Pharmaceutical strategies for smoking cessation during pregnancy

References

• WHO report on the global tobacco epidemic . 2017: monitoring tobacco use and prevention policies. Geneva: World Health Organization; 2017. Licence: CC BY-NC-SA 3.0 IGO.
   Google Scholar
• Xu X , Bishop EE , Kennedy SM , et al. Annual healthcare spending attributable to cigarette smoking: an update. Am J Prev Med. 2015 Mar;48(3):326–333.
   PubMed Web of Science ®Google Scholar
• WHO . Recommendations for the prevention and management of tobacco use and second-hand smoke exposure in pregnancy. Geneva: World Health Organization; 2013. Available from: https://www.ncbi.nlm.nih.gov/books/NBK190304/.
   Google Scholar
• Banderali G , Martelli A , Landi M , et al. Short and long term health effects of parental tobacco smoking during pregnancy and lactation: a descriptive review. J Transl Med. 2015 Oct;15(13):327.
   Google Scholar
• Ekblad M , Gissler M , Lehtonen L , et al. Prenatal smoking exposure and the risk of psychiatric morbidity into young adulthood. Arch Gen Psychiatry. 2010 Aug;67(8):841–849.
   PubMed Web of Science ®Google Scholar
• Metzger MJ , Halperin AC , Manhart LE , et al. Association of maternal smoking during pregnancy with infant hospitalization and mortality due to infectious diseases. Pediatr Infect Dis J. 2013 Jan;32(1):e1–e7.
   PubMed Web of Science ®Google Scholar
• Neuman Å , Hohmann C , Orsini N , et al. Maternal smoking in pregnancy and asthma in preschool children: a pooled analysis of eight birth cohorts. Am J Respir Crit Care Med. 2012 Nov 15;186(10):1037–1043.
   PubMed Web of Science ®Google Scholar
• Leybovitz-Haleluya N , Wainstock T , Landau D , et al. Maternal smoking during pregnancy and the risk of pediatric cardiovascular diseases of the offspring: a population-based cohort study with up to 18-years of follow up. Reprod Toxicol. 2018 Mar 28;78:69–74.
   PubMed Web of Science ®Google Scholar
• Kandel DB , Griesler PC , Hu MC. Intergenerational Patterns of Smoking and Nicotine Dependence Among US Adolescents. Am J Public Health. 2015 Nov;105(11):e63–e72.
   PubMed Web of Science ®Google Scholar
• McAndrew F , Thompson J , Fellows L , et al. Infant Feeding Survey: Health and Social Care Information Centre, 2012.
   Google Scholar
• Bloch M , Althabe F , Onyamboko M , et al. Tobacco use and secondhand smoke exposure during pregnancy: an investigative survey of women in 9 developing nations. Am J Public Health. 2008 Oct;98(10):1833–1840.
   PubMed Web of Science ®Google Scholar
• National Health Service Digital . Statistics on Women’s Smoking Status at Time of Delivery, England - Quarter 1, 2017-18. September 2017. [cited 2018 May 4]. Available from: https://digital.nhs.uk/catalogue/PUB30070
   Google Scholar
• Drake P , Driscoll AK , Mathews TJ. Cigarette smoking during pregnancy: united States, 2016. NCHS Data Brief, no 305. Hyattsville, MD: National Center for Health Statistics; 2018.
   Google Scholar
• Vaz LR , Coleman T , Cooper S , et al. The Nicotine Metabolite Ratio in Pregnancy Measured by trans-3ʹ-Hydroxycotinine to Cotinine Ratio: characteristics and Relationship with Smoking Cessation. Nicotine Tob Res. 2015 Nov;17(11):1318–1323.
   PubMed Web of Science ®Google Scholar
• Hannöver W , Thyrian JR , Röske K , et al. Smoking cessation and relapse prevention for postpartum women: results from a randomized controlled trial at 6, 12, 18 and 24 months. Addict Behav. 2009;34(1):1–8.
   PubMed Web of Science ®Google Scholar
• Cooper S , Orton S , Leonardi-Bee J , et al. Smoking and quit attempts during pregnancy and postpartum: a longitudinal UK cohort. BMJ Open. 2017 Nov 15;7(11):e018746.
