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Human Fertility
an international, multidisciplinary journal dedicated to furthering research and promoting good practice
Volume 26, 2023 - Issue 2
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Articles

Is the use of IVF add-on treatments driven by patients or clinics? Findings from a UK patient survey

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Pages 365-372 | Received 06 Sep 2022, Accepted 15 Mar 2023, Published online: 16 Apr 2023

References

  • Armstrong, S., Atkinson, M., MacKenzie, J., Pacey, A., & Farquhar, C. (2019). Add-ons in the laboratory: hopeful, but not always helpful. Fertility and Sterility, 112(6), 994–999. https://doi.org/10.1016/j.fertnstert.2019.10.031
  • Ben Rafael, Z. (2020). Repeated implantation failure (RIF): an iatrogenic meaningless definition that generates unnecessary and costly use of add-on procedures. Human Reproduction (Oxford, England), 35(7), 1479–1483. https://doi.org/10.1093/humrep/deaa134
  • Brody, H. (1997). Medical futility: a useful concept?. In M. B. Zucker, & H. D. Zucker (Eds.), Medical Futility: And the Evaluation of Life-Sustaining Interventions. (pp. 1–14). Cambridge University Press. https://doi.org/10.1017/CBO9780511530227
  • Chambers, G. M., Dyer, S., Zegers-Hochschild, F., de Mouzon, J., Ishihara, O., Banker, M., Mansour, R., Kupka, M. S., & Adamson, G. D. (2021). International Committee for Monitoring Assisted Reproductive Technologies world report: assisted reproductive technology, 2014†. Human Reproduction (Oxford, England), 36(11), 2921–2934. https://doi.org/10.1093/humrep/deab198
  • CMA. (2021). Guidance for fertility clinics on consumer law: Helping fertility clinics comply with their consumer law obligations. Competition & Markets Authority.
  • Cornelisse, S., Zagers, M., Kostova, E., Fleischer, K., Wely, M., & Mastenbroek, S. (2020). Preimplantation genetic testing for aneuploidies (abnormal number of chromosomes) in in vitro fertilisation. The Cochrane Database of Systematic Reviews, 9(9), CD005291. https://doi.org/10.1002/14651858.CD005291.pub3
  • Harper, J., Jackson, E., Sermon, K., Aitken, R. J., Harbottle, S., Mocanu, E., Hardarson, T., Mathur, R., Viville, S., Vail, A., & Lundin, K. (2017). Adjuncts in the IVF laboratory: where is the evidence for 'add-on’ interventions? Human Reproduction (Oxford, England), 32(3), 485–491. https://doi.org/10.1093/humrep/dex004
  • Heneghan, C., Spencer, E. A., Bobrovitz, N., Collins, D. R., Nunan, D., Plüddemann, A., Gbinigie, O. A., Onakpoya, I., O'Sullivan, J., Rollinson, A., Tompson, A., Goldacre, B., & Mahtani, K. R. (2016). Lack of evidence for interventions offered in UK fertility centres. BMJ (Clinical Research ed.), 355, i6295. https://doi.org/10.1136/bmj.i6295
  • HFEA. (2018). Human Fertilisation and Embryology Authority. Treatment add-ons. https://www.hfea.gov.uk/treatments/explore-all-treatments/treatment-add-ons/
  • HFEA. (2021). Fertility treatment 2019: trends and figures. https://www.hfea.gov.uk/about-us/publications/research-and-data/fertility-treatment-2019-trends-and-figures/).HFEA
  • HFEA. (2022). Treatment add-ons with limited evidence. https://www.hfea.gov.uk/treatments/treatment-add-ons/
  • Human Fertilisation and Embryology Authority. (2018). Pilot national fertility patient survey. https://www.hfea.gov.uk/media/2702/pilot-national-fertility-patient-survey-2018.pdf
  • Iacoponi, O., van de Wiel, L., Wilkinson, J., & Harper, J. C. (2022). Passion, pressure and pragmatism: how fertility clinic medical directors view IVF add-ons. Reproductive Biomedicine Online, 45(1), 169–179. https://doi.org/10.1016/j.rbmo.2022.02.021
  • Kamath, M. S., Mascarenhas, M., Franik, S., Liu, E., & Sunkara, S. K. (2019). Clinical adjuncts in in vitro fertilization: a growing list. Fertility and Sterility, 112(6), 978–986. https://doi.org/10.1016/j.fertnstert.2019.09.019
  • Lensen, S., Chen, S., Goodman, L., Rombauts, L., Farquhar, C., & Hammarberg, K. (2021). IVF add-ons in Australia and New Zealand: A systematic assessment of IVF clinic websites. The Australian & New Zealand Journal of Obstetrics & Gynaecology, 61(3), 430–438. https://doi.org/10.1111/ajo.13321
  • Lensen, S., Hammarberg, K., Polyakov, A., Wilkinson, J., Whyte, S., Peate, M., & Hickey, M. (2021). How common is add-on use and how do patients decide whether to use them? A national survey of IVF patients. Human Reproduction (Oxford, England), 36(7), 1854–1861. https://doi.org/10.1093/humrep/deab098
  • Lensen, S., Shreeve, N., Barnhart, K. T., Gibreel, A., Ng, E. H. Y., & Moffett, A. (2019). In vitro fertilization add-ons for the endometrium: it doesn’t add-up. Fertility and Sterility, 112(6), 987–993. https://doi.org/10.1016/j.fertnstert.2019.10.011
  • NHS. (2017). Infertility. https://www.nhs.uk/conditions/infertility/
  • Perrotta, M., & Geampana, A. (2020). The trouble with IVF and randomised control trials: Professional legitimation narratives on time-lapse imaging and evidence-informed care. Social Science & Medicine (1982), 258, 113115. https://doi.org/10.1016/j.socscimed.2020.113115
  • Perrotta, M., & Hamper, J. (2021). The crafting of hope: Contextualising add-ons in the treatment trajectories of IVF patients. Social Science & Medicine (1982), 287, 114317. https://doi.org/10.1016/j.socscimed.2021.114317
  • RStudio Team. (2020). RStudio: Integrated Development for R [computer software].
  • Sarwari, M., Beilby, K., Hammarberg, K., Hickey, M., & Lensen, S. (2021). Endometrial scratching in Australia, New Zealand and the United Kingdom (UK): a follow-up survey. Human Fertility, 14, 1–6. https://doi.org/10.1080/14647273.2021.1995902
  • Spencer, E. A., Mahtani, K. R., Goldacre, B., & Heneghan, C. (2016). Claims for fertility interventions: a systematic assessment of statements on UK fertility centre websites. BMJ Open, 6(11), e013940. https://doi.org/10.1136/bmjopen-2016-013940
  • Stein, J., & Harper, J. C. (2021). Analysis of fertility clinic marketing of complementary therapy add-ons. Reproductive Biomedicine & Society Online, 13, 24–36. https://doi.org/10.1016/j.rbms.2021.04.001
  • Wilkinson, J., Malpas, P., Hammarberg, K., Mahoney Tsigdinos, P., Lensen, S., Jackson, E., Harper, J., & Mol, B. W. (2019). Do à la carte menus serve infertility patients? The ethics and regulation of in vitro fertility add-ons. Fertility and Sterility, 112(6), 973–977. https://doi.org/10.1016/j.fertnstert.2019.09.028