238
Views
2
CrossRef citations to date
0
Altmetric
Original research

Clinical profile of acute pancreatitis following treatment with protease inhibitors: a real-world analysis of post-marketing surveillance data

, , & ORCID Icon
Pages 1109-1115 | Received 25 Jan 2021, Accepted 20 May 2021, Published online: 01 Jun 2021

References

  • Crum NF, Riffenburgh RH, Wegner S, et al. Comparisons of causes of death and mortality rates among HIV-infected persons. I Acquir Immune Defic Syndr. 2006;41(2):194–200.
  • De Leuw P, Stephan C. Protease inhibitor therapy for hepatitis C virus-infection. Expert Opin Pharmacother. 2018 Apr;19(6):577–587.
  • Ghosh AK, Osswald HL, Prato G. Recent progress in the development of HIV-1 protease inhibitors for the treatment of HIV/AIDS. J Med Chem. 2016 Jun 9;59(11):5172–5208.
  • Hughes PJ, Cretton-Scott E, Teague A, et al. Protease inhibitors for patients with HIV-1 infection: a comparative overview. P T. 2011 Jun;36(6):332–345.
  • Palella FJ Jr., Delaney KM, Moorman AC, et al. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV outpatient study investigators. N Engl J Med. 1998 Mar 26;338(13):853–860.
  • Carnovale C, Pozzi M, Dassano A, et al. The impact of a successful treatment of hepatitis C virus on glyco-metabolic control in diabetic patients: a systematic review and meta-analysis. Acta Diabetol. 2019 Mar;56(3):341–354.
  • Chu CM, Cheng VC, Hung IF, et al. Role of lopinavir/ritonavir in the treatment of SARS: initial virological and clinical findings. Thorax. 2004 Mar;59(3):252–256.
  • Sheahan TP, Sims AC, Leist SR, et al. Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV. Nat Commun. 2020 Jan 10;11(1):222.
  • Kim UJ, Won EJ, Kee SJ, et al. Combination therapy with lopinavir/ritonavir, ribavirin and interferon-alpha for middle east respiratory syndrome. Antivir Ther. 2016;21(5):455–459.
  • Solerte SB, D’Addio F, Trevisan R, et al. Sitagliptin treatment at the time of hospitalization was associated with reduced mortality in patients with type 2 diabetes and COVID-19: a multicenter, case-control, retrospective, observational study. Diabetes Care. 2020 Dec;43(12):2999–3006.
  • Walmsley S. Protease inhibitor-based regimens for HIV therapy: safety and efficacy. JAIDS J Acquir Immune Defic Syndr. 2007 Jun 1;45(Suppl 1):SS5–31.
  • Liu J, Shah SK, Basu-Ray I, et al. QT prolongation in HIV-positive patients: review article. Indian Heart J. 2019 Nov-Dec;71(6):434–439.
  • Calza L, Manfredi R, Farneti B, et al. Incidence of hyperlipidaemia in a cohort of 212 HIV-infected patients receiving a protease inhibitor-based antiretroviral therapy. Int J Antimicrob Agents. 2003 Jul;22(1):54–59.
  • Warriner AH, Burkholder GA, Overton ET. HIV-related metabolic comorbidities in the current ART era. Infect Dis Clin North Am. 2014 Sep;28(3):457–476.
  • Montessori V, Press N, Harris M, et al. Adverse effects of antiretroviral therapy for HIV infection. CMAJ : Canadian Med Assoc J = Journal De l’Association Medicale Canadienne. 2004 Jan 20;170(2):229–238.
  • Safrin S, Grunfeld C. Fat distribution and metabolic changes in patients with HIV infection. AIDS. 1999 Dec 24;13(18):2493–2505.
  • Oliveira NM, Ferreira FA, Yonamine RY, et al. Antiretroviral drugs and acute pancreatitis in HIV/AIDS patients: is there any association? A literature review. Einstein (Sao Paulo). 2014 Jan-Mar;12(1):112–119.
  • Croxtall JD, Perry CM. Lopinavir/Ritonavir: a review of its use in the management of HIV-1 infection. Drugs. 2010 Oct 1;70(14):1885–1915.
  • Reisler RB, Murphy RL, Redfield RR, et al. Incidence of pancreatitis in HIV-1-infected individuals enrolled in 20 adult AIDS clinical trials group studies: lessons learned. J Acquir Immune Defic Syndr. 2005 Jun 1;39(2):159–166.
  • Bush ZM, Kosmiski LA. Acute pancreatitis in HIV-infected patients: are etiologies changing since the introduction of protease inhibitor therapy? Pancreas. 2003 Jul;27(1):e1–5.
  • Manfredi R, Calza L, Chiodo F. A case-control study of HIV-associated pancreatic abnormalities during HAART era. Focus on emerging risk factors and specific management. Eur J Med Res. 2004 Dec 22; 9(12):537–544.
  • Manfredi R, Calza L. HIV infection and the pancreas: risk factors and potential management guidelines. Int J STD AIDS. 2008 Feb;19(2):99–105.
  • Mirete G, Masia M, Gutierrez F, et al. Acute pancreatitis as a complication of ritonavir therapy in a patient with AIDS. Eur J Clin Microbiol Infect Dis. 1998 Nov;17(11):810–811.
  • Perry RC, Cushing HE, Deeg MA, et al. Ritonavir, triglycerides, and pancreatitis. Clin Infect Dis. 1999 Jan;28(1):161–162.
