245
Views
17
CrossRef citations to date
0
Altmetric
Original Research

Seasonal influenza vaccination and absenteeism in health-care workers in two subsequent influenza seasons (2016/17 and 2017/18) in an Italian pediatric hospital

, , , , , , , , & show all
Pages 411-418 | Received 12 Jan 2019, Accepted 21 Feb 2019, Published online: 28 Mar 2019

References

  • Restivo V, Costantino C, Bono S, et al. Influenza vaccine effectiveness among high-risk groups: A systematic literature review and meta-analysis of case-control and cohort studies. Hum Vaccin Immunother. 2018 Mar;4:14(3):724–735.
  • Osterholm MT, Kelley NS, Sommer A, et al. Efficacy and effectiveness of influenza vaccines: a systematic review and meta-analysis. Lancet Infect Dis. 2012;12:36–44.
  • Centers for Disease Control and Prevention. Immunization of healthcare personnel:recommendations of the ACIP. MMWR Recomm Rep. 2011;60(RR–07):1–45.
  • Kliner M, Keenan A, Sinclair D, et al. Influenza vaccination for healthcare workers in the UK: appraisal of systematic reviews and policy options. BMJ Open. 2016;6:e012149.
  • Ahmed F, Lindley M, Allred N, et al. Effect of influenza vaccination of health care personnel on morbidity and mortality among patients: systematic review and grading of evidence. Clin Infect Dis. 2013. DOI:10.1093/cid/cit580
  • De Serres G, Skowronski DM, Ward BJ, et al. Influenza vaccination of healthcare workers: critical analysis of the evidence for patient benefit underpinning policies of enforcement. PLoS One. 2017 Jan 27;12(1):e0163586.
  • Thomas RE, Jefferson T, Lasserson TJ. Influenza vaccination for healthcare workers who care for people aged 60 or older living in long-term care institutions. Cochrane Database Syst Rev. 2016 Jun 2;(6):CD005187. DOI:10.1002/14651858.CD005187.pub5
  • Carman WF, Elder A, Wallace LA, et al. Effects of influenza vaccination of health-care workers on mortality of elderly people in long-term care: a randomized controlled trial. Lancet. 2000;355:93–97.
  • Amodio E, Restivo V, Firenze A, et al. Can influenza vaccination coverage among healthcare workers influence the risk of nosocomial influenza-like illness in hospitalized patients? J Hosp Infect. 2014 Mar;86(3):182–187.
  • Hayward AC, Harling R, Wetten S, et al. Effectiveness of an influenza vaccine programme for care home staff to prevent death, morbidity, and health service use among residents: cluster randomized controlled trial. BMJ. 2006;333(7581):1241.
  • Lemaitre M, Meret T, Rothan-Tondeur M, et al. Effect of influenza vaccination of nursing homes staff on mortality of residents: acluster randomized trial. J Am Geriatr Soc. 2009;57(9):1580–1586.
  • Potter J, Stott DJ, Roberts MA, et al. Influenzavaccination of health care workers in long-term-care hospitals reduces mor-tality of elderly patients. J Infect Dis. 1997;157(1):1–6.
  • Benet T, Regis C, Voirin N, et al. Infleunza vac-cination of healthcare workers in acute-care hospitals: a case–control study of its effect on hospital-acquired influenza among patients. BMC Infect Dis. 2012;12:30.
  • Ting EEK, Sander B, Ungar WJ. Systematic review of the cost-effectiveness of influenza immunization programs. Vaccine. 2017;35:1828–1843.
  • Gianino MM, Politano G, Scarmozzino A, et al. Estimation of sickness absenteeism among Italian healthcare workers during seasonal influenza epidemics. PLoS One. 2017 Aug 9;12(8):e0182510.
  • Ip DKM, Lau EHY, Tam YH, et al. Increases in absenteeism among healthcare workers in Hong Kong during influenza epidemics, 2004±2009. BMC Infect Dis. 2015;15:586.
  • Schanzer DL, Zheng H, Gilmore J. Statistical estimates of absenteeism attributable to seasonal and pandemic influenza from the Canadian Labour Force Survey. BMC Infect Dis. 2011;11:90.
  • Amodio E, Anastasi G, Di Pasquale M, et al. Influenza vaccination among healthcare workers and absenteeism from work due to influenza-like illness in a teaching hospital in Palermo. Ijph. 2010;7(3). DOI:10.2427/5715.
  • Keech M, Beardsworth P. The impact of influenza on working days lost: a review of the literature. Pharmacoeconomics. 2008;26(11):911–924.
  • Colombo GL, Ferro A, Vinci M, et al. Cost-benefit analysis of influenza vaccination in a public healthcare unit. Ther Clin Risk Manag. 2006;2(2):219–226.
  • O’Reilly FW, Stevens AB. Sickness absence due to influenza. Occup Med Oxf Engl. 2002;52(5):265±9.
