119
Views
4
CrossRef citations to date
0
Altmetric
Case Report

Compulsive gabapentin abuse despite lack of desirable effects: A case report

, &
Pages 661-663 | Received 11 Nov 2016, Accepted 01 Dec 2016, Published online: 31 Jan 2017

References

  • American Psychiatric Association. (2013). Diagnostic and Statistical Manual of Mental Disorders (5th ed.). Arlington, VA: American Psychiatric Publishing.
  • Cai, K., Nanga, R. P., Lamprou, L., Schinstine, C., Elliott, M., Hariharan, H., & Epperson, C. N. (2012). The impact of gabapentin administration on brain GABA and glutamate concentrations: A 7T 1H-MRS study. Neuropsychopharmacology, 37(13), 2764–2771. doi: 10.1038/npp.2012.142
  • Cunningham, M. O., Woodhall, G. L., Thompson, S. E., Dooley, D. J., & Jones, R. S. (2004). Dual effects of gabapentin and pregabalin on glutamate release at rat entorhinal synapses in vitro. European Journal of Neuroscience, 20(6), 1566–1576. doi: 10.1111/j.1460-9568.2004.03625.x
  • Del Paggio, D. (2005). Psychotropic medication abuse in correctional facilities. Bay Area Psychopharmacology Newsletter, 8(2), 1, 5. Available at: http://bhcs.co.alameda.ca.us/
  • Howland, R. H. (2013). Gabapentin for the treatment of substance use disorders. Journal of Psychosocial Nursing and Mental Health Services, 51(12), 11–14. doi: 10.3928/02793695-20131120-01
  • Kapil, V., Green, J. L., Le Lait, M. C., Wood, D. M., & Dargan, P. I. (2014). Misuse of the γ-aminobutyric acid analogues baclofen, gabapentin and pregabalin in the UK. British Journal of Clinical Pharmacology, 78(1), 190–191. doi: 10.1111/bcp.12277
  • Mack, A. (2003). Examination of the evidence for off-label use of gabapentin. Journal of Managed Care Pharmacy, 9(6), 559–568. doi: 10.18553/jmcp.2003.9.6.559
  • Mah, L., & Hart, M. (2013). Gabapentin withdrawal: Case report in an older adult and review of the literature. Journal of the American Geriatrics Society, 61(9), 1635–1637. doi: 10.1111/jgs.12427
  • Manji, H. K., Quiroz, J. A., Payne, J. L., et al. (2003). The underlying neurobiology of bipolar disorder. World Psychiatry, 2(3), 136–146.
  • Mason, B. J., Quello, S., Goodell, V., Shadan, F., Kyle, M., & Begovic, A. (2014). Gabapentin treatment for alcohol dependence: A randomized clinical trial. JAMA Internal Medicine, 174(1), 70–77. doi: 10.1001/jamainternmed.2013.11950
  • Pittenger, C., Bloch, M. H., & Williams, K. (2011). Glutamate abnormalities in obsessive compulsive disorder: Neurobiology, pathophysiology, and treatment. Pharmacology & Therapeutics, 132(3), 314–332. doi: 10.1016/j.pharmthera.2011.09.006
  • Pittenger, C., & Desan, P. H. (2007). Gabapentin abuse, and delirium tremens upon gabapentin withdrawal. Journal of Clinical Psychiatry, 68(3), 483–484. doi:10.4088/jcp.v68n0320a
  • Reccoppa, L., Malcolm, R., & Ware, M. (2004). Gabapentin abuse in inmates with prior history of cocaine dependence. The American Journal on Addictions, 13(3), 321–323. doi: 10.1080/10550490490460300
  • Rosebush, P. I., MacQueen, G. M., & Mazurek, M. F. (1999). Catatonia following gabapentin withdrawal. Journal of Clinical Psychopharmacology, 19(2), 188–189. doi:10.1097/00004714-199904000-00019
  • See, S., Hendriks, E., & Hsiung, L. (2011). Akathisia induced by gabapentin withdrawal. Annals of Pharmacotherapy, 45(6), e31–e31. doi:10.1345/aph.1q057
  • Sills, G. J. (2006). The mechanisms of action of gabapentin and pregabalin. Current Opinion in Pharmacology, 6(1), 108–113. doi:10.1016/j.coph.2005.11.003
  • Smith, B. H., Higgins, C., Baldacchino, A., Kidd, B., & Bannister, J. (2012). Substance misuse of gabapentin. British Journal of General Practice, 62(601), 406–407. doi:10.3399/bjgp12x653516
  • Suto, T., Severino, A. L., Eisenach, J. C., & Hayashida, K. (2014). Gabapentin increases extracellular glutamatergic level in the locus coeruleus via astroglial glutamate transporter-dependent mechanisms. Neuropharmacology, 81, 95–100. doi:10.1016/j.neuropharm.2014.01.040
  • Takasu, K., Ono, H., & Tanabe, M. (2008). Gabapentin produces PKA-dependent pre-synaptic inhibition of GABAergic synaptic transmission in LC neurons following partial nerve injury in mice. Journal of Neurochemistry, 105(3), 933–942. doi:10.1111/j.1471-4159.2008.05212.x
  • Trinka, E., Niedermüller, U., Thaler, C., Doering, S., Moroder, T., Ladurner, G., & Bauer, G. (2000). Gabapentin-induced mood changes with hypomanic features in adults. Seizure, 9(7), 505–508. doi:10.1053/seiz.2000.0445
  • Victorri-Vigneau, C., Guerlais, M., & Jolliet, P. (2007). Abuse, dependency and withdrawal with gabapentin: A first case report. Pharmacopsychiatry, 40(1), 43–44. doi:10.1055/s-2006-958522

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.