Evaluation of Theophylline-Stimulated Changes in Carnitine Palmitoyltransferase Activity in Skeletal Muscle and Liver of Rats

References

• McGarry J. D., Faster C. A. Regulation of hepatic fatty acid oxidation and ketone body production. Ann. Rev. Biochem. 1980; 49: 395–420
   PubMed Web of Science ®Google Scholar
• Pande S. V., Brivet M., Slama A., Demaugre F., Aufrant C., Saudubray J. Carnitine-acylcarnitine translo-case deficiency with severe hypoglycemia and auriculo-ventricular block. Translocase assay in permeabilized fibroblasts. J. Clin. Invest. 1993; 91: 1247–1252
   Google Scholar
• Guzman M., Geelen M. J.H. Short-term regulation of carnitine palmitoyltransferase activity in isolated rat hepatocytes. Biochem. Biophys. Res. Commun. 1988; 151: 781–787
   Google Scholar
• Bremer J. The effect of fasting on the activity of liver carnitine palmitoyltransferase and its inhibition by malonyl-CoA. Biochem. Biophys. Acta. 1981; 665: 628–631
   PubMed Web of Science ®Google Scholar
• Cook G. A., Gamble M. S. Regulation of carnitine palmitoyltransferase by insulin results in decreased activity and decreased K1 for malonyl-CoA. J. Biol. Chem. 1987; 262: 2050–2055
   Google Scholar
• Brady P. S., Brady L. J. Regulation of carnitine palmitoyltransferase in vivo by insulin and glucagon. Biochem. J. 1989; 258: 677–682
   Google Scholar
• Weinstein I., Cook G. A., Heimberg M. Regulation by oestrogen of carnitine palmitoyltransferase in hepatic mitochondria. Biochem. J. 1986; 237: 593–569
   Google Scholar
• Di Mauro S., Di Mauro P. M.M. Muscle carnitine palmitoyltransferase deficiency and myoglobinuria. Science 1973; 182: 929–931
   Google Scholar
• Bougneres P. F., Saudubray J. M., Marsac C., Bernard O., Odi ver M., Girard J. Fasting hypoglycemia resulting from hepatic carnitine palmitoyltransferase deficiency. J. Pediatr. 1981; 98: 742–746
   Google Scholar
• Aranda J. V., Turmen T. Methylxanthines in apnea of prematurity. Clin. Perinatol. 1979; 6: 87–107
   PubMed Web of Science ®Google Scholar
• Woo O. F., Pond S. M., Benowitz N. J., Olson K. R. Benefit of hemoperfusion in acute theophylline intoxication. Clin. Toxicol 1984; 22: 411–424
   Web of Science ®Google Scholar
• Supinski G. S., Chandler D., Kelson S. G. The effects of caffeine and theophylline on diaphragm contractility. Am. Rev. Respir. Des. 1984; 130: 429–433
   PubMed Web of Science ®Google Scholar
• Rail T. W. Central nervous system stimulants: the methylxanthines in The Pharmacological Basis of Therapeutics, A. G. Gilman, L. S. Goodman, T. W. Rail, F. Murad. MacMillan Publishing Co, New York 1985; 589–595
   Google Scholar
• Fredholm B. B., Lindgren E. The effect of alkylxanthines and other phosphodiesterase inhibitors on adenosine-receptor mediated decrease in lipolysis and cyclic AMP accumulations in rat fat cells. Acta. Pharmacol. Toxicol. 1984; 54: 64–71
   Google Scholar
• Al-Jafari A. A., Junaid M. A., Alhomida A. S. Investigation of the influence of theophylline feeding on total, free, short-chain acyl and long-chain acyl carnitine levels in skeletal muscle and liver of rats. In vivo 1966; 10: 569–574
   Google Scholar
• Al-Kholaifi A. M., Alhomida A. S. Evaluation of theophylline-induced changes on plasma total, free, short-chain acyl and long-chain acyl carnitine concentrations in rats. Med. Sci. Res. 1997; 25: 31–34
   Google Scholar
• Alhomida A. S. Study of the effects of theophyl-line-related changes in total, free, short-chain acyl and long-chain acyl carnitine concentrations in rat heart. Toxicology 1997; 121: 205–213
   Google Scholar
• Bieber L. L., Abraham T., Helmrah T. A rapid spectrophotometric assay for carnitine palmitoyltransferase. Anal. Biochem. 1972; 50: 509–518
   PubMed Web of Science ®Google Scholar
• Lilienthal J. L., Zierler K. L., Folk B. P., Buka R., Riley M. J. A reference base and system for analysis of muscle constituents. J. Biol. Chem. 1950; 182: 501–508
   Google Scholar
• Markwell M. A.K., Haes S. M., Tolbert N. E., Bieber L. L. Protein determination in membrane and lipoprotein samples: manual and automated procedures. Meth. Enzymol. 1981; 72: 269–303
   Google Scholar
• Alhomida A. S. Investigation of the effect of theophylline administration on total, free, short-chain acyl and long-chain acyl carnitine distributions in rat renal tissues. Cell Biochem. Func. 1998; 16: 165–171
   Google Scholar
• Scammell J. G., Fregly M. J. Effect of theophylline on thyroid status in the rat. Pharmacol. 1982; 25: 160–169
   Google Scholar
• Saggerson E. D., Carpenter C. A. Carnitine palmitoyltransferase and carnitine octanoyltransferase activities in liver, kidney cortex, adipocyte, lactating mammary gland, skeletal muscle and heart. Relative activities, latency and effect of malonyl-CoA. FEBS Lett. 1981; 129: 229–232
   PubMed Web of Science ®Google Scholar
• Saggerson E. D. Carnitine palmitoyltransferase in extrahepatic tissues. Biochem. Soc. Trans. 1986; 14: 679–681
   Google Scholar
• Saggerson E. D., Carpenter C. A. Carnitine palmitoyltransferase in liver and five extrahepatic tissues. Inhibition by DL-2-bromopalmitoyl-CoA and effect of hypothyroidism. Biochem. J. 1981; 236: 137–141
   Google Scholar
• McGarry J. D., Mills S. E., Long C. S., Foster D. W. Observations on the affinity for carnitine, and malonyl-CoA sensitivity, of carnitine palmitoyltransferase I in animal and human tissues. Biochem. J. 1983; 214: 21–28
   PubMed Web of Science ®Google Scholar
• Miller M., Opheim K. E., Raisys V. A., Motulsky A. G. Theophylline metabolism: variation and genetics. Clin. Pharm. Titer. 1992; 35: 170–182
   Google Scholar
• Cook G. A., Lappi M. D. Carnitine palmitoyltransferase in the heart is controlled by a different mechanism than the hepatic enzyme. Biochem. J. 1992; 116: 39–45
   Google Scholar
• Saggerson E. D., Ghadiminejad I., Awan M. Regulation of mitochondrial carnitine palmitoyltransferases from liver and extrahepatic tissues. Adv. Enzyme Regul. 1992; 32: 285–306
   Google Scholar