Clomiphene citrate priming increases sensitivity during ovarian stimulation in poor ovarian responders undergoing in vitro fertilization treatment: a retrospective cohort study

References

• Alviggi, C., Conforti, A., Esteves, S. C., Vallone, R., Venturella, R., Staiano, S., Castaldo, E., Andersen, C. Y., & De Placido, G. (2018). Understanding ovarian hypo-response to exogenous gonadotropin in ovarian stimulation and its new proposed marker-the follicle-to-oocyte (FOI) index. Frontiers in Endocrinology, 9, 589. https://doi.org/10.3389/fendo.2018.00589
   PubMed Web of Science ®Google Scholar
• Ashrafi, M., Arabipoor, A., Yahyaei, A., Zolfaghari, Z., & Ghaffari, F. (2018). Does the “delayed start” protocol with gonadotropin-releasing hormone antagonist improve the pregnancy outcome in Bologna poor responders? A randomized clinical trial. Reproductive Biology and Endocrinology, 16(7), 124. https://doi.org/10.1186/s12958-018-0442-y
   PubMedGoogle Scholar
• Bechtejew, T. N., Nadai, M. N., Nastri, C. O., & Martins, W. P. (2017). Clomiphene citrate and letrozole to reduce follicle-stimulating hormone consumption during ovarian stimulation: Systematic review and meta-analysis. Ultrasound in Obstetrics & Gynecology, 50(3), 315–323. https://doi.org/10.1002/uog.17442
   PubMedGoogle Scholar
• Chaube, S. K., Prasad, P. V., Thakur, S. C., & Shrivastav, T. G. (2005). Estradiol protects clomiphene citrate-induced apoptosis in ovarian follicular cells and ovulated cumulus-oocyte complexes. Fertility and Sterility, 84 Suppl 2, 1163–1172. https://doi.org/10.1016/j.fertnstert.2005.03.073
   PubMed Web of Science ®Google Scholar
• Errázuriz, J., Romito, A., Drakopoulos, P., Frederix, B., Racca, A., De Munck, N., Tournaye, H., De Vos, M., & Blockeel, C. (2019). Cumulative live birth rates following stimulation with corifollitropin alfa compared with hp-hMG in a GnRH antagonist protocol in poor ovarian responders. Frontiers in Endocrinology, 10, 175. https://doi.org/10.3389/fendo.2019.00175
   PubMed Web of Science ®Google Scholar
• Ferraretti, A. P., La Marca, A., Fauser, B. C., Tarlatzis, B., Nargund, G., & Gianaroli, L. (2011). ESHRE consensus on the definition of ‘poor response’ to ovarian stimulation for in vitro fertilization: the Bologna criteria. Human Reproduction, 26(7), 1616–1624. https://doi.org/10.1093/humrep/der092
   PubMed Web of Science ®Google Scholar
• Gaba, A., Horath, S., Hager, M., Marculescu, R., & Ott, J. (2019). Basal anti Mullerian hormone levels and endometrial thickness at midcycle can predict the outcome after clomiphene citrate stimulation in anovulatory women with PCOS, a retrospective study. Archives of Gynecology and Obstetrics, 300(6), 1751–1757. https://doi.org/10.1007/s00404-019-05359-7
   PubMed Web of Science ®Google Scholar
• Genro, V. K., Grynberg, M., Scheffer, J. B., Roux, I., Frydman, R., & Fanchin, R. (2011). Serum anti-Müllerian hormone levels are negatively related to Follicular Output RaTe (FORT) in normo-cycling women undergoing controlled ovarian hyperstimulation. Human Reproduction, 26(3), 671–677. https://doi.org/10.1093/humrep/deq361
   PubMed Web of Science ®Google Scholar
• Huang, P., Tang, M., & Qin, A. (2019). Progestin-primed ovarian stimulation is a feasible method for poor ovarian responders undergoing in IVF/ICSI compared to a GnRH antagonist protocol: A retrospective study. Journal of Gynecology Obstetrics and Human Reproduction, 48(2), 99–102. https://doi.org/10.1016/j.jogoh.2018.10.008
