References
- Australian Institute of Health and Welfare. Older Australia at a glance. 2018. [cited 2021 Jun 1]. Available from: https://www.aihw.gov.au/reports/older-people/older-australia-at-a-glance/contents/summary
- Australian Bureau of Statistics. Disability, ageing and carers, Australia: summary of findings. 2015. [cited 2021 May 06]. Available from: https://www.abs.gov.au/ausstats/[email protected]/Lookup/4430.0main+features302015.
- U.S. Department of Health and Human Services. profile of older Americans. 2019. [cited 2021 May 06]. Available from: https://acl.gov/sites/default/files/Aging%20and%20Disability%20in%20America/2019ProfileOlderAmericans508.pdf
- Lukin B, Fan L-J, Zhao J-Z, et al. Emergency department use among patients from residential aged care facilities under a hospital in the nursing home scheme in public hospitals in Queensland Australia. World J Emerg Med. 2016;7(3):183–190.
- Dwyer R, Gabbe B, Stoelwinder JU, et al. A systematic review of outcomes following emergency transfer to hospital for residents of aged care facilities. Age Ageing. 2014;43(6):759–766.
- World Health Organization. Topic 11: improving medication safety. 2014. [cited 2021 May 07]. Available from: https://www.who.int/patientsafety/education/curriculum/who_mc_topic-11.pdf
- van Mil JW, Westerlund LO, Hersberger KE, et al. Drug-related problem classification systems. Ann Pharmacother. 2004;38(5):859–867.
- Ackroyd-Stolarz S, Hartnell N, MacKinnon NJ. Demystifying medication safety: making sense of the terminology. Res Social Adm Pharm. 2006;2(2):280–289.
- Gyllensten H, Rehnberg C, Jönsson AK, et al. Cost of illness of patient-reported adverse drug events: a population-based cross-sectional survey. BMJ Open. 2013;3(6):e002574.
- EUROmediCAT. Governance. [cited 2022 Feb 16]. Available from: https://www.euromedicat.eu/currentresearchanddata/governance
- Kollek R, van Aken J, Feuerstein G, et al. Pharmacogenetics, adverse drug reactions and public health. Community Genet. 2006;9(1):50–54.
- Nebeker JR, Barach P, Samore MH. Clarifying adverse drug events: a clinician’s guide to terminology, documentation, and reporting. Ann Intern Med. 2004;140(10):795–801.
- Lazarou J, Pomeranz BH, Corey PN. Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies. JAMA. 1998;279(15):1200–1205.
- Commonwealth of Australia. Drug-related deaths and harm among young people. 2004. [cited 2021 May 10]. Available from: https://www1.health.gov.au/internet/publications/publishing.nsf/Content/drugtreat-pubs-front5-fa-toc~drugtreat-pubs-front5-fa-secb~drugtreat-pubs-front5-fa-secb-4~drugtreat-pubs-front5-fa-secb-4-5
- Ali S, Aboheimed NI, Al-Zaagi IA, et al. Analysis of medication errors at a large tertiary care hospital in Saudi Arabia: a retrospective analysis. Int J Clin Pharm. 2017;39(5):1004–1007.
- Bates DW, Boyle DL, Vliet MBV, et al. Relationship between medication errors and adverse drug events. J Gen Intern Med. 1995;10(4):199–205.
- Bradley MC, Fahey T, Cahir C, et al. Potentially inappropriate prescribing and cost outcomes for older people: a cross-sectional study using the Northern Ireland enhanced prescribing database. Eur J Clin Pharmacol. 2012;68(10):1425–1433.
- Gandhi TK, Weingart SN, Borus J, et al. Adverse drug events in ambulatory care. N Engl J Med. 2003;348(16):1556–1564.
- Garfield S, Barber N, Walley P, et al. Quality of medication use in primary care–mapping the problem, working to a solution: a systematic review of the literature. BMC Med. 2009;7(1):50.
- Handler SM, Hanlon JT. Detecting adverse drug events using a nursing home specific trigger tool. Ann Longterm Care. 2010;18(5):17–22.
