Regenerative effect of neural-induced human mesenchymal stromal cells in rat models of Parkinson's disease

References

• Piccini P, Brooks DJ, Bjurklund A, et al. Dopamine release from nigral transplants visualized in vivo in a Parkinson's patient. Nature Neuroscience 1999; 2: 1137–40
   PubMed Web of Science ®Google Scholar
• Olanow CW, Goetz CG, Kordower JH, et al. A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease. Annals of Neurology 2003; 54: 403–14
   PubMed Web of Science ®Google Scholar
• Freed CR, Greene PE, Breeze RE, et al. Transplantation of embryonic dopamine neurons for severe Parkinson's disease. N Engl J Med 2001; 344: 710–9
   PubMed Web of Science ®Google Scholar
• Pittenger MF, Mackay AM, Beck SC, et al. Multilineage potential of adult human mesenchymal stem cells. Science 1999; 284: 143–7
   PubMed Web of Science ®Google Scholar
• Jiang Y, Jahagirdar BN, Reinhardt RL, et al. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 2002; 418: 41–9
   PubMed Web of Science ®Google Scholar
• Sanchez-Ramos J, Song S, Cardozo-Pelaez F, et al. Adult bone marrow stromal cells differentiate into neural cells in vitro. Experimental Neurology 2000; 164: 247–56
   PubMed Web of Science ®Google Scholar
• Woodbury D, Schwarz EJ, Prockop DJ, et al. Adult rat and human bone marrow stromal cells differentiate into neurons. J Neurosci Res 2000; 61: 364–70
   PubMed Web of Science ®Google Scholar
• Blondheim NR, Levy YS, Ben-Zur T, et al. Human mesenchymal stem cells express neural genes, suggesting a neural predisposition. Stem Cells and Development 2006; 15: 141–64
   PubMed Web of Science ®Google Scholar
• Hellmann MA, Panet H, Barhum Y, et al. Increased survival and migration of engrafted mesenchymal bone marrow stem cells in 6-hydroxydopamine-lesioned rodents. Neuroscience Letters 2006; 395: 124–8
   PubMed Web of Science ®Google Scholar
• Sykova E, Jendelova P. Migration, fate and in vivo imaging of adult stem cells in the CNS. Cell Death Differ 2007; 14: 1336–42
   PubMed Web of Science ®Google Scholar
• Levy YS, Merims D, Panet H, et al. Induction of neuron-specific enolase promoter and neuronal markers in differentiated mouse bone marrow stromal cells. Journal of Molecular Neuroscience 2003; 21: 121–32
   PubMed Web of Science ®Google Scholar
• Kan I, Ben-Zur T, Barhum Y, et al. Dopaminergic differentiation of human mesenchymal stem cells – Utilization of bioassay for tyrosine hydroxylase expression. Neuroscience Letters 2007; 419: 28–33
   PubMed Web of Science ®Google Scholar
• Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Analytical Biochemistry 1987; 162: 156–9
   PubMed Web of Science ®Google Scholar
• Sambrock J, Fritsch EF., Maniatis T. Molecular cloning2nd edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York 1989
   Google Scholar
• Studer L, Tabar V, MacKay RD. Transplantation of expanded mesencephalic precursors leads to recovery in parkinsonian rats. Nature Neuroscience 1998; 1: 290–5
   PubMed Web of Science ®Google Scholar
• Paxinos G, Watson C, Pennisi M, et al. Bregma, lambda and the interaural midpoint in stereotaxic surgery with rats of different sex, strain and weight. Journal of Neuroscience Methods 1985; 13: 139–43
   PubMed Web of Science ®Google Scholar
• Dominici M, Blanc KL, Mueller I, et al. Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy 2006; 8: 315–7
   PubMed Web of Science ®Google Scholar
• Saucedo-Cardenas O, Quintana-Hau JD, Le WD, et al. Nurr1 is essential for the induction of the dopaminergic phenotype and the survival of ventral mesencephalic late dopaminergic precursor neurons PNAS 1998; 95: 4013–8
   Google Scholar
• Smidt MP, Smits SM, Bouwmeester H, et al. Early developmental failure of substantia nigra dopamine neurons in mice lacking the homeodomain gene Pitx3 Development 2004; 131: 1145–55
   Google Scholar
• Schwarz EJ, Alexander GM, Prockop DJ, et al. Multipotential marrow stromal cells transduced to produce l-dopa: engraftment in a rat model of Parkinson disease. Human Gene Therapy 1999; 10: 2539–49
   PubMed Web of Science ®Google Scholar
• Li Y, Chen J, Wang L, et al. Intracerebral transplantation of bone marrow stromal cells in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease. Neuroscience Letters 2001; 316: 67–70
   PubMed Web of Science ®Google Scholar
• Park KW, Eglitis MA, Mouradian MM. Protection of nigral neurons by GDNF-engineered marrow cell transplantation. Neuroscience Research 2001; 40: 315–23
   PubMed Web of Science ®Google Scholar
• Dezawa M, Kanno H, Hoshinoo M, et al. Specific induction of neuronal cells from bone marrow stromal cells and application for autologous transplantation. Journal of Clinical Investigation 2004; 113: 1701–10
   PubMed Web of Science ®Google Scholar
• Joannides A, Gaughwin P, Scott M, et al. Postnatal astrocytes promote neural induction from adult human bone marrow-derived stem cells. Journal of Hematotherapy & Stem Cell Research 2003; 12: 681–8
   PubMedGoogle Scholar
• Hermann A, Gastl R, Liebau S, et al. Efficient generation of neural stem cell-like cells from adult human bone marrow stromal cells. J Cell Sci 2004; 117: 4411–22