   PubMed Web of Science ®Google Scholar
• Verbiest M , Brakema E , van der Kleij R , et al. National guidelines for smoking cessation in primary care: a literature review and evidence analysis. NPJ Prim Care Respir Med. 2017 Jan 20;27(1):2.
   PubMedGoogle Scholar
• Fiore M , Jaen C , Baker T , et al. Tobacco use and dependence guideline panel. Treating tobacco use and dependence: 2008 update. Rockville, MD: US Department of Health and Human Services; 2008.
   Google Scholar
• U.S. Preventive Services Task Force . Behavioral and Pharmacotherapy Interventions for Tobacco Smoking Cessation in Adults, Including Pregnant Women: U.S. Preventive Services Task Force Recommendation Statement. Ann Intern Med. 2015 Oct 20;163:(8)622–634.
   PubMed Web of Science ®Google Scholar
• Coleman T , Chamberlain C , Davey MA , et al. Pharmacological interventions for promoting smoking cessation during pregnancy. Cochrane Database Syst Rev. 2015 Dec 22;(12):CD010078. doi: 10.1002/14651858.CD010078.pub2.
   PubMed Web of Science ®Google Scholar
• Jaddoe VW , Troe EJ , Hofman A , et al. Active and passive maternal smoking during pregnancy and the risks of low birthweight and preterm birth: the generation R study. Paediatr Perinat Epidemiol. 2008 Mar;22(2):162–171.
   PubMed Web of Science ®Google Scholar
• Taghavi T , Arger CA , Heil SH , et al. Longitudinal influence of pregnancy on nicotine metabolic pathways. J Pharmacol Exp Ther. 2018 Feb;364(2):238–245.
   PubMed Web of Science ®Google Scholar
• Dempsey D , Jacob P 3rd , Benowitz NL. Accelerated metabolism of nicotine and cotinine in pregnant smokers. J Pharmacol Exp Ther. 2002 May;301(2):594–598.
   PubMed Web of Science ®Google Scholar
• Fokina VM , Xu M , Rytting E , et al. Pharmacokinetics of bupropion and its pharmacologically active metabolites in pregnancy. Drug Metab Dispos. 2016 Nov;44(11):1832–1838.
   PubMed Web of Science ®Google Scholar
• Dhalwani NN , Szatkowski L , Coleman T , et al. Prescribing of nicotine replacement therapy in and around pregnancy: a population-based study using primary care data. Br J Gen Pract. 2014 Sep;64(626):e554–e560.
   PubMed Web of Science ®Google Scholar
• Rigotti NA , Park ER , Chang Y , et al. Smoking cessation medication use among pregnant and postpartum smokers. Obstet Gynecol. 2008;111(2 Pt 1):348–355.
   PubMed Web of Science ®Google Scholar
• Johnson M , Anderson P , Lockhart I . General practitioner prescribing of single and combination nicotine replacement therapy in the UK: a retrospective database study. BMC Fam Pract. 2014 Mar;20(15):47.
   Google Scholar
• Dhalwani NN , Szatkowski L , Coleman T . Nicotine replacement therapy in pregnancy and major congenital anomalies in offspring. Pediatrics. 2015 May;135(5):859–867.
   PubMed Web of Science ®Google Scholar
• Dhalwani NN , Szatkowski L , Coleman T , et al. Stillbirth among women prescribed nicotine replacement therapy in pregnancy: analysis of a large UK pregnancy cohort. Nicotine Tob Res. 2018 Jan 31. doi: 10.1093/ntr/nty019. [Epub ahead of print].
   PubMed Web of Science ®Google Scholar
• Lassen TH , Madsen M , Skovgaard LT , et al. Maternal use of nicotine replacement therapy during pregnancy and offspring birthweight: a study within the Danish National Birth Cohort. Paediatr Perinat Epidemiol. 2010;24:272–281.
   PubMed Web of Science ®Google Scholar
• Strandberg-Larsen K , Tinggaard M , Nybo Andersen AM , et al. Use of nicotine replacement therapy during pregnancy and stillbirth: a cohort study. Bjog. 2008;115:1405–1410.