- Hohl CM, Small SS, Peddie D, et al. Why clinicians don’t report adverse drug events: qualitative study. JMIR Public Health Surveill. 2018;4(1):e21–e.
- Falconer N, Barras M, Martin J, et al. Defining and classifying terminology for medication harm: a call for consensus. Eur J Clin Pharmacol. 2019;75(2):137–145.
- Ballard C, Corbett A, Orrell M, et al. Impact of person-centred care training and person-centred activities on quality of life, agitation, and antipsychotic use in people with dementia living in nursing homes: a cluster-randomised controlled trial. PLoS Med. 2018;15(2):e1002500.
- Wilson NM, March LM, Sambrook PN, et al. Medication safety in residential aged-care facilities: a perspective. Ther Adv Drug Saf. 2010;1(1):11–20.
- European Medicines Agency. Guideline on good pharmacovigilance practices (GVP). [cited 2022 Feb 15]. Available from: https://www.ema.europa.eu/en/documents/scientific-guideline/guideline-good-pharmacovigilance-practices-annex-i-definitions-rev-4_en.pdf
- World Health Organization. Glossary. [cited 2022 Feb 15]. Available from: https://whopvresources.org/glossary.php
- The National Academic Press. Institute of medicine. Preventing medication errors. Washington (DC). 2007. [cited 2021 Apr 21]. Available from: https://www.nap.edu/catalog/11623/preventing-medication-errors
- Gurwitz JH, Field TS, Avorn J, et al. Incidence and preventability of adverse drug events in nursing homes. Am J Med. 2000;109(2):87–94.
- World Health Organization. Glossary of patient safety concepts and references. 2009. [cited 2021 Apr 26]. Available from: https://www.who.int/patientsafety/taxonomy/icps_technical_annex2.pdf
- Institute of medicine committee on quality of health care in A. In: Kohn LT, Corrigan JM, Donaldson MS, editors. To err is human: building a safer health system. Washington (DC): National Academies Press (US); 2000.
- Leape LL, Brennan TA, Laird N, et al. The nature of adverse events in hospitalized patients. Results of the harvard medical practice study II. N Engl J Med. 1991;324(6):377–384.
- Tam KW, Kwok KH, Fan YM, et al. Detection and prevention of medication misadventures in general practice. Int J Qual Health Care. 2008;20(3):192–199.
- Arfken CL, Wilson JG, Aronson SM. Retrospective review of selective serotonin reuptake inhibitors and falling in older nursing home residents. Int Psychogeriatr. 2001;13(1):85–91.
- Cooper JW, Freeman MH, Cook CL, et al. Assessment of psychotropic and psychoactive drug loads and falls in nursing facility residents. Consult Pharm. 2007;22(6):483–489.
- Al-Jumaili AA, Doucette WR. A systems approach to identify factors influencing adverse drug events in nursing homes. J Am Geriatr Soc. 2018;66(7):1420–1427.
- Field TS, Gurwitz JH, Avorn J, et al. Risk factors for adverse drug events among nursing home residents. Arch Intern Med. 2001;161(13):1629–1634.
- Hien LTT, Cumming RG, Cameron ID, et al. Atypical antipsychotic medications and risk of falls in residents of aged care facilities. J Am Geriatr Soc. 2005;53(8):1290–1295.
- Liperoti R, Sganga F, Landi F, et al. Antipsychotic drug interactions and mortality among nursing home residents with cognitive impairment. J Clin Psychiatry. 2017;78(1):e76–e82.
- Lord SR, March LM, Cameron ID, et al. Differing risk factors for falls in nursing home and intermediate-care residents who can and cannot stand unaided. J Am Geriatr Soc. 2003;51(11):1645–1650.
- Nace DA, Hanlon JT, Crnich CJ, et al. A multifaceted antimicrobial stewardship program for the treatment of uncomplicated cystitis in nursing home residents. JAMA Intern Med. 2020;180(7):944–951.
