zheng, A. (2010). Uterine artery embolisation combined with local methotrexate for treatment of caesarean scar pregnancy. BJOG, 117(8), 990–996. https://doi.org/10.1111/j.1471-0528.2010.02578.x

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.