6,924
Views
55
CrossRef citations to date
0
Altmetric
Editorial

How can we overcome neuropsychological adverse effects of antiepileptic drugs?

&
Pages 551-554 | Received 02 Mar 2017, Accepted 16 Mar 2017, Published online: 27 Mar 2017

References

  • Perucca P, Mula M. Antiepileptic drug effects on mood and behavior: molecular targets. Epilepsy Behav. 2013;26(3):440–449. ​ ​
  • Eddy CM, Rickards HE, Cavanna AE. The cognitive impact of antiepileptic drugs. Ther Adv Neurol Disord. 2011;4(6):385–407.
  • Helmstaedter C, Elger CE, Witt J-A. The effect of quantitative and qualitative antiepileptic drug changes on cognitive recovery after epilepsy surgery. Seizure. 2016;36:63–69.
  • Witt J-A, Elger CE, Helmstaedter C. Adverse cognitive effects of antiepileptic pharmacotherapy: each additional drug matters. Eur Neuropsychopharmacol. 2015;25(11):1954–1959.
  • Trimble MR, Thompson PJ. Anticonvulsant drugs, cognitive function, and behavior. Epilepsia. 1983;24(Suppl 1):S55–63.
  • Witt J-A, Elger CE, Helmstaedter C. Impaired verbal fluency under topiramate–evidence for synergistic negative effects of epilepsy, topiramate, and polytherapy. Eur J Neurol. 2013;20(1):130–137.
  • Meador KJ. Newer anticonvulsants: dosing strategies and cognition in treating patients with mood disorders and epilepsy. J Clin Psychiatry. 2003;64(Suppl 8):30–34.
  • Witt J-A, Helmstaedter C. Monitoring the cognitive effects of antiepileptic pharmacotherapy–approaching the individual patient. Epilepsy Behav. 2013;26(3):450–456.
  • Meador KJ, Loring DW. Developmental effects of antiepileptic drugs and the need for improved regulations. Neurology. 2016;86(3):297–306.
  • Witt J-A, Elger CE, Helmstaedter C. Which drug-induced side effects would be tolerated in the prospect of seizure control? Epilepsy Behav. 2013;29(1):141–143.
  • Bootsma HP, Ricker L, Hekster YA, et al. The impact of side effects on long-term retention in three new antiepileptic drugs. Seizure. 2009 Jun;18(5):327–331.
  • Gilliam FG, Fessler AJ, Baker G, et al. Systematic screening allows reduction of adverse antiepileptic drug effects: a randomized trial. Neurology. 2004 Jan 13;62(1):23–27.
  • Dash D, Aggarwal V, Joshi R, et al. Effect of reduction of antiepileptic drugs in patients with drug-refractory epilepsy. Seizure. 2015;27:25–29.
  • Javed A, Cohen B, Detyniecki K, et al. Rates and predictors of patient-reported cognitive side effects of antiepileptic drugs: an extended follow-up. Seizure. 2015;29:34–40.
  • Widman G, Witt JA, Elger CE, et al. Does fast titration of topiramate reveal the early detection of patients who will experience negative cognitive side effects? Eur J Neurol. 2015;22(S1):338.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.