- Pasay DK, Guirguis MS, Shkrobot RC, et al. Antimicrobial stewardship in rural nursing homes: impact of interprofessional education and clinical decision tool implementation on urinary tract infection treatment in a cluster randomized trial. Infect Control Hosp Epidemiol. 2019;40(4):432–437.
- Hosia-Randell HM, Muurinen SM, Pitkälä KH. Exposure to potentially inappropriate drugs and drug-drug interactions in elderly nursing home residents in Helsinki, Finland: a cross-sectional study. Drugs Aging. 2008;25(8):683–692.
- Liao HL, Chen JT, Ma TC, et al. Analysis of drug-drug interactions (DDIs) in nursing homes in Central Taiwan. Arch Gerontol Geriatr. 2008;47(1):99–107.
- Abbatecola AM, Bo M, Barbagallo M, et al. Severe hypoglycemia is associated with antidiabetic oral treatment compared with insulin analogs in nursing home patients with type 2 diabetes and dementia: results from the DIMORA study. J Am Med Dir Assoc. 2015;16(4):349.e7–12.
- Helvik AS, Šaltytė Benth J, Wu B, et al. Persistent use of psychotropic drugs in nursing home residents in Norway. BMC Geriatr. 2017;17(1):52.
- Nijk RM, Zuidema SU, Koopmans RT. Prevalence and correlates of psychotropic drug use in dutch nursing-home patients with dementia. Int Psychogeriatr. 2009;21(3):485–493.
- Zuidema SU, de Jonghe JF, Verhey FR, et al. Psychotropic drug prescription in nursing home patients with dementia: influence of environmental correlates and staff distress on physicians’ prescription behavior. Int Psychogeriatr. 2011;23(10):1632–1639.
- Alldred DP, Standage C, Zermansky AG, et al. The recording of drug sensitivities for older people living in care homes. Br J Clin Pharmacol. 2010;69(5):553–557.
- Petrillo LA, Gan S, Jing B, et al. Hypoglycemia in hospice patients with type 2 diabetes in a national sample of nursing homes. JAMA Intern Med. 2018;178(5):713–715.
- Travis L, Worth LJ, Trubiano J, et al. Burden of antibiotic allergy labels in Australian aged care residents: findings from a national point-prevalence survey. Infect Control Hosp Epidemiol. 2020;41(6):641–644.
- Handler SM, Cheung PW, Culley CM, et al. Determining the incidence of drug-associated acute kidney injury in nursing home residents. J Am Med Dir Assoc. 2014;15(10):719–724.
- Burato S, Leonardi L, Antonazzo IC, et al. Comparing the prevalence of polypharmacy and potential drug-drug interactions in nursing homes and in the community dwelling elderly of Emilia Romagna Region. Front Pharmacol. 2020;11:624888.
- Jobski K, Hoffmann F, Herget-Rosenthal S, et al. Drug interactions with oral anticoagulants in German nursing home residents: comparison between vitamin K antagonists and non-vitamin K antagonist oral anticoagulants based on two nested case-control studies. Clin Res Cardiol. 2020;109(4):465–475.
- Maust DT, Langa KM, Blow FC, et al. Psychotropic use and associated neuropsychiatric symptoms among patients with dementia in the USA. Int J Geriatr Psychiatry. 2017;32(2):164–174.
- Council for International Organizations of Medical Sciences (CIOMS). Reporting adverse drug reactions. 1999. [cited 2021 May 03]. Available from: https://cioms.ch/wp-content/uploads/2017/01/reporting_adverse_drug.pdf
- Agbabiaka TB, Savović J, Ernst E. Methods for causality assessment of adverse drug reactions: a systematic review. Drug Saf. 2008;31(1):21–37.
- Klopotowska JE, Wierenga PC, Stuijt CC, et al. Adverse drug events in older hospitalized patients: results and reliability of a comprehensive and structured identification strategy. PLoS One. 2013;8(8):e71045.
- Thürmann PA. Methods and systems to detect adverse drug reactions in hospitals. Drug Saf. 2001;24(13):961–968.