   PubMed Web of Science ®Google Scholar
• Kuhn HG, Winkler J, Kempermann G, et al. Epidermal growth factor and fibroblast growth factor-2 have different effects on neural progenitors in the adult rat brain. J Neurosci 1997; 17: 5820–9
   PubMed Web of Science ®Google Scholar
• Mena MA, Casarejos MJ, Bonin A, et al. Effects of dibutyryl cyclic amp and retinoic acid on the differentiation of dopamine neurons: prevention of cell death by dibutyryl cyclic AMP. Journal of Neurochemistry 1995; 65: 2612–20
   PubMedGoogle Scholar
• Branton RL, Love RM, Clarke DJ. cAMP included during cell suspension preparation improves survival of dopaminergic neurons in vitro. Neuroreport 1998; 9: 3223–7
   Google Scholar
• Pei Y, He X, Xie Z. Dopaminergic neuron differentiation of ventral mesencephalic progenitors regulated by developmental signals in vitro. Neuroreport 2003; 14: 1567–70
   Google Scholar
• Deng W, Obrocka M, Fischer I, et al. In Vitro Differentiation of human marrow stromal cells into early progenitors of neural cells by conditions that increase intracellular cyclic AMP. Biochemical and Biophysical Research Communications 2001; 282: 148–52
   PubMed Web of Science ®Google Scholar
• Kabos P, Ehtesham M, Kabosova A, et al. Generation of neural progenitor cells from whole adult bone marrow. Experimental Neurology 2002; 178: 288–93
   PubMed Web of Science ®Google Scholar
• Ratan RR, Murphy TH, Baraban JM. Oxidative stress induces apoptosis in embryonic cortical neurons. Journal of Neurochemistry 1994; 62: 376–9
   PubMed Web of Science ®Google Scholar
• Maden M. Retinoid signalling in the development of the central nervous system. Nature Reviews Neuroscience 2002; 3: 843–53
   PubMed Web of Science ®Google Scholar
• Kalir HH, Mytilineou C. Ascorbic acid in mesencephalic cultures: effects on dopaminergic neuron development. Journal of Neurochemistry 1991; 57: 458–64
   PubMed Web of Science ®Google Scholar
• Lee SH, Lumelsky N, Studer L, et al. Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells. Nat Biotech 2000; 18: 675–9
   PubMed Web of Science ®Google Scholar
• Jori FP, Napolitano MA, Melone MAB, et al. Molecular pathways involved in neural in vitro differentiation of marrow stromal stem cells. Journal of Cellular Biochemistry 2005; 94: 645–55
   Google Scholar
• Deng W, Obrocka M, Fischer I, et al. In-vitro differentiation of human marrow stromal cells into early progenitors of neural cells by conditions that increase intracellular cyclic AMP. Biochem Biophys Res Commun 2001; 282: 148–152
   PubMed Web of Science ®Google Scholar
• Ross SE, Greenberg ME, Stiles CD. Basic helix-loop-helix factors in cortical development. Neuron 2003; 39: 13–25
   PubMed Web of Science ®Google Scholar
• Cho J, Kwon IS, Kim S, et al. Overexpression of BETA2/NeuroD induces neurite outgrowth in F11 neuroblastoma cells. J Neurochem 2001; 77: 103–109
   PubMedGoogle Scholar
• Shen M, Kawamoto T, Teramoto M, et al. Induction of basic helix-loop-helix protein DEC1 (BHLHB2)/Stra13/Sharp2 in response to the cyclic adenosine monophosphate pathway. Eur J Cell Biol 2001; 80: 329–334
   PubMedGoogle Scholar
• Garcia AD, Doan NB, Imura T, et al. GFAP-expressing progenitors are the principal source of constitutive neurogenesis in adult mouse forebrain. Nat Neurosci 2004; 7: 1233–41
   PubMed Web of Science ®Google Scholar
• Bonaguidi MA, McGuire T, Hu M, et al. LIF and BMP signaling generate separate and discrete types of GFAP-expressing cells. Development. 2005; 132: 5503–14
   PubMed Web of Science ®Google Scholar
• Lu D, Li Y, Wang L, et al. Intraarterial administration of marrow stromal cells in a rat model of traumatic brain injury. Journal of Neurotrauma 2001; 18: 813–9
   PubMed Web of Science ®Google Scholar
• Lu D, Mahmood A, Wang L, et al. Adult bone marrow stromal cells administered intravenously to rats after traumatic brain injury migrate into brain and improve neurological outcome. Neuroreport 2001; 12: 559–63
   PubMed Web of Science ®Google Scholar
• Chen J, Li Y, Wang L, et al. Therapeutic benefit of intravenous administration of bone marrow stromal cells after cerebral ischemia in rats. Stroke 2001; 32: 1005–11
   PubMed Web of Science ®Google Scholar
• Chen Y, Teng F, Tang B. Coaxing bone marrow stromal mesenchymal stem cells towards neuronal differentiation: progress and uncertainties. Cellular and Molecular Life Sciences (CMLS) 2006; 63: 1649–57
   PubMed Web of Science ®Google Scholar
• Pisati F, Bossolasco P, Meregalli M, et al. Induction of neurotrophin expression via human adult mesenchymal stem cells: implication for cell therapy in neurodegenerative diseases. Cell Transplantation 2007; 16: 41–55
   PubMed Web of Science ®Google Scholar
• Le Blanc K, Ringden O. Mesenchymal stem cells: properties and role in clinical bone marrow transplantation. Current Opinion in Immunology 2006; 18: 586–91
   PubMed Web of Science ®Google Scholar
• Deng YB, Liu XG, Liu ZG, et al. Implantation of BM mesenchymal stem cells into injured spinal cord elicits de novo neurogenesis and functional recovery: evidence from a study in rhesus monkeys. Cytotherapy 2006; 8: 210–4
   PubMed Web of Science ®Google Scholar