References
- Duman RS, Aghajanian GK. Synaptic dysfunction in depression: potential therapeutic targets. Science. 2012;338:68–72. PMCID: PMC4424898.
- Wahl-Schott C, Biel M. HCN channels: structure, cellular regulation and physiological function. Cell Mol Life Sci. 2009;66:470–494. PMCID: In process.
- Lewis AS, Vaidya SP, Blaiss CA, et al. Deletion of the hyperpolarization-activated cyclic nucleotide-gated channel auxiliary subunit TRIP8b impairs hippocampal Ih localization and function and promotes antidepressant behavior in mice. J Neurosci. 2011;31:7424–7440. PMCID: PMC3169171.
- Kim CS, Chang PY, Johnston D. Enhancement of dorsal hippocampal activity by knockdown of HCN1 channels leads to anxiolytic- and antidepressant-like behaviors. Neuron. 2012;75:503–516. PMCID: PMC3418514.
- Cryan JF, Mombereau C, Vassout A. The tail suspension test as a model for assessing antidepressant activity: review of pharmacological and genetic studies in mice. Neurosci Biobehav Rev. 2005;29:571–625. PMCID: In process.
- Han Y, Lyman K, Clutter M, et al. Identification of small-molecule inhibitors of hyperpolarization-activated cyclic nucleotide–gated channels. J Biomol Screen. 2015;20:1124–1131. PMCID: PMC4755285.
- Heuermann RJ, Jaramillo TC, Ying S-W, et al. Reduction of thalamic and cortical Ih by deletion of TRIP8b produces a mouse model of human absence epilepsy. Neurobiol Dis. 2016;85:81–92. PMCID: PMC4688217.
- Han Y, Heuermann RJ, Lyman KA, et al. HCN-channel dendritic targeting requires bipartite interaction with TRIP8b and regulates antidepressant-like behavioral effects. Mol Psychiatry. 2016. PMCID: In process.
- Bankston JR, Camp SS, DiMaio F, et al. Structure and stoichiometry of an accessory subunit TRIP8b interaction with hyperpolarization-activated cyclic nucleotide-gated channels. Proc Natl Acad Sci USA. 2012;109:7899–7904. PMCID: PMC3356637.
- Santoro B, Hu L, Liu H, et al. TRIP8b regulates HCN1 channel trafficking and gating through two distinct C-terminal interaction sites. J Neurosci. 2011;31:4074–4086. PMCID: PMC3077297.
- Piskorowski R, Santoro B, Siegelbaum SA. TRIP8b splice forms act in concert to regulate the localization and expression of HCN1 channels in CA1 pyramidal neurons. Neuron. 2011;70:495–509. PMCID: PMC3107038.
- Brocard C, Hartig A. Peroxisome targeting signal 1: is it really a simple tripeptide? Biochim Biophys Acta. 2006;12:1565–1573. PMCID: In process.
- Gatto GJ Jr., Geisbrecht BV, Gould SJ, et al. Peroxisomal targeting signal-1 recognition by the TPR domains of human PEX5. Nat Struct Biol. 2000;12:1091–1095.
- Saponaro A, Pauleta SR, Cantini F, et al. Structural basis for the mutual antagonism of cAMP and TRIP8b in regulating HCN channel function. Proc Natl Acad Sci USA. 2014;40:14577–14582. PMCID: PMC4210022.
- Friedman AK, Walsh JJ, Juarez B, et al. Enhancing depression mechanisms in midbrain dopamine neurons achieves homeostatic resilience. Science. 2014;344:313–319. PMCID: PMC4334447.