   PubMed Web of Science ®Google Scholar
• Kamath, M. S., Maheshwari, A., Bhattacharya, S., Lor, K. Y., & Gibreel, A. (2017). Oral medications including clomiphene citrate or aromatase inhibitors with gonadotropins for controlled ovarian stimulation in women undergoing in vitro fertilisation. The Cochrane Database of Systematic Reviews, 11(11), CD008528. https://doi.org/10.1002/14651858.CD008528.pub3
   PubMedGoogle Scholar
• Klinkert, E. R., Broekmans, F. J. M., Looman, C. W. N., Habbema, J. D. F., & te Velde, E. R. (2005). Expected poor responders on the basis of an antral follicle count do not benefit from a higher starting dose of gonadotrophins in IVF treatment: A randomized controlled trial. Human Reproduction, 20(3), 611–615. https://doi.org/10.1093/humrep/deh663
   PubMed Web of Science ®Google Scholar
• Lainas, T. G., Sfontouris, I. A., Venetis, C. A., Lainas, G. T., Zorzovilis, I. Z., Tarlatzis, B. C., & Kolibianakis, E. M. (2015). Live birth rates after modified natural cycle compared with high-dose FSH stimulation using GnRH antagonists in poor responders. Human Reproduction, 30(10), 2321–2330. https://doi.org/10.1093/humrep/dev198
   PubMed Web of Science ®Google Scholar
• Lehert, P., Kolibianakis, E. M., Venetis, C. A., Schertz, J., Saunders, H., Arriagada, P., Copt, S., & Tarlatzis, B. (2014). Recombinant human follicle-stimulating hormone (r-hFSH) plus recombinant luteinizing hormone versus r-hFSH alone for ovarian stimulation during assisted reproductive technology: systematic review and meta-analysis. Reproductive Biology and Endocrinology, 12, 17. https://doi.org/10.1186/1477-7827-12-17
   PubMed Web of Science ®Google Scholar
• Lekamge, D. N., Lane, M., Gilchrist, R. B., & Tremellen, K. P. (2008). Increased gonadotrophin stimulation does not improve IVF outcomes in patients with predicted poor ovarian reserve. Journal of Assisted Reproduction and Genetics, 25(11–12), 515–521. https://doi.org/10.1007/s10815-008-9266-6
   PubMed Web of Science ®Google Scholar
• Lin, L. T., Vitale, S. G., Chen, S. N., Wen, Z. H., Tsai, H. W., Chern, C. U., & Tsui, K. H. (2018). Luteal phase ovarian stimulation may improve oocyte retrieval and oocyte quality in poor ovarian responders undergoing in vitro fertilization: Preliminary results from a single-center prospective pilot study. Advances in Therapy, 35(6), 847–856. https://doi.org/10.1007/s12325-018-0713-1
   PubMed Web of Science ®Google Scholar
• Mehdinejadiani, S., Amidi, F., Mehdizadeh, M., Barati, M., Pazhohan, A., Alyasin, A., Mehdinejadiani, K., & Sobhani, A. (2019). Effects of letrozole and clomiphene citrate on Wnt signaling pathway in endometrium of polycystic ovarian syndrome and healthy women. Biology of Reproduction, 100(3), 641–648. https://doi.org/10.1093/biolre/ioy187
   PubMed Web of Science ®Google Scholar
• Narkwichean, A., Maalouf, W., Baumgarten, M., Polanski, L., Raine-Fenning, N., Campbell, B., & Jayaprakasan, K. J. (2017). Efficacy of dehydroepiandrosterone (DHEA) to overcome the effect of ovarian ageing (DITTO): A proof of principle double blinded randomized placebo controlled trial. European Journal of Obstetrics & Gynecology and Reproductive Biology, 218, 39–48. https://doi.org/10.1016/j.ejogrb.2017.09.006
   PubMed Web of Science ®Google Scholar