- Forster AJ, Jennings A, Chow C, et al. A systematic review to evaluate the accuracy of electronic adverse drug event detection. J Am Med Inform Assoc. 2012;19(1):31–38.
- Díaz-Gutiérrez MJ, Martínez-Cengotitabengoa M, Sáez De Adana E, et al. Relationship between the use of benzodiazepines and falls in older adults: a systematic review. Maturitas. 2017;101:17–22.
- American Geriatrics Society. Updated AGS beers criteria(R) for potentially inappropriate medication use in older adults. J Am Geriatr Soc. 2019;67(4):674–694. 2019.
- Tabak YP, Srinivasan A, Yu KC, et al. Hospital-level high-risk antibiotic use in relation to hospital-associated Clostridioides difficile infections: retrospective analysis of 2016–2017 data from US hospitals. Infect Control Hosp Epidemiol. 2019;40(11):1229–1235.
- McDonald LC, Gerding DN, Johnson S, et al. Clinical practice guidelines for clostridium difficile infection in adults and children: 2017 update by the infectious diseases society of america (IDSA) and society for healthcare epidemiology of america (SHEA). Clin Infect Dis. 2018;66(7):e1–e48.
- Johnson C Therapeutic guidelines: psychotropic. version 6. 2009. [cited 2021 Jun 10]. Available from: https://doi.org/10.18773/austprescr.2009.021
- Phan SV, Osae S, Morgan JC, et al. Neuropsychiatric symptoms in dementia: considerations for pharmacotherapy in the USA. Drugs R D. 2019;19(2):93–115.
- Mathew P, Thoppil D. Hypoglycemia. StatPearls. Treasure Island (FL): StatPearls Publishing Copyright © 2022, StatPearls Publishing LLC.; 2022.
- Shrestha S, Shrestha S, Khanal S. Polypharmacy in elderly cancer patients: challenges and the way clinical pharmacists can contribute in resource-limited settings. Aging Med (Milton). 2019;2(1):42–49.
- Schmader KE, Hanlon JT, Pieper CF, et al. Effects of geriatric evaluation and management on adverse drug reactions and suboptimal prescribing in the frail elderly. Am J Med. 2004;116(6):394–401.
- Ali S, Salahudeen MS, Bereznicki LRE, et al. Pharmacist‐led interventions to reduce adverse drug events in older people living in residential aged care facilities: a systematic review. Br J Clin Pharmacol. 2021;87(10):3672–3689.
- Royal Commission into Aged Care Quality and Safety. A summary of the final report. 2021. [Accessed 2021 May 10]. Available from: https://agedcare.royalcommission.gov.au/sites/default/files/2021-03/final-report-executive-summary.pdf
- Jordan S, Banner T, Gabe-Walters M, et al. Nurse-led medicines’ monitoring in care homes, implementing the Adverse Drug Reaction (ADRe) profile improvement initiative for mental health medicines: an observational and interview study. PLoS One. 2019;14(9):e0220885–e.
- Jordan S, Gabe-Walters ME, Watkins A, et al. Nurse-led medicines’ monitoring for patients with dementia in care homes: a pragmatic cohort stepped wedge cluster randomised trial. PLoS One. 2015;10(10):e0140203.
- Liao P-J, Mao C-T, Chen T-L, et al. Factors associated with adverse drug reaction occurrence and prognosis, and their economic impacts in older inpatients in Taiwan: a nested case–control study. BMJ Open. 2019;9(5):e026771.
- Zhang M, Holman CDAJ, Price SD, et al. Comorbidity and repeat admission to hospital for adverse drug reactions in older adults: retrospective cohort study. BMJ. 2009;338:a2752.
- Merle L, Laroche ML, Dantoine T, et al. Predicting and preventing adverse drug reactions in the very old. Drugs Aging. 2005;22(5):375–392.
- Passarelli MC, Jacob-Filho W, Figueras A. Adverse drug reactions in an elderly hospitalised population: inappropriate prescription is a leading cause. Drugs Aging. 2005;22(9):767–777.