Drug treatment of chronic subdural hematoma

References

• Brennan PM, Kolias AG, Joannides AJ, et al. The management and outcome for patients with chronic subdural hematoma: a prospective, multicenter, observational cohort study in the United Kingdom. J Neurosurg. 2017 Oct;127(4):732–739.
   PubMed Web of Science ®Google Scholar
• Kudo H, Kuwamura K, Izawa I, et al. Chronic subdural hematoma in elderly people: present status on Awaji Island and epidemiological prospect. Neurol Med Chir (Tokyo). 1992 Apr;32(4):207–209.
   PubMedGoogle Scholar
• Huang J, Li L, Zhang J, et al. Treatment of relapsed chronic subdural hematoma in four young children with atorvastatin and low-dose dexamethasone. Pharmacotherapy. 2019 Jul;39(7):783–789.
   PubMed Web of Science ®Google Scholar
• Wu X, Li G, Zhao J, et al. Arachnoid cyst-associated chronic subdural hematoma: report of 14 cases and a systematic literature review. World Neurosurg. 2018 Jan;109:e118–e30.
   PubMed Web of Science ®Google Scholar
• Fang J, Liu Y, Jiang X. Ossified chronic subdural hematoma in children: Case Report and Review of Literature. World Neurosurg. 2019 Jun;126:613–615.
   Google Scholar
• Domenicucci M, Russo N, Giugni E, et al. Relationship between supratentorial arachnoid cyst and chronic subdural hematoma: neuroradiological evidence and surgical treatment. J Neurosurg. 2009 Jun;110(6):1250–1255.
   PubMed Web of Science ®Google Scholar
• Kolias AG, Chari A, Santarius T, et al. Chronic subdural haematoma: modern management and emerging therapies. Nat Rev Neurol. 2014 Oct;10(10):570–578.
   PubMed Web of Science ®Google Scholar
• Wang D, Li T, Tian Y, et al. Effects of atorvastatin on chronic subdural hematoma: a preliminary report from three medical centers. J Neurol Sci. 2014 Jan 15;336(1–2):237–242.
   PubMed Web of Science ®Google Scholar
• Jiang R, Zhao S, Wang R, et al. Safety and efficacy of atorvastatin for chronic subdural hematoma in chinese patients: a randomized clinical trial. JAMA Neurol. 2018 Nov 1;75(11):1338–1346.
   PubMed Web of Science ®Google Scholar
• Tseng J-H, Tseng M-Y, Liu A-J, et al. Risk factors for chronic subdural hematoma after a minor head injury in the elderly: a population-based study. Biomed Res Int. 2014;2014:218646.
   PubMedGoogle Scholar
• Lee K-S. History of Chronic Subdural Hematoma. Korean J Neurotrauma. 2015 Oct;11(2):27–34.
   PubMedGoogle Scholar
• Edlmann E, Giorgi-Coll S, Whitfield PC, et al. Pathophysiology of chronic subdural haematoma: inflammation, angiogenesis and implications for pharmacotherapy. J Neuroinflammation. 2017 May 30; 14(1):108.
   PubMedGoogle Scholar
• Nakamura S, Tsubokawa T. Extraction of angiogenesis factor from chronic subdural haematomas. Significance in capsule formation and haematoma growth. Brain Inj. 1989 Apr-Jun;3(2):129–136.
   PubMedGoogle Scholar
• Weigel R, Schilling L, Schmiedek P. Specific pattern of growth factor distribution in chronic subdural hematoma (CSH): evidence for an angiogenic disease. Acta Neurochir (Wien). 2001 Aug;143(8):811–818. discussion 19.
   PubMed Web of Science ®Google Scholar
• Hohenstein A, Erber R, Schilling L, et al. Increased mRNA expression of VEGF within the hematoma and imbalance of angiopoietin-1 and −2 mRNA within the neomembranes of chronic subdural hematoma. J Neurotrauma. 2005 May;22(5):518–528.
   PubMed Web of Science ®Google Scholar
• Frati A, Salvati M, Mainiero F, et al. Inflammation markers and risk factors for recurrence in 35 patients with a posttraumatic chronic subdural hematoma: a prospective study. J Neurosurg. 2004 Jan;100(1):24–32.
   PubMed Web of Science ®Google Scholar
• Ito H, Yamamoto S, Komai T, et al. Role of local hyperfibrinolysis in the etiology of chronic subdural hematoma. J Neurosurg. 1976 Jul;45(1):26–31.
   PubMed Web of Science ®Google Scholar
• Winn HR. Youmans & Winn Neurological Surgery. New York, NY: Elsevier; 2017. 7th ed.
   Google Scholar
• Lee KS. How to Treat Chronic Subdural Hematoma? Past and Now. J Korean Neurosurg Soc. 2019 Mar;62(2):144–152.
   PubMed Web of Science ®Google Scholar
• Thomas PAW, Mitchell PS, Marshman LAG. Early postoperative morbidity after chronic subdural hematoma: predictive usefulness of the physiological and operative severity score for enumeration of mortality and morbidity, american college of surgeons national surgical quality improvement program, and american society of anesthesiologists grade in a prospective cohort. World Neurosurg. 2019 Jan 3;pii: S1878-8750(18)32942-5.
