82
Views
0
CrossRef citations to date
0
Altmetric
Special Report

Can we manage gut microbiome imbalances in patients with bipolar disorder with pharmacotherapy?

&
Pages 1957-1961 | Received 01 Sep 2023, Accepted 22 Nov 2023, Published online: 11 Dec 2023

References

  • Howland M, Sehamy AE. What are bipolar disorders? Psychiatry. Org - What Are Bipolar Disorders? Ameri Psychi Associ. 2021. [cited Aug 8, 2023]. https://www.psychiatry.org/patients-families/bipolar-disorders/what-are-bipolar-disorders
  • Forte A, Baldessarini RJ, Tondo L, et al. Long-term morbidity in bipolar-I, bipolar-II, and unipolar major depressive disorders. J Affect Disord. 2015;178:71–78. doi: 10.1016/j.jad.2015.02.011
  • Judd LL, Akiskal HS, Schettler PJ, et al. The long-term natural history of the weekly symptomatic status of bipolar I disorder. Arch Gen Psychiatry. 2002;59(6):530–537. doi: 10.1001/archpsyc.59.6.530
  • Shah N, Grover S, Rao GP. Clinical practice guidelines for management of bipolar disorder. Indian J Psychiatry. 2017;59(Suppl 5):S51–S66. doi: 10.4103/0019-5545.196974
  • Rosenblat JD. Chapter 35- Novel therapeutic drug targets for bipolar disorder. In: Quevedo J, Carvalho A, Vieta E, editors. Neurobio Of Bipo Disord. Academic Press; 2021. p. 393–404. doi: 10.1016/B978-0-12-819182-8.00037
  • Kessing LV, Vradi E, Andersen PK. Life expectancy in bipolar disorder. Bipolar Disord. 2015;17(5):543–548. doi: 10.1111/bdi.12296
  • Rosenblat JD, McIntyre RS. Pharmacological approaches to minimizing cardiometabolic side effects of mood stabilizing medications. Curr Treat Options Psychiatry. 2017;4(4):319–332. doi: 10.1007/s40501-017-0131-z
  • Gondalia S, Parkinson L, Stough C, et al. Gut microbiota and bipolar disorder: a review of mechanisms and potential targets for adjunctive therapy. Psychopharmacol (Berl). 2019;236(5):1433–1443. doi: 10.1007/s00213-019-05248-6
  • Evans SJ, Bassis CM, Hein R, et al. The gut microbiome composition associates with bipolar disorder and illness severity. J Psychiatr Res. 2017;87:23–29. doi: 10.1016/j.jpsychires.2016.12.007
  • Flowers SA, Ward KM, Clark CT. The gut microbiome in bipolar disorder and pharmacotherapy management. Neuropsychobiology. 2020;79(1):43–49. doi: 10.1159/000504496
  • Lam KN, Alexander M, Turnbaugh PJ. Precision medicine goes microscopic: engineering the microbiome to Improve drug outcomes. Cell Host Microbe. 2019;26(1):22–34. doi: 10.1016/j.chom.2019.06.011
  • Li Q, Xiaoyan H, Yixin L, et al. Longitudinal Gut Microbiota Dysbiosis Underlies Olanzapine-Induced Weight Gain. Microbiol Spectr. 2023;11(4):e00058–23. doi: 10.1128/spectrum.00058-23
  • Liu BN, Liu XT, Liang ZH, et al. Gut microbiota in obesity. World J Gastroenterol. 2021;27(25):3837–3850. doi: 10.3748/wjg.v27.i25.3837
  • Hu S, Li A, Huang T, et al. Gut microbiota changes in patients with bipolar depression. Adv Sci (Weinheim, Baden-Wurttemberg, Ger. 2019;6(14):1900752. doi: 10.1002/advs.201900752
  • Lu Q, Lai J, Lu H, et al. Gut microbiota in bipolar depression and its relationship to brain function: an advanced exploration. Front Psychiatry. 2019;10:10. https://www.frontiersin.org/articles/10.3389/fpsyt.2019.00784
  • Agarwal K, Manza P, Chapman M, et al. Inflammatory markers in substance use and mood disorders: a neuroimaging perspective. Front Psychiatry. 2022;13:863734. doi: 10.3389/fpsyt.2022.863734
  • ElRakaiby M, Dutilh BE, Rizkallah MR, et al. Pharmacomicrobiomics: the impact of human microbiome variations on systems pharmacology and personalized therapeutics. OMICS. 2014;18(7):402–414. doi: 10.1089/omi.2014.0018
