737
Views
34
CrossRef citations to date
0
Altmetric
Research Article

Carbonic anhydrase inhibitors. Cloning, characterization and inhibition studies of the cytosolic isozyme III with anions

, , , , , & show all
Pages 70-76 | Received 28 Jun 2007, Accepted 26 Nov 2007, Published online: 20 Oct 2008

References

  • CT Supuran, A Scozzafava, and A Casini. (2003). Carbonic anhydrase inhibitors. Med Res Rev 23:146–189.
  • S Pastorekova, S Parkkila, J Pastorek, and CT Supuran. (2004). Carbonic anhydrases: Current state of the art, therapeutic applications and future prospects. J Enz Inhib Med Chem 19:199–229.
  • M Hilvo, CT Supuran, and S Parkkila. (2007). Characterization and inhibition of the recently discovered carbonic anhydrase isoforms CA XIII, XIV and XV. Curr Top Med Chem 7:893–899.
  • CT Supuran, and A Scozzafava. (2007). Carbonic anhydrases as targets for medicinal chemistry. Bioorg Med Chem 15:4336–4350.
  • RS Rowlett, NJ GargiuloIII, FA Santoli, JM Jackson, and AH Corbett. (1991). Activation and inhibition of bovine carbonic anhydrasde III by dianions. J Biol Chem 266:933–941.
  • AE Eriksson, and A Liljas. (1993). Refined structure of bovine carbonic anhydrase III at 2.0 A resolution. Proteins 16:29–42.
  • PJ Wistrand. (2002). Carbonic anhydrase III in liver and muscle of male rats purification and properties. Ups J Med Sci 107:77–88.
  • M Liu, GA Walter, NC Pathare, RE Forster, and K Vandenborne. (2007). A quantitative study of bioenergetics in skeletal muscle lacking carbonic anhydrase III using 31P magnetic resonance spectroscopy. Proc Natl Acad Sci USA 104:371–376.
  • L Li, and CN Falany. (2007). Elevated hepatic SULT1E1 activity in mouse models of cystic fibrosis alters the regulation of estrogen responsive proteins. J Cyst Fibros 6:23–30.
  • T Yamamoto, R Kikkawa, H Yamada, and I Horii. (2006). Investigation of proteomic biomarkers in in vivo hepatotoxicity study of rat liver: Toxicity differentiation in hepatotoxicants. J ToxicolSci 31:49–60.
  • UJ Zimmerman, P Wang, X Zhang, S Bogdanovich, and R Forster. (2004). Anti-oxidative response of carbonic anhydrase III in skeletal muscle. IUBMB Life 56:343–347.
  • SR Räisänen, P Lehenkari, M Tasanen, P Rahkila, PL Härkönen, and HK Väänänen. (1999). Carbonic anhydrase III protects cells from hydrogen peroxide-induced apoptosis. FASEB J 13:513–522.
  • GA Gill, N Johnston, A Buda, M Pignatelli, J Pearson, PW Dettmar, and J Koufman. (2005). Laryngeal epithelial defenses against laryngopharyngeal reflux: Investigations of E-cadherin, carbonic anhydrase isoenzyme III, and pepsin. Ann Otol Rhinol Laryngol 114:913–921.
  • G Kim, and RL Levine. (2005). Molecular determinants of S-glutathionylation of carbonic anhydrase III. Antioxid Redox Signal 7:849–854.
  • RJ Mallis, MJ Hamann, W Zhao, T Zhang, S Hendrich, and JA Thomas. (2002). Irreversible thiol oxidation in carbonic anhydrase III: Protection by S-glutathiolation and detection in aging rats. Biol Chem 383:649–662.
  • CJ Lynch, WA Brennan, TC Vary, N Carter, and SJ Dodgson. (1993). Carbonic anhydrase III in obese Zucker rats. Am J Physiol 264:E621–E630.
  • A Alver, F Uçar, EE Keha, E Kalay, and E Ovali. (2004). Effects of leptin and insulin on CA III expression in rat adipose tissue. J Enz Inhib Med Chem 19:279–281.
  • A Alver, EE Keha, F Uçar, and E Ovali. (2004). The effect of carbonic anhydrase inhibition on leptin secretion by rat adipose tissue. J Enz Inhib Med Chem 19:181–184.
  • CT Supuran. (2003). Carbonic anhydrase inhibitors in the treatment and prophylaxis of obesity. Expert Opin Ther Pat 13:1545–1550.
  • G De Simone, and CT Supuran. (2007). Antiobesity carbonic anhydrase inhibitors. Curr Top Med Chem 7:879–884.