   Web of Science ®Google Scholar
• Aukland K, Reed RK. Interstitial-lymphatic mechanisms in the control of extracellular fluid volume. Physiol Rev. 1993 Jan;73(1):1–78.
   PubMed Web of Science ®Google Scholar
• Delgado-Lopez PD, Martin-Velasco V, Castilla-Diez JM, et al. Dexamethasone treatment in chronic subdural haematoma. Neurocirugia (Astur). 2009 Aug;20(4):346–359.
   PubMed Web of Science ®Google Scholar
• Vaquero J, Zurita M, Cincu R. Vascular endothelial growth-permeability factor in granulation tissue of chronic subdural haematomas. Acta Neurochir (Wien). 2002 Apr;144(4):343–346. discussion 47.
   PubMed Web of Science ®Google Scholar
• Suzuki K, Takano S, Nose T,M, et al. Increased concentration of vascular endothelial growth factor (VEGF) in chronic subdural hematoma. J Trauma. 1999 Mar;46(3):532–533.
   PubMedGoogle Scholar
• Hong HJ, Kim YJ, Yi HJ, et al. Role of angiogenic growth factors and inflammatory cytokine on recurrence of chronic subdural hematoma. Surg Neurol. 2009 Feb;71(2):161–165. discussion 65-6.
   PubMedGoogle Scholar
• Yoo SA, Yoon HJ, Kim HS, et al. Role of placenta growth factor and its receptor flt-1 in rheumatoid inflammation: a link between angiogenesis and inflammation. Arthritis Rheum. 2009 Feb;60(2):345–354.
   PubMedGoogle Scholar
• Kalamatianos T, Stavrinou LC, Koutsarnakis C, et al. and sVEGFR-1 in chronic subdural hematoma: implications for hematoma development. J Neurosurg. 2013 Feb;118(2):353–357.
   PubMed Web of Science ®Google Scholar
• Fischer C, Jonckx B, Mazzone M, et al. Anti-PlGF inhibits growth of VEGF(R)-inhibitor-resistant tumors without affecting healthy vessels. Cell. 2007 Nov 2;131(3):463–475.
   PubMed Web of Science ®Google Scholar
• Autiero M, Waltenberger J, Communi D, et al. Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1. Nat Med. 2003 Jul;9(7):936–943.
   PubMed Web of Science ®Google Scholar
• Li B, Mahmood A, Lu D, et al. Simvastatin attenuates microglial cells and astrocyte activation and decreases interleukin-1beta level after traumatic brain injury. Neurosurgery. 2009 Jul;65(1):179–185. discussion 85-6.
   PubMed Web of Science ®Google Scholar
• Isidori AM, Venneri MA, Fiore D. Angiopoietin-1 and Angiopoietin-2 in metabolic disorders: therapeutic strategies to restore the highs and lows of angiogenesis in diabetes. J Endocrinol Invest. 2016 Nov;39(11):1235–1246.
   PubMed Web of Science ®Google Scholar
• Thomas M, Kienast Y, Scheuer W, et al. A novel angiopoietin-2 selective fully human antibody with potent anti-tumoral and anti-angiogenic efficacy and superior side effect profile compared to Pan-Angiopoietin-1/-2 inhibitors. PloS One. 2013;8(2):e54923.
   PubMed Web of Science ®Google Scholar
• Zhou HJ, Tang T, Cui HJ, et al. Thrombin-triggered angiogenesis in rat brains following experimental intracerebral hemorrhage. J Neurosurg. 2012 Nov;117(5):920–928.
   PubMed Web of Science ®Google Scholar
• Song Y, Wang Z, Liu L, et al. The level of circulating endothelial progenitor cells may be associated with the occurrence and recurrence of chronic subdural hematoma. Clinics (Sao Paulo). 2013;68(8):1084–1088.
   PubMed Web of Science ®Google Scholar
• Stanisic M, Aasen AO, Pripp AH, et al. Local and systemic pro-inflammatory and anti-inflammatory cytokine patterns in patients with chronic subdural hematoma: a prospective study. Inflamm Res. 2012 Aug;61(8):845–852.
   PubMed Web of Science ®Google Scholar
• Premack BA, Schall TJ. Chemokine receptors: gateways to inflammation and infection. Nat Med. 1996 Nov;2(11):1174–1178.
   PubMed Web of Science ®Google Scholar
• Li W, Lin S, Li W, et al. IL-8 interacts with metadherin promoting proliferation and migration in gastric cancer. Biochem Biophys Res Commun. 2016 Sep 23;478(3):1330–1337.
   PubMed Web of Science ®Google Scholar
• Long X, Ye Y, Zhang L, et al. IL-8, a novel messenger to cross-link inflammation and tumor EMT via autocrine and paracrine pathways (Review). Int J Oncol. 2016 Jan;48(1):5–12.
   PubMed Web of Science ®Google Scholar
• Conroy S, Kruyt FAE, Wagemakers M, et al. IL-8 associates with a pro-angiogenic and mesenchymal subtype in glioblastoma. Oncotarget. 2018 Mar 20;9(21):15721–15731.