   PubMed Web of Science ®Google Scholar
• Bérard A , Zhao JP , Sheehy O . Success of smoking cessation interventions during pregnancy. Am J Obstet Gynecol. 2016 Nov;215(5):611.e1–611.e8.
   Web of Science ®Google Scholar
• Wisborg K , Henriksen TB , Jespersen LB , et al. Nicotine patches for pregnant smokers: a randomized controlled study. Obstet Gynecol. 2000 Dec;96(6):967–971.
   PubMed Web of Science ®Google Scholar
• Kapur B , Hackman R , Selby P , et al. Randomized, double-blind, placebo-controlled trial of nicotine replacement therapy in pregnancy. Curr Ther Res Clin Exp. 2001;62(4):274–278.
   Web of Science ®Google Scholar
• Hartmann-Boyce J , Chepkin SC , Ye W , et al. Nicotine replacement therapy versus control for smoking cessation. Cochrane Database Syst Rev. 2018 May 31;(5):CD000146. doi: 10.1002/14651858.CD000146.pub5.
   PubMed Web of Science ®Google Scholar
• Oncken C , Dornelas E , Greene J , et al. Nicotine gum for pregnant smokers: a randomized controlled trial. Obstet Gynecol. 2008 Oct;112(4):859–867.
   PubMed Web of Science ®Google Scholar
• Berlin I , Grangé G , Jacob N , et al. Nicotine patches in pregnant smokers: randomized, placebo controlled, multicenter trial of efficacy. BMJ. 2014 Mar;11(348):g1622.
   Google Scholar
• Coleman T , Cooper S , Thornton JG , et al. A randomized trial of nicotine-replacement therapy patches in pregnancy. N Engl J Med. 2012 Mar 1;366(9):808–818.
   PubMed Web of Science ®Google Scholar
• Cooper S , Taggar J , Lewis S , et al. Effect of nicotine patches in pregnancy on infant and maternal outcomes at 2 years: follow-up from the randomised, double-blind, placebo-controlled SNAP trial. Lancet Respir Med. 2014 Sep;2(9):728–737.
   PubMed Web of Science ®Google Scholar
• Ekblad M , Korkeila J , Lehtonen L . Smoking during pregnancy affects foetal brain development. Acta Paediatr. 2015 Jan;104(1):12–18.
   PubMed Web of Science ®Google Scholar
• Slemmer JE , Martin BR , Damaj MI . Bupropion is a nicotinic antagonist. J Pharmacol Exp Ther. 2000 Oct;295(1):321–327.
   PubMed Web of Science ®Google Scholar
• Warner C , Shoaib M . How does bupropion work as a smoking cessation aid?. Addict Biol. 2005;10(1):23–35.
   PubMed Web of Science ®Google Scholar
• Pandhare A , Pappu AS , Wilms H , et al. The antidepressant bupropion is a negative allosteric modulator of serotonin type 3A receptors. Neuropharmacology. 2017 Feb;113(Pt A):89–99.
   PubMedGoogle Scholar
• Bupropion (amfebutamone): caution during pregnancy. Prescrire Int. 2005 Dec;14(80):225.
   Google Scholar
• Cole JA , Modell JG , Haight BR , et al. Bupropion in pregnancy and the prevalence of congenital malformations. Pharmacoepidemiol Drug Saf. 2007 May;16(5):474–484.
   PubMed Web of Science ®Google Scholar
• Chun-Fai-Chan B , Koren G , Fayez I , et al. Preginancy outcome of women exposed to bupropion during pregnancy: a prospective comparative study. Am J Obstet Gynecol. 2005 Mar;192(3):932–936.
   PubMed Web of Science ®Google Scholar
• Alwan S , Reefhuis J , Botto LD , et al. Maternal use of bupropion and risk for congenital heart defects. Am J Obstet Gynecol. 2010 Jul;203(1):52.e1-6.
   PubMed Web of Science ®Google Scholar
• Louik C , Kerr S , Mitchell AA . First-trimester exposure to bupropion and risk of cardiac malformations. Pharmacoepidemiol Drug Saf. 2014 Oct;23(10):1066–1075.
   PubMed Web of Science ®Google Scholar
• Grote NK , Bridge JA , Gavin AR , et al. A meta-analysis of depression during pregnancy and the risk of preterm birth, low birth weight, and intrauterine growth restriction. Arch Gen Psychiatry. 2010 Oct;67(10):1012–1024.