  • Di Martino V, Ezenfis J, Benhamou Y, et al. Severe acute pancreatitis related to the use of nelfinavir in HIV infection: report of a case with positive rechallenge. AIDS. 1999 Jul 30;13(11):1421–1423.
  • Van Puijenbroek EP, Bate A, Leufkens HG, et al. A comparison of measures of disproportionality for signal detection in spontaneous reporting systems for adverse drug reactions. Pharmacoepidemiol Drug Saf. 2002 Jan-Feb;11(1):3–10.
  • Szumilas M. Explaining odds ratios. J Canadian Acad Child Adolescent Psych = J de l’Academie canadienne de psychiatrie de l’enfant et de l’adolescent 2010 Aug;19(3):227–229.
  • Ooba N, Kubota K. Selected control events and reporting odds ratio in signal detection methodology. Pharmacoepidemiol Drug Saf. 2010 Nov;19(11):1159–1165.
  • Evans SJ, Waller PC, Davis S. Use of proportional reporting ratios (PRRs) for signal generation from spontaneous adverse drug reaction reports. Pharmacoepidemiol Drug Saf. 2001 Oct-Nov;10(6):483–486.
  • Hauben M, Madigan D, Gerrits CM, et al. The role of data mining in pharmacovigilance. Expert Opin Drug Saf. 2005 Sep;4(5):929–948.
  • Norén GN, Bate A, Orre R, et al. Extending the methods used to screen the WHO drug safety database towards analysis of complex associations and improved accuracy for rare events. Stat Med. 2006 Nov 15;25(21):3740–3757.
  • Hauben M. A brief primer on automated signal detection. Ann Pharmacother. 2003 Jul-Aug;37(7–8):1117–1123.
  • Louis TA, Shen W. [Bayesian data mining in large frequency tables, with an application to the fda spontaneous reporting system]: discussion. Am Stat. 1999;53(3):196.
  • Szarfman A, Machado SG, O’Neill RT. Use of screening algorithms and computer systems to efficiently signal higher-than-expected combinations of drugs and events in the US FDA’s spontaneous reports database. Drug Saf. 2002;25(6):381–392.
  • Moore RD, Keruly JC, Chaisson RE. Incidence of pancreatitis in HIV-infected patients receiving nucleoside reverse transcriptase inhibitor drugs. AIDS. 2001 Mar 30;15(5):617–620.
  • Dragovic G, Milic N, Jevtovic DJ. Incidence of acute pancreatitis and nucleoside reverse transcriptase inhibitors usage. Int J STD AIDS. 2005 Jun;16(6):427–429.
  • Johnson AS, Song R, Hall HI. Estimated HIV incidence, prevalence, and undiagnosed infections in US States and Washington, DC, 2010–2014. J Acquired Immune Deficiency Syndromes. 1999;2017:116.
  • Guo JJ, Jang R, Louder A, et al. Acute pancreatitis associated with different combination therapies in patients infected with human immunodeficiency virus. Pharmacotherapy. 2005 Aug;25(8):1044–1054.
  • Riedel DJ, Gebo KA, Moore RD, et al. A ten-year analysis of the incidence and risk factors for acute pancreatitis requiring hospitalization in an urban HIV clinical cohort. AIDS Patient Care STDS. 2008 Feb;22(2):113–121.
  • Friedewald VE, Ballantyne CM, Bays HE, et al. The editor’s roundtable: hypertriglyceridemia. Am J Cardiol. 2013 Oct 15;112(8):1133–1141.
  • Lederle FA, Bloomfield HE. Drug treatment of asymptomatic hypertriglyceridemia to prevent pancreatitis: where is the evidence? Ann Intern Med. 2012 Nov 6;157(9):662–664.
  • Sun HY, Chang SY, Sheng WH, et al. Incidence of acute pancreatitis in human immunodeficiency virus-positive patients with hypertriglyceridemia: is it really high? Pancreas. 2012 Mar;41(2):283–289.
  • Marot JC, Jonckheere S, Munyentwali H, et al. Tigecycline-induced acute pancreatitis: about two cases and review of the literature. Acta Clin Belg. 2012 May-Jun;67(3):229–232.
  • Tsiodras S, Mantzoros C, Hammer S, et al. Effects of protease inhibitors on hyperglycemia, hyperlipidemia, and lipodystrophy: a 5-year cohort study. Arch Internal Med. 2000 Jul 10;160(13):2050–2056.
  • Salami AK, Akande AA, Olokoba AB. Serum lipids and glucose abnormalities in HIV/AIDS patients on antiretroviral therapies. West Afr J Med. 2009 Jan;28(1):10–15.
  • Lugassy DM, Farmer BM, Nelson LS. Metabolic and hepatobiliary side effects of antiretroviral therapy (ART). Emerg Med Clin North Am. 2010 May;28(2):409–419.
  • Golomb BA, Verden A, Messner AK, et al. Amyotrophic lateral sclerosis associated with statin use: a disproportionality analysis of the FDA’s adverse event reporting system. Drug saf. 2018 Apr;41(4):403–413.
  • Shen J, Yang J, Zhao B. A survey of the FDA’s adverse event reporting system database concerning urogenital tract infections and sodium glucose cotransporter‐2Inhibitor use. Diabetes Ther. 2019 Jun;10(3):1043–1050.
  • Fan Q, Hu Y, Yang C, et al. Myocarditis following the use of different immune checkpoint inhibitor regimens: a real-world analysis of post-marketing surveillance data. Int Immunopharmacol. 2019;76:105866.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.