205
Views
1
CrossRef citations to date
0
Altmetric
Review Article

Fatal self-poisoning with amitriptyline: a case report and brief review of literature

, , , & ORCID Icon
Pages 489-491 | Received 11 Nov 2021, Accepted 24 Apr 2022, Published online: 26 Apr 2022

References

  • Abeyaratne, D. D., Liyanapathirana, C., Gamage, A., Karunarathne, P., Botheju, M., & Indrakumar, J. (2016). Survival after severe amitriptyline poisoning with prolonged ventricular tachycardia and cardiac arrest. BMC Research Notes, 9(1), 167. https://doi.org/10.1186/s13104-016-1963-0
  • Apple, F. S., & Bandt, C. M. (1988). Liver and blood postmortem tricyclic antidepressant concentrations. American Journal of Clinical Pathology, 89(6), 794–796. https://doi.org/10.1093/ajcp/89.6.794
  • Breyer-Pfaff, U. (2004). The metabolic fate of amitriptyline, nortriptyline and amitriptylinoxide in man. Drug Metabolism Reviews, 36(3–4), 723–746. https://doi.org/10.1081/dmr-200033482
  • Chan, C. Y., & Waring, W. S. (2007). Images in cardiovascular medicine. Tricyclic cardiotoxicity treated with sodium bicarbonate. Circulation, 115(5), e63–4. https://doi.org/10.1161/CIRCULATIONAHA.106.657247
  • Crome, P., & Braithwaite, R. A. (1978). Relationship between clinical features of tricyclic antidepressant poisoning and plasma concentrations in children. Archives of Disease in Childhood, 53(11), 902–905. https://doi.org/10.1136/adc.53.11.902
  • Gillman, P. K. (2007). Tricyclic antidepressant pharmacology and therapeutic drug interactions updated. British Journal of Pharmacology, 151(6), 737–748. https://doi.org/10.1038/sj.bjp.0707253
  • Han, E., Kim, E., Hong, H., Jeong, S., Kim, J., In, S., Chung, H., & Lee, S. (2012). Evaluation of postmortem redistribution phenomena for commonly encountered drugs. Forensic Science International, 219(1–3), 265–271. https://doi.org/10.1016/j.forsciint.2012.01.016
  • Hanzlick, R. (1989). Postmortem tricyclic antidepressant concentrations. Lethal versus nonlethal levels. The American Journal of Forensic Medicine and Pathology, 10(4), 326–329. https://doi.org/10.1097/00000433-198912000-00009
  • Hilberg, T., Mørland, J., & Bjørneboe, A. (1994). Postmortem release of amitriptyline from the lungs; a mechanism of postmortem drug redistribution. Forensic Science International, 64(1), 47–55. https://doi.org/10.1016/0379-0738(94)90241-0
  • Hocaoğlu, N., Murat, N., Mıcılı, S. C., Aydın, B., Ergür, B. U., & Kalkan, Ş. (2016). Correlation between amitriptyline-induced cardiotoxic effects and cardiac s100b protein in isolated rat hearts. Balkan Medical Journal, 33(6), 681–687. https://doi.org/10.5152/balkanmedj.2016.150435
  • Kennedy, M. C. (2010). Post-mortem drug concentrations. Internal Medicine Journal, 40(3), 183–187. https://doi.org/10.1111/j.1445-5994.2009.02111.x
  • Kerr, G. W., Mcguffie, A. C., & Wilkie, S. (2001). Tricyclic antidepressant overdose: A review. Emergency Medicine Journal: EMJ, 18(4), 236–241. https://doi.org/10.1136/emj.18.4.236
  • Köppel, C., Wiegreffe, A., & Tenczer, J. (1992). Clinical course, therapy, outcome and analytical data in amitriptyline and combined amitriptyline/chlordiazepoxide overdose. Human & Experimental Toxicology, 11(6), 458–465. https://doi.org/10.1177/096032719201100604
  • Linder, M. W., & Keck, P. E., Jr. (1998). Standards of laboratory practice: Antidepressant drug monitoring. National Academy of Clinical Biochemistry. Clinical Chemistry, 44(5), 1073–1084. https://www.ncbi.nlm.nih.gov/pubmed/9590392.
  • Nelson, J. C., & Spyker, D. A. (2017). Morbidity and mortality associated with medications used in the treatment of depression: An analysis of cases reported to U.S. poison control centers, 2000-2014. The American Journal of Psychiatry, 174(5), 438–450. https://doi.org/10.1176/appi.ajp.2016.16050523
  • Steel, C. M., O’duffy, J., & Brown, S. S. (1967). Clinical effects and treatment of imipramine and amitriptyline poisoning in children. British Medical Journal, 3(5566), 663–667. https://doi.org/10.1136/bmj.3.5566.663
  • Stiakakis, I., Belivanis, S. D., Tzatzarakis, M. N., Fragoulis, M., & Tsatsakis, A. M. (2009). Disputed case of homicide by smothering due to severe amitriptyline intoxication of the victim. Journal of Forensic and Legal Medicine, 16(5), 280–283. https://doi.org/10.1016/j.jflm.2008.12.001

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.