   PubMed Web of Science ®Google Scholar
• Chan B , Einarson A , Koren G . Effectiveness of bupropion for smoking cessation during pregnancy. J Addict Dis. 2005;24(2):19–23.
   PubMed Web of Science ®Google Scholar
• Nanovskaya TN , Oncken C , Fokina VM , et al. Bupropion sustained release for pregnant smokers: a randomized, placebo-controlled trial. Am J Obstet Gynecol. 2017 Apr;216(4):420.e1–420.e9.
   PubMed Web of Science ®Google Scholar
• Stotts AL , Northrup TF , Cinciripini PM , et al. Randomized, controlled pilot trial of bupropion for pregnant smokers: challenges and future directions. Am J Perinatol. 2015 Mar;32(4):351–356.
   PubMed Web of Science ®Google Scholar
• Cahill K , Lindson-Hawley N , Thomas KH , et al. Nicotine receptor partial agonists for smoking cessation. Cochrane Database Syst Rev. 2016 May;9(5):CD006103.
   Google Scholar
• Anthenelli RM , Benowitz NL , West R , et al. Neuropsychiatric safety and efficacy of varenicline, bupropion, and nicotine patch in smokers with and without psychiatric disorders (EAGLES): a double-blind, randomised, placebo-controlled clinical trial. Lancet. 2016 Jun 18;387(10037):2507–2520.
   PubMed Web of Science ®Google Scholar
• Harrison-Woolrych M , Paterson H , Tan M . Exposure to the smoking cessation medicine varenicline during pregnancy: a prospective nationwide cohort study. Pharmacoepidemiol Drug Saf. 2013 Oct;22(10):1086–1092.
   PubMed Web of Science ®Google Scholar
• Olsen M , Petronis KR , Froslev T , et al. Maternal use of varenicline and risk of congenital malformations. Pharmacoepidemiol Drug Saf. 2015 SEP;24(1):244.
   Google Scholar
• Richardson JL , Stephens S , Yates LM , et al. Pregnancy outcomes after maternal varenicline use; analysis of surveillance data collected by the European Network of Teratology Information Services. Reprod Toxicol. 2017;67:26–34.
   PubMed Web of Science ®Google Scholar
• Bibbins-Domingo K , Grossman DC , et al.; US Preventive Services Task Force . Primary care interventions to support breastfeeding: US Preventive Services Task ForceRecommendation Statement. JAMA. 2016 Oct 25;316(16):1688–1693.
   PubMed Web of Science ®Google Scholar
• Napierala M , Mazela J , Merritt TA , et al. Tobacco smoking and breastfeeding: effect on the lactation process, breast milk composition and infant development. A Critical Review. Environ Res. 2016;151:321–338.
   PubMed Web of Science ®Google Scholar
• Dorea JG . Maternal smoking and infant feeding: breastfeeding is better and safer. Matern Child Health J. 2007 May;11(3):287–291.
   PubMed Web of Science ®Google Scholar
• Sachs HC; Committee On Drugs . The transfer of drugs and therapeutics into human breast milk: an update on selected topics. Pediatrics. 2013 Sep;132(3):e796–e809.
   PubMed Web of Science ®Google Scholar
• Anon . Varenicline and bupropion. Reports of suicidality associated with used of varenicline (marketed as CHANTIX) and bupropion (marketed as Zyban and generics). FDA Drug Saf Newsl. 2009;2(1):1–4.
   Google Scholar
• U.S. Food and Drug Administration . FDA Drug Safety Communication: FDA revises description of mental health side effects of the stop-smoking medicines Chantix (varenicline) and Zyban (bupropion) to reflect clinical trial findings. 3 March 2018. [cited 2018 May]. Available from: https://www.fda.gov/Drugs/DrugSafety/ucm532221.htm.
   Google Scholar
• Flick LH , Cook CA , Homan SM , et al. Persistent tobacco use during pregnancy and the likelihood of psychiatric disorders. Am J Public Health. 2006 Oct;96(10):1799–1807.
   PubMed Web of Science ®Google Scholar
• Paschetta E , Berrisford G , Coccia F , et al. Perinatal psychiatric disorders: an overview. Am J Obstet Gynecol. 2014 Jun;210(6):501–509.e6.