   PubMedGoogle Scholar
• Ouyang W, Rutz S, Crellin NK, et al. Regulation and functions of the IL-10 family of cytokines in inflammation and disease. Annu Rev Immunol. 2011;29:71–109.
   PubMed Web of Science ®Google Scholar
• Moore KW, de Waal Malefyt R, Coffman RL, et al. Interleukin-10 and the interleukin-10 receptor. Annu Rev Immunol. 2001;19:683–765.
   PubMed Web of Science ®Google Scholar
• Quan W, Zhang Z, Tian Q, et al. A rat model of chronic subdural hematoma: insight into mechanisms of revascularization and inflammation. Brain Res. 2015 Nov;2(1625):84–96.
   Google Scholar
• Quan W, Zhang Z, Li P, et al. Role of regulatory Tcells in atorvastatin induced absorption of chronic subdural hematoma in rats. Aging Dis. 2019 Oct;10(5):992-1002.
   Google Scholar
• Apfelbaum RI, Guthkelch AN, Shulman K. Experimental production of subdural hematomas. J Neurosurg. 1974 Mar;40(3):336–346.
   PubMed Web of Science ®Google Scholar
• Manickam A, Marshman LAG, Johnston R, et al. Mathematical formulae to estimate chronic subdural haematoma volume. Flawed assumption regarding ellipsoid morphology. J Clin Neurosci. 2017 Jun;40:39–43.
   PubMed Web of Science ®Google Scholar
• Heula AL, Ohlmeier S, Sajanti J, et al. Characterization of chronic subdural hematoma fluid proteome. Neurosurgery. 2013 Aug;73(2):317–331.
   PubMed Web of Science ®Google Scholar
• Nomura S, Kashiwagi S, Fujisawa H, et al. Characterization of local hyperfibrinolysis in chronic subdural hematomas by SDS-PAGE and immunoblot. J Neurosurg. 1994 Dec;81(6):910–913.
   PubMed Web of Science ®Google Scholar
• Krittalak K, Sawanyawisuth K, Tiamkao S. Safety of withholding anticoagulation in patients with mechanical prosthetic valves and intracranial haemorrhage. Intern Med J. 2011 Oct;41(10):750–754.
   PubMed Web of Science ®Google Scholar
• Romero Lopez J, Macineiras Montero JL, Fontanillo Fontanillo M, et al. Lobar intracerebral haemorrhage: analysis of a series and characteristics of patients receiving antiplatelet or anticoagulation treatment. Neurologia. 2012 Sep;27(7):387–393.
   PubMed Web of Science ®Google Scholar
• Bakker-Arkema RG, Davidson MH, Goldstein RJ, et al. Efficacy and safety of a new HMG-CoA reductase inhibitor, atorvastatin, in patients with hypertriglyceridemia. JAMA. 1996 Jan 10;275(2):128–133.
   PubMed Web of Science ®Google Scholar
• Nissen SE, Nicholls SJ, Sipahi I, et al. Effect of very high-intensity statin therapy on regression of coronary atherosclerosis: the ASTEROID trial. JAMA. 2006 Apr 5;295(13):1556–1565.
   PubMed Web of Science ®Google Scholar
• Goldstein JL, Brown MS. A century of cholesterol and coronaries: from plaques to genes to statins. Cell. 2015 Mar 26;161(1):161–172.
   PubMed Web of Science ®Google Scholar
• Pocathikorn A, Taylor RR, Mamotte CD. Atorvastatin increases expression of low-density lipoprotein receptor mRNA in human circulating mononuclear cells. Clin Exp Pharmacol Physiol. 2010 Apr;37(4):471–476.
   PubMed Web of Science ®Google Scholar
• Youssef S, Stuve O, Patarroyo JC, et al. The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease. Nature. 2002 Nov 7;420(6911):78–84.
   PubMed Web of Science ®Google Scholar
• Wang B, Sun L, Tian Y, et al. Effects of atorvastatin in the regulation of circulating EPCs and angiogenesis in traumatic brain injury in rats. J Neurol Sci. 2012 Aug 15;319(1–2):117–123.
   PubMed Web of Science ®Google Scholar
• Li Z, Wang B, Kan Z, et al. Progesterone increases circulating endothelial progenitor cells and induces neural regeneration after traumatic brain injury in aged rats. J Neurotrauma. 2012 Jan 20;29(2):343–353.
   PubMed Web of Science ®Google Scholar
• Araujo FA, Rocha MA, Mendes JB, et al. Atorvastatin inhibits inflammatory angiogenesis in mice through down regulation of VEGF, TNF-alpha and TGF-beta1. Biomed Pharmacother. 2010 Jan;64(1):29–34.
   PubMed Web of Science ®Google Scholar
• Li T, Wang D, Tian Y, et al. Effects of atorvastatin on the inflammation regulation and elimination of subdural hematoma in rats. J Neurol Sci. 2014 Jun 15;341(1–2):88–96.
   PubMed Web of Science ®Google Scholar
• Jiang R, Wang D, Poon WS, et al. Effect of ATorvastatin On Chronic subdural Hematoma (ATOCH): a study protocol for a randomized controlled trial. Trials. 2015 Nov;18(16):528.