  • Cheng KW, Tseng CH, Tzeng CC, et al. Pharmacological inhibition of bacterial β-glucuronidase prevents irinotecan-induced diarrhea without impairing its antitumor efficacy in vivo. Pharmacol Res. 2019;139:41–49. doi: 10.1016/j.phrs.2018.10.029
  • Forsythe P, Sudo N, Dinan T, et al. Mood and gut feelings. Brain Behav Immun. 2010;24(1):9–16. doi: 10.1016/j.bbi.2009.05.058
  • Collins SM. A role for the gut microbiota in IBS. Nat Rev Gastroenterol Hepatol. 2014;11(8):497–505. doi: 10.1038/nrgastro.2014.40
  • Kers JG, Saccenti E. The power of microbiome studies: some considerations on which alpha and beta metrics to use and how to report results. Front Microbiol. 2022;12:12. https://www.frontiersin.org/articles/10.3389/fmicb.2021.796025
  • Houser MC, Tansey MG. The gut-brain axis: is intestinal inflammation a silent driver of Parkinson’s disease pathogenesis? Npj Park Dis. 2017;3(1):3. doi: 10.1038/s41531-016-0002-0
  • den Besten G, van Eunen K, Groen AK, et al. The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism. J Lipid Res. 2013;54(9):2325–2340. doi: 10.1194/jlr.R036012
  • Tolhurst G, Heffron H, Lam YS, et al. Short-chain fatty acids stimulate glucagon-like peptide-1 secretion via the G-Protein–coupled receptor FFAR2. Diabetes. 1 Feb 2012;61(2):364–371. doi: 10.2337/db11-1019
  • Mayer EA, Tillisch K, Gupta A. Gut/Brain axis and the microbiota. J Clin Invest. 2015;125(3):926–938. doi: 10.1172/JCI76304
  • Dash S, Clarke G, Berk M, et al. The gut microbiome and diet in psychiatry: focus on depression. Curr Opin Psychiatry. 2015;28(1):1–6. doi: 10.1097/YCO.0000000000000117
  • Borkent J, Joannou M, Laman JD, et al. Role of the gut microbiome in three major psychiatric disorders. Psychol Med. 2022;52(7):1222–1242. doi: 10.1017/S0033291722000897
  • Gill SR, Pop M, DeBoy RT, et al. Metagenomic analysis of the human distal gut microbiome. Science. 2006;312(5778):1355–1359. 80-. doi: 10.1126/science.1124234
  • Painold A, Morkl S, Halwachs B, et al. A step ahead: exploring the gut microbiota in inpatients with bipolar disorder during a depressive episode. Bipolar Disord. 2019;21(1):40–49. doi: 10.1111/bdi.12682
  • Lopez-Siles M, Duncan SH, Garcia-Gil LJ, et al. Faecalibacterium prausnitzii: from microbiology to diagnostics and prognostics. Isme J. 2017;11(4):841–852. doi: 10.1038/ismej.2016.176
  • Coello K, Hansen TH, Sorensen N, et al. Gut microbiota composition in patients with newly diagnosed bipolar disorder and their unaffected first-degree relatives. Brain Behav Immun. 2019;75:112–118. doi: 10.1016/j.bbi.2018.09.026
  • Zheng P, Yang J, Li Y, et al. Gut Microbial Signatures Can Discriminate Unipolar from Bipolar Depression. Adv Sci (Weinheim, Baden-Wurttemberg, Ger. 2020;7(7):1902862. doi: 10.1002/advs.201902862
  • Maier L, Pruteanu M, Kuhn, et al. Extensive impact of non-antibiotic drugs on human gut bacteria. Nature. 2018;555(7698):623–628. doi: 10.1038/nature25979
  • Flowers SA, Evans SJ, Ward KM, et al. Interaction between atypical antipsychotics and the gut microbiome in a bipolar disease cohort. Pharmacotherapy. 2017;37(3):261–267. doi: 10.1002/phar.1890
  • Manokaran RK, Gulati S. Gut–brain axis: role of probiotics in neurodevelopmental disorders including autism spectrum disorder. In Probiotics in the prevention and management of human diseases. Academic Press; 2022. p. 353–362. doi: 10.1016/b978-0-12-823733-5.00017-9.
  • Giri S, Mangalam A. The gut microbiome and metabolome in multiple sclerosis. In Microbiome and Metabolome in Diagnosis, therapy, and other strategic applications. Academic Press; 2019. p. 333–340. doi: 10.1016/b978-0-12-815249-2.00034-8.