  • Hammond GW, Cheang M. Absenteeism among hospital staff during an influenza epidemic: implications for immunoprophylaxis. Can Med Assoc J. 1984;131(5):449±52.
  • Nguyen-Van-Tam J, Granfield R, Pearson J, et al. Do influenza epidemics affect patterns of sickness absence among British hospital staff? Infect Control Hosp Epidemiol. 1999;20(10):691–694.
  • Pereira M, Williams S, Restrick L, et al. London respiratory network. Healthcare worker influenza vaccination and sickness absence - an ecological study. Clin Med (Lond). 2017 Dec;17(6):484–489.
  • Olsen GW, Burris JM, Burlew MM, et al. Absenteeism among employees who participated in a workplace influenza immunization program. J Occup Environ Med. 1998;40(4):311–6.
  • European Centre for Disease Prevention and Control. Seasonal influenza vaccination in Europe - vaccination recommendations and coverage rates in the EU member states for eight influenza seasons: 2007–2008 to 2014–2015. Stockholm, Sweden: ECDC; 2017.
  • Italian Ministry of Health. Prevention and control of influenza: recommendations for 2017–2018 influenza season. 2017. [ cited 2019 Jan 6]. Available from: http://www.salute.gov.it/portale/news/p3_2_1_1_1.jsp?menu=notizie&id=3037
  • Italian Health Ministry. National Preventive Vaccination Plan 2017–2019.
  • Costantino C, Restivo V, Gaglio V, et al. Effectiveness of an educational intervention on seasonal influenza vaccination campaign adherence among healthcare workers of the Palermo University Hospital, Italy. Ann Ig. 2019 Jan-Feb;31(1):35–44.
  • Alicino C, Iudici R, Barberis I, et al. Nfluenza vaccination among healthcare workers in Italy. Hum Vaccin Immunother. 2015;11(1):95–100.
  • Levi M, Bonanni P, Biffino M, et al. Influenza vaccination 2014–2015: results of a survey conducted among general practitioners in Italy. Hum Vaccin Immunother. 2018;14(6):1342–1350.
  • Vasilevska M, Ku J, Fisman DN. Factors associated with healthcare worker acceptance of vaccination: a systematic review and meta-analysis. Infect Control Hosp Epidemiol. 2014 Jun;35(6):699–708.
  • Smedley J, Poole J, Waclawski E, et al. Influenza immunisation: attitudes and beliefs of UK healthcare workers. Occup Environ Med. 2007 Apr;64(4):223–227.
  • Schmid P, Rauber D, Betsch C, et al. Barriers of influenza vaccination intention and behavior – a systematic review of influenza vaccine hesitancy, 2005 – 2016. PloS ONE. 2017;12(1):e0170550.
  • Karafillakis E, Dinca I, Apfel F, et al. Vaccine hesitancy among healthcare workers in Europe: A qualitative study. Vaccine. 2016 Sep 22;34(41):5013–5020.
  • Dini G, Toletone A, Sticchi L, et al. Influenza vaccination in healthcare workers: A comprehensive critical appraisal of the literature. Hum Vaccin Immunother. 2018 Mar 4;14(3):772–789.
  • Conte A, Quattrin R, Filiputti E, et al. Promotion of flu vaccination among healthcare workers in an Italian academic hospital: an experience with tailored web tools. Hum Vaccin Immunother. 2016 Oct 2;12(10):2628–2633.
  • Durando P, Alicino C, Dini G, et al. Determinants of adherence to seasonal influenza vaccination among healthcare workers from an Italian region: results from a cross-sectional study. BMJ Open. 2016 May 17;6(5):e010779.
  • Barbadoro P, Marigliano A, Di Tondo E, et al. Determinants of influenza vaccination uptake among Italian healthcare workers. Hum Vaccin Immunother. 2013 Apr;9(4):911–916.
  • Black CL, Yue X, Ball SW, et al. Influenza vaccination coverage among health care personnel—united States, 2016–2017 influenza season. Morb Mortal Wkly Rep. 2017;66:1009–1015.
  • Wicker S, Marckmann G. Vaccination of health care workers against influenza is it time to think about a mandatory policy in Europe? Vaccine. 2014 Aug 27;32(38):4844–4848.
  • Quach S, Pereira JA, Kwong JC, et al. Public Health Agency of Canada/Canadian Institutes of Health Research Influenza Research Network (PCIRN) program delivery and evaluation theme group. Immunizing health care workers against influenza: a glimpse into the challenges with voluntary programs and considerations for mandatory policies. Am J Infect Control. 2013 Nov;41(11):1017–1023.
  • Steckel CM. Mandatory influenza immunization for health care workers - an ethical discussion. AAOHN J. 2007 Jan;55(1):34–39.