   Google Scholar
• Xu M, Chen P, Zhu X, et al. Effects of atorvastatin on conservative and surgical treatments of chronic subdural hematoma in patients. World Neurosurg. 2016 Jul;91:23–28.
   PubMed Web of Science ®Google Scholar
• Tang R, Shi J, Li X, et al. Effects of atorvastatin on surgical treatments of chronic subdural hematoma. World Neurosurg. 2018;117:e425–e29.
   PubMed Web of Science ®Google Scholar
• Huang J, Tian Y, Song Y, et al. Effect of different factors on the short-term outcome of chinese patients with primary chronic subdural hematoma at different age groups: A two-center retrospective study. Front Aging Neurosci. 2019;11:325.
   PubMed Web of Science ®Google Scholar
• Corsini A, Bellosta S, Davidson MH. Pharmacokinetic interactions between statins and fibrates. Am J Cardiol. 2005 Nov 7;96(9a):44K–49K. discussion 34K-35K.
   PubMed Web of Science ®Google Scholar
• Gonzalez Santos P. [The combinations of statins and fibrates: pharmacokinetic and clinical implications]. Clin Investig Arterioscler. 2014 Jul;26(Suppl 1):7–11.
   PubMedGoogle Scholar
• Kido K, Wheeler MB, Seratnahaei A, et al. Rhabdomyolysis precipitated by possible interaction of ticagrelor with high-dose atorvastatin. J Am Pharm Assoc (2003). 2015 May-Jun;55(3):320–323.
   PubMed Web of Science ®Google Scholar
• Beavers JC. Elevated creatine kinase due to potential drug interaction with ticagrelor and atorvastatin. J Pharm Pract. 2019 Feb;32(1):106–108.
   PubMed Web of Science ®Google Scholar
• Hsiao SH, Chang HJ, Hsieh TH, et al. Rhabdomyolysis caused by the moderate CYP3A4 inhibitor fluconazole in a patient on stable atorvastatin therapy: a case report and literature review. J Clin Pharm Ther. 2016 Oct;41(5):575–578.
   PubMed Web of Science ®Google Scholar
• Ambrosetto C. Post-traumatic subdural hematoma. Further observations on nonsurgical treatment. Arch Neurol. 1962 Apr;6:287–292.
   PubMedGoogle Scholar
• Bender MB, Christoff N. Nonsurgical treatment of subdural hematomas. Arch Neurol. 1974 Aug;31(2):73–79.
   PubMedGoogle Scholar
• Holl DC, Volovici V, Dirven CMF, et al. Pathophysiology and nonsurgical treatment of chronic subdural hematoma: from past to present to future. World Neurosurg. 2018 Aug;116(402–11):e2.
   Google Scholar
• Emich S, Richling B, McCoy MR, Al-Schameri RA, Ling F, Sun L, et al. The efficacy of dexamethasone on reduction in the reoperation rate of chronic subdural hematoma–the DRESH study: straightforward study protocol for a randomized controlled trial. Trials. 2014 Jan;6(15):6.
   Google Scholar
• Baschera D, Tosic L, Westermann L, et al. Treatment standards for chronic subdural hematoma: Results from a survey in Austrian, German, and Swiss Neurosurgical Units. World Neurosurg. 2018 Aug;116:e983–e95.
   PubMed Web of Science ®Google Scholar
• Berghauser Pont LM, Dammers R, Schouten JW, et al. Clinical factors associated with outcome in chronic subdural hematoma: a retrospective cohort study of patients on preoperative corticosteroid therapy. Neurosurgery. 2012 Apr;70(4):873–880. discussion 80.
   PubMed Web of Science ®Google Scholar
• Dran G, Berthier F, Fontaine D, et al. [Effectiveness of adjuvant corticosteroid therapy for chronic subdural hematoma: a retrospective study of 198 cases]. Neurochirurgie. 2007 Dec;53(6):477–482.
   PubMed Web of Science ®Google Scholar
• Berghauser Pont LM, Dirven CM, Dippel DW, et al. The role of corticosteroids in the management of chronic subdural hematoma: a systematic review. Eur J Neurol. 2012 Nov;19(11):1397–1403.
   PubMed Web of Science ®Google Scholar
• Chan DYC, Sun TFD, Poon WS. Steroid for chronic subdural hematoma? A prospective phase IIB pilot randomized controlled trial on the use of dexamethasone with surgical drainage for the reduction of recurrence with reoperation. Chin Neurosurg J. 2015 August 18;1(1):2.
   Google Scholar
• Mebberson K, Colditz M, Marshman LAG, et al. Prospective randomized placebo-controlled double-blind clinical study of adjuvant dexamethasone with surgery for chronic subdural haematoma with post-operative subdural drainage: interim analysis. J Clin Neurosci. 2019 Sep 3;pii: S0967-5868(19)31364-5.
   PubMed Web of Science ®Google Scholar
• Kolias AG, Edlmann E, Thelin EP, et al. Dexamethasone for adult patients with a symptomatic chronic subdural haematoma (Dex-CSDH) trial: study protocol for a randomised controlled trial. Trials. 2018 Dec 4;19(1):670.