  • N Carter, A Shiels, and R Tashian. (1978). Carbonic anhydrase III isoenzyme from human and bovine muscle. Biochem Soc Trans 6:552–553.
  • I Nishimori, D Vullo, A Innocenti, A Scozzafava, A Mastrolorenzo, and CT Supuran. (2005). Carbonic anhydrase inhibitors. The mitochondrial isozyme VB as a new target for sulfonamide and sulfamate inhibitors. J Med Chem 48:7860–7866.
  • S Pastorekova, D Vullo, A Casini, A Scozzafava, J Pastorek, I Nishimori, and CT Supuran. (2005). Carbonic anhydrase inhibitors: Inhibition of the tumor-associated isozymes IX and XII with polyfluorinated aromatic/heterocyclic sulfonamides. J Enz Inhib Med Chem 20:211–217.
  • D Vullo, A Innocenti, I Nishimori, J Pastorek, A Scozzafava, S Pastorekova, and CT Supuran. (2005). Carbonic anhydrase inhibitors. Inhibition of the transmembrane isozyme XII with sulfonamides-a new target for the design of antitumor and antiglaucoma drugs?. Bioorg Med Chem Lett 15:963–969.
  • I Nishimori, T Minakuchi, S Onishi, D Vullo, A Cecchi, A Scozzafava, and CT Supuran. (2007). Carbonic anhydrase inhibitors: Cloning, characterization, and inhibition studies of the cytosolic isozyme III with sulfonamides. Bioorg Med Chem 15:7229–7236.
  • RG Khalifah. (1971). The carbon dioxide hydration activity of carbonic anhydrase. I. Stop-flow kinetic studies on the native human isoenzymes B and C. J Biol Chem 246:2561–2573.
  • RE Tashian. (1992). Genetics of the mammalian carbonic anhydrases. Adv. Genet 30:321–356.
  • CT Supuran, A Scozzafava, and J Conway. Carbonic Anhydrase – Its Inhibitors and Activators. Boca Raton, New York, London: CRC Press; (2004). p 1–363.
  • PA Boriack-Sjodin, S Zeitlin, HH Chen, L Crenshaw, S Gross, A Dantanarayana, P Delgado, JA May, T Dean, and DW Christianson. (1998). Structural analysis of inhibitor binding to human carbonic anhydrase II. Protein Sci 7:2483–2489.
  • G De Simone, A Di Fiore, V Menchise, C Pedone, J Antel, A Casini, A Scozzafava, M Wurl, and CT Supuran. (2005). Carbonic anhydrase inhibitors. Zonisamide is an effective inhibitor of the cytosolic isozyme II and mitochondrial isozyme V: Solution and X-ray crystallographic studies. Bioorg Med Chem Lett 15:2315–2320.
  • C Temperini, A Scozzafava, and CT Supuran. (2006). Carbonic anhydrase activators: The first X-ray crystallographic study of an adduct of isoform I. Bioorg Med Chem Lett 16:5152–5156.
  • D Vullo, M Franchi, E Gallori, J Pastorek, A Scozzafava, S Pastorekova, and CT Supuran. (2003). Carbonic anhydrase inhibitors. Inhibition of cytosolic isozymes I and II and transmembrane, cancer-associated isozyme IX with anions. J Enz Inhib Med Chem 18:403–406.
  • A Innocenti, JM Lehtonen, S Parkkila, A Scozzafava, and CT Supuran. (2004). Carbonic anhydrase inhibitors. Inhibition of the newly isolated murine isozyme XIII with anions. Bioorg Med Chem Lett 14:5435–5439.
  • F Abbate, CT Supuran, A Scozzafava, P Orioli, MT Stubbs, and G Klebe. (2002). Nonaromatic sulfonamide group as an ideal anchor for potent human carbonic anhydrase inhibitors: Role of hydrogen-bonding networks in ligand binding and drug design. J Med Chem 45:3583–3587.
  • A Innocenti, D Vullo, A Scozzafava, and CT Supuran. (2005). Carbonic anhydrase inhibitors. Inhibition of isozymes I, II, IV, V and IX with anions isosteric and isoelectronic with sulfate, nitrate and carbonate. Bioorg Med Chem Lett 15:567–571.
  • MA Ilies, and MD Banciu. Nonsulfonamide carbonic anhydrase inhibitors In: CT Supuran, A Scozzafava, and J Conway. editors. Carbonic anhydrase - Its inhibitors and activators. Boca Raton (FL), USA: CRC Press; (2004). p 209–242.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.