• Nouri, K., Walch, K., Weghofer, A., Imhof, M., Egarter, C., & Ott, J. (2017). The impact of a standardized oral multinutrient supplementation on embryo quality in in vitro fertilization/intracytoplasmic sperm injection: A prospective randomized trial. Gynecologic and Obstetric Investigation, 82(1), 8–14. https://doi.org/10.1159/000452662
   PubMed Web of Science ®Google Scholar
• Oktem, M., Guler, I., Erdem, M., Erdem, A., Bozkurt, N., & Karabacak, O. (2015). Comparison of the effectiveness of clomiphene citrate versus letrozole in mild IVF in poor prognosis subfertile women with failed IVF cycles. International Journal of Fertility & Sterility, 9(3), 285–291. https://doi.org/10.22074/ijfs.2015.4542
   PubMedGoogle Scholar
• Pilehvari, S., ShahrokhTehraninejad, E., Hosseinrashidi, B., Keikhah, F., Haghollahi, F., & Aziminekoo, E. (2016). Comparison pregnancy outcomes between minimal stimulation protocol and conventional GnRH antagonist protocols in poor ovarian responders. Journal of Family & Reproductive Health, 10(1), 35–42. https://jfrh.tums.ac.ir/index.php/jfrh/article/view/373
   PubMedGoogle Scholar
• Robert, R., Naiha, M., & Laura, D. (2017). Ovarian stimulation in poor responders: Have we made progress? Current Pharmaceutical Biotechnology, 18(8), 614–618. https://doi.org/10.2174/1389201018666171002132853
   PubMed Web of Science ®Google Scholar
• Safdarian, L., Aghahosseini, M., Alyasin, A., Samaei Nouroozi, A., Rashidi, S., Shabani Nashtaei, M., Najafian, A., & Lak, P. (2019). Growth hormone (GH) improvement of ovarian responses and pregnancy outcome in poor ovarian responders: A randomized study. Asian Pacific Journal of Cancer Prevention, 20(7), 2033–2037. https://doi.org/10.31557/APJCP.2019.20.7.2033
   PubMedGoogle Scholar
• Sfakianoudis, K., Pantos, K., Grigoriadis, S., Rapani, A., Maziotis, E., Tsioulou, P., Giannelou, P., Kontogeorgi, A., Pantou, A., Vlahos, N., Koutsilieris, M., & Simopoulou, M. (2020). What is the true place of a double stimulation and double oocyte retrieval in the same cycle for patients diagnosed with poor ovarian reserve? A systematic review including a meta-analytical approach. Journal of Assisted Reproduction and Genetics, 37(1), 181–204. https://doi.org/10.1007/s10815-019-01638-z
   PubMed Web of Science ®Google Scholar
• Sunkara, S. K., Rittenberg, V., Raine-Fenning, N., Bhattacharya, S., Zamora, J., & Coomarasamy, A. (2011). Association between the number of eggs and live birth in IVF treatment: An analysis of 400 135 treatment cycles. Human Reproduction, 26(7), 1768–1774. https://doi.org/10.1093/humrep/der106
   PubMed Web of Science ®Google Scholar
• van Tilborg, T. C., Torrance, H. L., Oudshoorn, S. C., Eijkemans, M., Koks, C., Verhoeve, H. R., Nap, A. W., Scheffer, G. J., Manger, A. P., Schoot, B. C., Sluijmer, A. V., Verhoeff, A., Groen, H., Laven, J., Mol, B., & Broekmans, F. (2017). Individualized versus standard FSH dosing in women starting IVF/ICSI: an RCT. Part 1: The predicted poor responder. Human Reproduction, 32(12), 2496–2505. https://doi.org/10.1093/humrep/dex318
   PubMed Web of Science ®Google Scholar
• Xu, Y., Nisenblat, V., Lu, C., Li, R., Qiao, J., Zhen, X., & Wang, S. (2018). Pretreatment with coenzyme Q10 improves ovarian response and embryo quality in low-prognosis young women with decreased ovarian reserve: a randomized controlled trial. Reproductive Biology and Endocrinology, 16(1), 29. https://doi.org/10.1186/s12958-018-0343-0
   PubMedGoogle Scholar