   PubMedGoogle Scholar
• Miah IP, Holl DC, Peul WC, et al. Dexamethasone therapy versus surgery for chronic subdural haematoma (DECSA trial): study protocol for a randomised controlled trial. Trials. 2018 Oct 20;19(1):575.
   PubMedGoogle Scholar
• Henaux PL, Le Reste PJ, Laviolle B, et al. Steroids in chronic subdural hematomas (SUCRE trial): study protocol for a randomized controlled trial. Trials. 2017 Jun 5;18(1):252.
   PubMedGoogle Scholar
• Hazlewood KA, Fugate SE, Harrison DL. Effect of oral corticosteroids on chronic warfarin therapy. Ann Pharmacother. 2006 Dec;40(12):2101–2106.
   PubMed Web of Science ®Google Scholar
• Kremers E, Urdang G, Sonnedecker G. Kremers and Urdang’s History of Pharmacy. Madison, WI: American Institute of the History of Pharmacy; 1986.
   Google Scholar
• Witherspoon B, Ashby NE. The use of mannitol and hypertonic saline therapies in patients with elevated intracranial pressure: A review of the evidence. Nurs Clin North Am. 2017 Jun;52(2):249–260.
   PubMed Web of Science ®Google Scholar
• GARDNER WJ. TRAUMATIC SUBDURAL HEMATOMA. WITH PARTICULAR REFERENCE TO THE LATENT INTERVAL. Arch Neurol Psychiatry. 1932;27(4):847–858.
   Google Scholar
• Suzuki J, Takaku A. Nonsurgical treatment of chronic subdural hematoma. J Neurosurg. 1970 Nov;33(5):548–553.
   PubMed Web of Science ®Google Scholar
• Gjerris F, Schmidt K. Chronic subdural hematoma. Surgery or mannitol treatment. J Neurosurg. 1974 May;40(5):639–642.
   PubMed Web of Science ®Google Scholar
• Thomas PAW, Marshman LAG, Rudd D, et al. Growth and resorption of chronic subdural hematomas: Gardner, weir, and the osmotic hypothesis revisited. World Neurosurg. 2019 Dec;132:e202–e07.
   PubMed Web of Science ®Google Scholar
• Logan JW. Diet and free radicals in cot death. N Z Med J. 1990 Dec 12;103(903):592.
   PubMed Web of Science ®Google Scholar
• Coates D. The angiotensin converting enzyme (ACE). Int J Biochem Cell Biol. 2003 Jun;35(6):769–773.
   PubMed Web of Science ®Google Scholar
• Khakoo AY, Sidman RL, Pasqualini R, et al. Does the renin-angiotensin system participate in regulation of human vasculogenesis and angiogenesis? Cancer Res. 2008 Nov 15;68(22):9112–9115.
   PubMed Web of Science ®Google Scholar
• Zambidis ET, Park TS, Yu W, et al. Expression of angiotensin-converting enzyme (CD143) identifies and regulates primitive hemangioblasts derived from human pluripotent stem cells. Blood. 2008 Nov 1;112(9):3601–3614.
   PubMed Web of Science ®Google Scholar
• Aiello LP, Avery RL, Arrigg PG, et al. Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders. N Engl J Med. 1994 Dec 1;331(22):1480–1487.
   PubMed Web of Science ®Google Scholar
• Chaturvedi N, Sjolie AK, Stephenson JM, et al. Effect of lisinopril on progression of retinopathy in normotensive people with type 1 diabetes. The EUCLID Study Group. EURODIAB Controlled Trial of Lisinopril in Insulin-Dependent Diabetes Mellitus. Lancet. 1998 Jan 3;351(9095):28–31.
   PubMed Web of Science ®Google Scholar
• Gilbert RE, Kelly DJ, Cox AJ, et al. Angiotensin converting enzyme inhibition reduces retinal overexpression of vascular endothelial growth factor and hyperpermeability in experimental diabetes. Diabetologia. 2000 Nov;43(11):1360–1367.
   PubMed Web of Science ®Google Scholar
• Weigel R, Hohenstein A, Schlickum L, et al. Angiotensin converting enzyme inhibition for arterial hypertension reduces the risk of recurrence in patients with chronic subdural hematoma possibly by an antiangiogenic mechanism. Neurosurgery. 2007 Oct;61(4):788–792. discussion 92-3.
   PubMed Web of Science ®Google Scholar
• Bartek J Jr., Sjavik K, Schaible S, et al. The role of angiotensin-converting enzyme inhibitors in patients with chronic subdural hematoma: A scandinavian population-based multicenter study. World Neurosurg. 2018;113:e555–e60.
   PubMed Web of Science ®Google Scholar
• Neidert MC, Schmidt T, Mitova T, et al. Preoperative angiotensin converting enzyme inhibitor usage in patients with chronic subdural hematoma: associations with initial presentation and clinical outcome. J Clin Neurosci. 2016;28:82–86.
   PubMed Web of Science ®Google Scholar
• Poulsen FR, Munthe S, Soe M, et al. Perindopril and residual chronic subdural hematoma volumes six weeks after burr hole surgery: a randomized trial. Clin Neurol Neurosurg. 2014 Aug;123:4–8.