  • Cussotto S, Strain CR, Fouhy F, et al. Differential effects of psychotropic drugs on microbiome composition and gastrointestinal function. Psychopharmacol (Berl). 2019;236(5):1671–1685. doi: 10.1007/s00213-018-5006-5
  • Bahr SM, Tyler BC, Wooldridge N, et al. Use of the second-generation antipsychotic, risperidone, and secondary weight gain are associated with an altered gut microbiota in children. Transl Psychiatry. 2015;5(10):e652–e652. doi: 10.1038/tp.2015.135
  • Flowers SA, Baxter NT, Ward KM, et al. Effects of atypical antipsychotic treatment and resistant starch supplementation on gut microbiome composition in a cohort of patients with bipolar disorder or schizophrenia. Pharmacotherapy. 2019;39(2):161–170. doi: 10.1002/phar.2214
  • Minichino A, Preston T, Fanshawe JB, et al. Psycho-pharmacomicrobiomics: a systematic review and meta-analysis. Biol Psychiatry. Published online Aug 2023. doi: 10.1016/j.biopsych.2023.07.019
  • Bioque M, Gonzalez-Rodriguez A, Garcia-Rizo C, et al. Targeting the microbiome-gut-brain axis for improving cognition in schizophrenia and major mood disorders: a narrative review. Prog Neuro Psychopharmacol Biol Psychiatry. 2021;105(110130):110130. doi: 10.1016/j.pnpbp.2020.110130
  • Steenbergen L, Sellaro R, van Hemert S, et al. A randomized controlled trial to test the effect of multispecies probiotics on cognitive reactivity to sad mood. Brain Behav Immun. 2015;48:258–264. doi: 10.1016/j.bbi.2015.04.003
  • Dickerson F, Adamos M, Katsafanas E, et al. Adjunctive probiotic microorganisms to prevent rehospitalisation in patients with acute mania: a randomized controlled trial. Bipolar Disord. 2018;20(7):614–621. doi: 10.1111/bdi.12652
  • Sabouri S, Esmailzadeh M, Sadeghinejad, et al. The effect of adjunctive probiotics on markers of inflammation and oxidative stress in bipolar disorder: a Double-blind, randomized, controlled trial. J Psychiatr Pract. 2022;28(5):373–382. doi: 10.1097/PRA.0000000000000660
  • Zeng C, Qiu Y, Li S, et al. Effect of probiotic supplements on oxidative stress biomarkers in first-episode bipolar disorder patients: a randomized, placebo-controlled trial. Front Pharmacol. 2022;13(829815). doi: 10.3389/fphar.2022.829815
  • Kelly JR, Borre Y, O’ Brien C, et al. Transferring the blues: depression-associated gut microbiota induces neurobehavioural changes in the rat. J Psychiatr Res. 2016;82:109–118. doi: 10.1016/j.jpsychires.2016.07.019
  • Zheng P, Zeng B, Zhou C, et al. Gut microbiome remodeling induces depressive-like behaviors through a pathway mediated by the host’s metabolism. Mol Psychiatry. 2016;21(6):786–796. doi: 10.1038/mp.2016.44
  • Chinna Meyyappan A, Forth E, Wallace CJK, et al. Effect of fecal microbiota transplant on symptoms of psychiatric disorders: a systematic review. BMC Psychiatry. 2020;20(1):219–299. doi: 10.1186/s12888-020-02654-5
  • Leclercq S, Le Roy T, Furgiuele S, et al. Gut microbiota-induced changes in β-Hydroxybutyrate metabolism are linked to altered sociability and depression in alcohol use disorder. Cell Rep. 2020;33(2):108238. doi: 10.1016/j.celrep.2020.108238
  • Cooke NCA, Bala A, Allard JP, et al. The safety and efficacy of fecal microbiota transplantation in a population with bipolar disorder during depressive episodes: study protocol for a pilot randomized controlled trial. Pilot Feasibility Stud. 2021;7(1):142. doi: 10.1186/s40814-021-00882-4
  • McGuinness AJ, Davis JA, Dawson SL, et al. A systematic review of gut microbiota composition in observational studies of major depressive disorder, bipolar disorder and schizophrenia. Mol Psychiatry. 2022;27(4):1920–1935. doi: 10.1038/s41380-022-01456-3

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.