   PubMed Web of Science ®Google Scholar
• U.S. Food and Drug Administration . Chantix (varenicline): safety communication—updated safety review on the risk of cardiovascular adverse events. 12 December 2012. [cited 2018 May 8]. Available from: www.fda.gov
   Google Scholar
• Barboza JL , Patel R , Patel P , et al. An update on the pharmacotherapeutic interventions for smoking cessation. Expert Opin Pharmacother. 2016 Aug;17(11):1483–1496.
   PubMed Web of Science ®Google Scholar
• Benowitz NL , Pipe A , West R , et al. Cardiovascular safety of varenicline, bupropion, and nicotine patch in smokers: a randomized clinical trial. JAMA Intern Med. 2018 May 1;178(5):622–631.
   PubMed Web of Science ®Google Scholar
• Bakker H , Jaddoe VW . Cardiovascular and metabolic influences of fetal smoke exposure. Eur J Epidemiol. 2011 Oct;26(10): 763–770.
   PubMed Web of Science ®Google Scholar
• Centers for Disease Control and Prevention. Electronic Cigarettes. Updated May 16, 2018. [cited 2018 May 17]. Available from: https://www.cdc.gov/tobacco/basic_information/e-cigarettes/index.htm
   Google Scholar
• McNeill A , Brose LS , Calder R , et al. Evidence review of e-cigarettes and heated tobacco products: a report commissioned by Public Health England. London: Stationery Office, 2018. [cited 2018 May 17]. Available from: https://www.gov.uk/government/publications/e-cigarettes-and-heated-tobacco-products-evidence-review
   Google Scholar
• Oncken C , Ricci KA , Kuo CL , et al. Correlates of electronic cigarettes use before and during pregnancy. Nicotine Tob Res. 2017 May 1;19(5):585–590.
   PubMed Web of Science ®Google Scholar
• Kurti AN , Redner R , Lopez AA , et al. Tobacco and nicotine delivery product use in a national sample of pregnant women. Prev Med. 2017;104:50–56.
   PubMed Web of Science ®Google Scholar
• Kalkhoran S , Glantz SA . E-cigarettes and smoking cessation in real-world and clinical settings: a systematic review and meta-analysis. Lancet Respir Med. 2016 Feb;4(2):116–128.
   PubMed Web of Science ®Google Scholar
• McRobbie H , Bullen C , Hartmann-Boyce J , et al. Electronic cigarettes for smoking cessation and reduction. Cochrane Database Syst Rev. 2014;(12):CD010216. doi: 10.1002/14651858.CD010216.pub2. Epub 2014 Dec 17.
   PubMed Web of Science ®Google Scholar
• British Medical Association . E-cigarettes: balancing risks and opportunities. London: British Medical Association; 2017.
   Google Scholar
• WHO Framework Convention of Tobacco Control . Electronic Nicotine Delivery Systems and Electronic Non-Nicotine Delivery Systems (ENDS/ENNDS) Report by WHO. Conference of the Parties to the WHO Framework Convention on Tobacco Control. Seventh Session. Delhi, India, 7–12 November 2016. [cited 2018 Sep]. Available from: http://www.who.int/fctc/cop/cop7/FCTC_COP_7_11_EN.pdf?ua=1
   Google Scholar
• Singh S , Sedgh G , Hussain R . Unintended pregnancy: worldwide levels, trends, and outcomes. Stud Fam Plann. 2010 Dec;41(4):241–250.
   PubMed Web of Science ®Google Scholar
• Kranzler HR Placebo-controlled trial of bupropion for smoking cessation in pregnant women. British Medical Association. E-cigarettes: balancing risks and opportunities. London: British Medical Association, 2017. ClinicalTrials.gov. [cited 2018 May]. Available from: https://clinicaltrials.gov/ct2/show/NCT02188459
   Google Scholar
• Karam-Hage M , Kypriotakis G , Robinson JD , et al. Improvement of smoking abstinence rates with increased varenicline dosage: a propensity score-matched analysis. J Clin Psychopharmacol. 2018 Feb;38(1):34–41.
   PubMed Web of Science ®Google Scholar