   PubMed Web of Science ®Google Scholar
• Kostis WJ, Shetty M, Chowdhury YS, et al. a Review. Curr Hypertens Rep. 2018 Jun 8;20(7):55.
   PubMed Web of Science ®Google Scholar
• Dendorfer A, Wolfrum S, Wagemann M, et al. Pathways of bradykinin degradation in blood and plasma of normotensive and hypertensive rats. Am J Physiol Heart Circ Physiol. 2001 May;280(5):H2182–8.
   PubMed Web of Science ®Google Scholar
• Moskowitz R. The angiotensin-converting enzyme inhibitor and aspirin interaction in congestive heart failure: fear or reality? Curr Cardiol Rep. 2001 May;3(3):247–253.
   PubMedGoogle Scholar
• Ahmed A. Interaction between aspirin and angiotensin-converting enzyme inhibitors: should they be used together in older adults with heart failure? J Am Geriatr Soc. 2002 Jul;50(7):1293–1296.
   PubMed Web of Science ®Google Scholar
• Barbash IM, Goldbourt U, Gottlieb S, et al. Possible interaction between aspirin and ACE inhibitors: update on unresolved controversy. Congest Heart Fail. 2000 Nov-Dec;6(6):313–318.
   PubMedGoogle Scholar
• Dunn CJ, Goa KL. Tranexamic Acid. Drugs. 1999 June 01;57(6):1005–1032.
   PubMed Web of Science ®Google Scholar
• Ng W, Jerath A, Wasowicz M. Tranexamic acid: a clinical review. Anaesthesiol Intensive Ther. 2015;47(4):339–350.
   PubMed Web of Science ®Google Scholar
• collaborators C-T, Shakur H, Roberts I, et al. Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial. Lancet. 2010 Jul 3;376(9734):23–32.
   PubMed Web of Science ®Google Scholar
• collaborators C-t. Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3). Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomised, placebo-controlled trial. Lancet. 2019 Nov 9;394(10210):1713–1723.
   PubMed Web of Science ®Google Scholar
• Kageyama H, Toyooka T, Tsuzuki N, et al. Nonsurgical treatment of chronic subdural hematoma with tranexamic acid. J Neurosurg. 2013 Aug;119(2):332–337.
   PubMed Web of Science ®Google Scholar
• Mikkelsen R, Anker-Moller T, Hvas A-M, et al. A case of tranexamic acid as adjunctive treatment for chronic subdural hematoma with multiple recurrences. Am J Case Rep. 2017 Sep 18;18:995–999.
   PubMed Web of Science ®Google Scholar
• Moscote-Salazar LR, Satyarthee GD, Matus JA, et al. Conservative management of chronic subdural hematoma with tranexamic acid. Asian J Neurosurg. 2018 Jul-Sep;13(3):951–952.
   PubMedGoogle Scholar
• Hall S, Walshe E, Ajayi C, et al. Acute-on-chronic subdural hematoma in a patient taking Red Clover herbal supplement: A case report. Surg Neurol Int. 2018;9:43.
   PubMedGoogle Scholar
• Kutty RK, Peethambaran AK, Sunilkumar S. Conservative treatment of chronic subdural hematoma in HIV-associated thrombocytopenia with tranexamic acid. J Int Assoc Provid AIDS Care. 2017 May;16(3):211–214.
   PubMedGoogle Scholar
• Roberts I, Perel P, Prieto-Merino D, et al. Effect of tranexamic acid on mortality in patients with traumatic bleeding: prespecified analysis of data from randomised controlled trial. BMJ. 2012;345:e5839.
   PubMedGoogle Scholar
• Rozen L, Faraoni D, Sanchez Torres C, et al. Effective tranexamic acid concentration for 95% inhibition of tissue-type plasminogen activator induced hyperfibrinolysis in children with congenital heart disease: A prospective, controlled, in-vitro study. Eur J Anaesthesiol. 2015 Dec;32(12):844–850.
   PubMed Web of Science ®Google Scholar
• Muthialu N, Balakrishnan S, Sundar R, et al. Efficacy of tranexamic acid as compared to aprotinin in open heart surgery in children. Ann Card Anaesth. 2015 Jan-Mar;18(1):23–26.
   PubMedGoogle Scholar
• Nishijima DK, VanBuren J, Hewes HA, et al. Traumatic injury clinical trial evaluating tranexamic acid in children (TIC-TOC): study protocol for a pilot randomized controlled trial. Trials. 2018 Oct 30;19(1):593.
   PubMedGoogle Scholar
• Fenger-Eriksen C, D’Amore Lindholm A, Norholt SE, et al. Reduced perioperative blood loss in children undergoing craniosynostosis surgery using prolonged tranexamic acid infusion: a randomised trial. Br J Anaesth. 2019 Jun;122(6):760–766.
   PubMed Web of Science ®Google Scholar
• Tang C, Dong X, He W, et al. Cerebral mechanism of celecoxib for treating knee pain: study protocol for a randomized controlled parallel trial. Trials. 2019 Jan 16;20(1):58.
   PubMedGoogle Scholar
• Isola G, Matarese M, Ramaglia L, et al. Evaluation of the efficacy of celecoxib and ibuprofen on postoperative pain, swelling, and mouth opening after surgical removal of impacted third molars: a randomized, controlled clinical trial. International Journal of Oral and Maxillofacial Surgery. 2019 Mar 7;48:1348–1354.
   Web of Science ®Google Scholar
• Bombardier C, Laine L, Reicin A, et al. Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. N Engl J Med. 2000 Nov 23;343(21):1520–1528. 2 p following 28
   PubMed Web of Science ®Google Scholar
• Hara M, Tamaki M, Aoyagi M, et al. Possible role of cyclooxygenase-2 in developing chronic subdural hematoma. J Med Dent Sci. 2009 Sep;56(3):101–106.
   PubMedGoogle Scholar
• Schaumann A, Klene W, Rosenstengel C, et al. COXIBRAIN: results of the prospective, randomised, phase II/III study for the selective COX-2 inhibition in chronic subdural haematoma patients. Acta Neurochir (Wien). 2016 Nov;158(11):2039–2044.
   PubMed Web of Science ®Google Scholar
• Friess SH, Naim MY, Kilbaugh TJ, et al. Premedication with meloxicam exacerbates intracranial haemorrhage in an immature swine model of non-impact inertial head injury. Lab Anim. 2012 Apr;46(2):164–166.
   PubMedGoogle Scholar
• Mersfelder TL, Stewart LR. Warfarin and celecoxib interaction. Ann Pharmacother. 2000 Mar;34(3):325–327.
   PubMed Web of Science ®Google Scholar
• Schaefer MG, Plowman BK, Morreale AP, et al. Interaction of rofecoxib and celecoxib with warfarin. Am J Health Syst Pharm. 2003 Jul 1;60(13):1319–1323.
   PubMed Web of Science ®Google Scholar
• Fisher AA, Le Couteur DG. Intracerebral hemorrhage following possible interaction between celecoxib and clopidogrel. Ann Pharmacother. 2001 Dec;35(12):1567–1569.
   PubMed Web of Science ®Google Scholar
• Ramirez J, House LK, Karrison TG, et al. Prolonged pharmacokinetic interaction between capecitabine and a CYP2C9 Substrate, Celecoxib. J Clin Pharmacol. 2019 Dec;59(12):1632–1640.
   PubMed Web of Science ®Google Scholar
• Werner U, Werner D, Rau T, et al. Celecoxib inhibits metabolism of cytochrome P450 2D6 substrate metoprolol in humans. Clin Pharmacol Ther. 2003 Aug;74(2):130–137.
   PubMed Web of Science ®Google Scholar
• Terasawa K. Evidence-based reconstruction of kampo medicine: Part II-the concept of sho. Evid Based Complement Alternat Med. 2004 Sep 1;1(2):119–123.
   PubMed Web of Science ®Google Scholar
• Nakano T, Nishigami C, Irie K, et al. Goreisan prevents brain edema after cerebral ischemic stroke by inhibiting aquaporin 4 upregulation in mice. J Stroke Cerebrovasc Dis. 2018 Mar;27(3):758–763.
   PubMed Web of Science ®Google Scholar
• Yasunaga H. Effect of japanese herbal kampo medicine goreisan on reoperation rates after burr-hole surgery for chronic subdural hematoma: Analysis of a national inpatient database. Evid Based Complement Alternat Med. 2015;2015:817616.
   PubMedGoogle Scholar
• Goto S, Kato K, Yamamoto T, et al. Effectiveness of Goreisan in Preventing Recurrence of Chronic Subdural Hematoma. Asian J Neurosurg. 2018 Apr;13(2):370–374.
   PubMedGoogle Scholar
• Cho KH, Kwon S, Jung WS, et al. Herbal medicine, oreongsan for recurrent chronic subdural hematoma: A case report. Explore (NY). 2017 Mar/Apr;13(2):139–141.
   PubMedGoogle Scholar
• Katayama K, Matsuda N, Kakuta K, et al. The effect of goreisan on the prevention of chronic subdural hematoma recurrence: multi-center randomized controlled study. J Neurotrauma. 2018 Jul 1;35(13):1537–1542.
   PubMed Web of Science ®Google Scholar
• Rabinstein AA, Chung SY, Rudzinski LA, et al. Seizures after evacuation of subdural hematomas: incidence, risk factors, and functional impact. J Neurosurg. 2010 Feb;112(2):455–460.
   PubMed Web of Science ®Google Scholar
• Won SY, Konczalla J, Dubinski D, et al. A systematic review of epileptic seizures in adults with subdural haematomas. Seizure. 2017;45:28–35.
   PubMed Web of Science ®Google Scholar
• Wang HC, Chang WN, Chang HW, et al. Factors predictive of outcome in posttraumatic seizures. J Trauma. 2008 Apr;64(4):883–888.
   PubMedGoogle Scholar
• van Breemen MS, Wilms EB, Vecht CJ. Epilepsy in patients with brain tumours: epidemiology, mechanisms, and management. Lancet Neurol. 2007 May;6(5):421–430.
   PubMed Web of Science ®Google Scholar
• Sabo RA, Hanigan WC, Aldag JC. Chronic subdural hematomas and seizures: the role of prophylactic anticonvulsive medication. Surg Neurol. 1995 Jun;43(6):579–582.
   PubMedGoogle Scholar
• Grobelny BT, Ducruet AF, Zacharia BE, et al. Preoperative antiepileptic drug administration and the incidence of postoperative seizures following bur hole-treated chronic subdural hematoma. J Neurosurg. 2009 Dec;111(6):1257–1262.
   PubMed Web of Science ®Google Scholar
• Ohno K, Maehara T, Ichimura K, et al. Low incidence of seizures in patients with chronic subdural haematoma. J Neurol Neurosurg Psychiatry. 1993 Nov;56(11):1231–1233.
   PubMed Web of Science ®Google Scholar
• Rubin G, Rappaport ZH. Epilepsy in chronic subdural haematoma. Acta Neurochir (Wien). 1993;123(1–2):39–42.
   PubMed Web of Science ®Google Scholar
• Battaglia F, Plas B, Melot A, et al. Is there any benefit from short-term perioperative antiepileptic prophylaxis in patients with chronic subdural haematoma? A retrospective controlled study. Neurochirurgie. 2015 Oct;61(5):324–328.
   PubMed Web of Science ®Google Scholar
• Lavergne P, Labidi M, Brunet MC, et al. Efficacy of antiseizure prophylaxis in chronic subdural hematoma: a cohort study on routinely collected health data. J Neurosurg. 2019;18:1–5.
   Google Scholar
• Lee YK, Ah YM, Choi YJ, et al. Antiepileptic drug adherence and persistence in children with epilepsy attending a large tertiary care children’s hospital. Epileptic Disord. 2016 Dec 1;18(4):408–417.
   PubMed Web of Science ®Google Scholar
• Wirrell EC, Vanderwiel AJ, Nickels L, et al. Impact of Prior Authorization of Antiepileptic Drugs in Children With Epilepsy. Pediatr Neurol. 2018 Jun;83:38–41.
   PubMed Web of Science ®Google Scholar
• Murugupillai R, Ranganathan SS, Wanigasinghe J, et al. Development of outcome criteria to measure effectiveness of antiepileptic therapy in children. Epilepsy Behav. 2018 Mar;80:56–60.
   PubMed Web of Science ®Google Scholar
• Bruun E, Virta LJ, Kalviainen R, et al. Co-morbidity and clinically significant interactions between antiepileptic drugs and other drugs in elderly patients with newly diagnosed epilepsy. Epilepsy Behav. 2017 Aug;73:71–76.
   PubMed Web of Science ®Google Scholar
• Yoon HW, Giraldo EA, Wijdicks EF. Valproic acid and warfarin: an underrecognized drug interaction. Neurocrit Care. 2011 Aug;15(1):182–185.
   PubMed Web of Science ®Google Scholar
• Stollberger C, Finsterer J. Interactions between non-vitamin K oral anticoagulants and antiepileptic drugs. Epilepsy Res. 2016 Oct;126:98–101.
   PubMed Web of Science ®Google Scholar
• Broderick JP, Brott TG, Tomsick T, et al. Ultra-early evaluation of intracerebral hemorrhage. J Neurosurg. 1990 Feb;72(2):195–199.
   PubMed Web of Science ®Google Scholar
• Kwak R, Kadoya S, Suzuki T. Factors affecting the prognosis in thalamic hemorrhage. Stroke. 1983 Jul;14(4):493–500.
   PubMed Web of Science ®Google Scholar
• Petersen OF, Espersen JO. Extradural hematomas: measurement of size by volume summation on CT scanning. Neuroradiology. 1984;26(5):363–367.
   PubMed Web of Science ®Google Scholar
• Tada A, Hisada K, Suzuki T, et al. [Measurement volume of intracranial hematoma by computed tomography (author’s transl)]. No Shinkei Geka. 1981;9(3):251–256.
   PubMedGoogle Scholar
• Zhao KJ, Zhang RY, Sun QF, et al. Comparisons of 2/3Sh estimation technique to computer-assisted planimetric analysis in epidural, subdural and intracerebral hematomas. Neurol Res. 2010 Nov;32(9):910–917.
   PubMed Web of Science ®Google Scholar
• Shi J, Ji HW, Ren FC, et al. Protective effects of tranexamic acid on clopidogrel before coronary artery bypass grafting a multicenter randomized trial. Jama Surg. 2013 Jun;148(6):538–547.
   PubMed Web of Science ®Google Scholar
• Coxibs + oral anticoagulants: risk of interaction. Prescrire Int. 2002 Jun;11(59):85–86.
   PubMedGoogle Scholar
• Taguchi Y, Takashima S, Tanaka K. [A case of phenytoin intoxication caused by interaction between phenytoin and capecitabine]. Brain Nerve. 2015 Feb;67(2):213–217.
   PubMedGoogle Scholar
• Haslemo T, Olsen K, Lunde H, et al. Valproic Acid significantly lowers serum concentrations of olanzapine-an interaction effect comparable with smoking. Ther Drug Monit. 2012 Oct;34(5):512–517.
   PubMed Web of Science ®Google Scholar