  • Frederick J, Brown AC, Derek A, et al. Protecting healthcare personnel in outpatient settings: the influence of mandatory versus nonmandatory influenza vaccination policies on workplace absenteeism during multiple respiratory virus seasons. Infect Control Hosp Epidemiol. 2018;1. DOI:10.1017/ice.2018.9.
  • McCartney M. Mandatory flu vaccination won’t fix the NHS. BMJ. 2018;360. DOI:10.1136/bmj.k402
  • Rizzo C, Rezza G, Ricciardi W. Strategies in recommending influenza vaccination in Europe and US. Hum Vaccin Immunother. 2018;14(3):693–698.
  • World Health Organization. Tailoring Immunization Programmes for Seasonal Influenza (TIP FLU). A guide for increasing health care workers’ uptake of seasonal influenza vaccination. Copenhagen: WHO Regional Office for Europe; 2015.
  • Nutman A, Yoeli N. Influenza vaccination motivators among health care personnel in a large acute care hospital.Israel. J Health Policy Res. 2016;5:52.
  • Barbara A, Giubbini G, De Waure C, et al. Is the on site flu vaccination among health care workers effective? A Italian teaching hospital case. Eur J Public Health. 2017;27(Supplement 3). DOI:10.1093/eurpub/ckx187.380
  • Lytras T, Kopsachilis F, Mouratidou E, et al. BonovasS. Interventions to increase seasonal influenza vaccine coverage in healthcare workers: A systematic review and meta-regression analysis. Hum Vaccin Immunother. 2016 Mar 3;12(3):671–681.
  • Schmidt S, Saulle R, Di Thiene D, et al. Do the quality of the trials and the year of publication affect the efficacy of intervention to improve seasonal influenza vaccination among healthcare workers?: results of a systematic review. Hum Vaccin Immunother. 2013 Feb;9(2):349–361.
  • Gilardi F, Castelli Gattinara G, Vinci MR, et al. Seasonal influenza vaccination in health care workers. A pre-post intervention study in an italian paediatric hospital. Int J Environ Res Public Health. 2018;15:841.
  • World Health Organization. Pandemic influenza Risk management. [ cited 2018 Dec 10]. Available from: https://www.who.int/influenza/preparedness/pandemic/PIRM_update_052017.pdf
  • Imai C, Toizumi M, Hall L, et al. A systematic review and meta-analysis of the direct epidemiological and economic effects of seasonal influenza vaccination on healthcare workers. PLoS One. 2018 Jun 7;13(6):e0198685.
  • Akazawa M, Sindelar JL, Paltiel AD. Economic costs of influenza-related work absenteeism. Value Health J Int Soc PharmacoEcon Outcomes Res. 2003;6(2):107–15.
  • Laris González A, Villa Guillén M, López Martínez B, et al. Influenza-like illness in healthcare personnel at a paediatric referral hospital: clinical picture and impact of the disease. Influenza Other Respi Viruses. 2018;12:475–481.
  • National sentinel surveillance system (INFLUNET). [cited 2018 Dec 10]. Available from https://old.iss.it/site/RMI/influnet/pagine/stagioni.aspx.
  • Mota NV, Lobo RD, Toscano CM, et al. Cost effectiveness of sick leave policies for health care workers with influenza-like illness, Brazil, 2009. Emerg Infect Dis. 2011;17(8):1421–1429.
  • Van Buynder PG, Konrad S, Kersteins F, et al. Healthcare worker influenza immunization vaccinate or mask policy: strategies for cost effective implementation and subsequent reductions in staff absenteeism due to illness. Vaccine. 2015;33(13):1625–8.
  • Chan ALF, Shie H-J, Lee Y-J, et al. The evaluation of free influenza vaccination in health care workers in a medical center in Taiwan. Pharm World Sci. 2008;30(1):39–43.
  • Postma MJ, Jansema P, Scheijbeler HWKFH, et al. Scenarios on costs and savings of influenza treatment and prevention for Dutch healthy working adults. Vaccine. 2005;23(46–47):5365–5371.
  • Candace LS, Elizabeth RC, Donna AD, et al. The decision-making process of workers in using sick time. Workplace Health Saf. 2014;62(8):318–324.
  • Piper K, Youk A, James III AE, et al. Paid sick days and stay-at-home behavior for influenza. PLos One. 2017;12(2):e0170698.
  • Poul F, Jens PH, Johan HA. Impact of work, health and health beliefs on new episodes of pain-related and general absence-taking. Scand J Public Health. 2009;37(6):569–576.
  • Tan PC, Robinson G, Jayathissa S, et al. Coming to work sick: a survey of hospital doctors in New Zealand. NZ Med J. 2014;127(1399):23–35.
  • Gustafsson Senden M, Lovseth LT, Schenck-Gustafsson K, et al. What makes physicians go to work while sick: a comparative study of sickness presenteeism in four European countries (HOUPE). Swiss Med Wkly. 2013;143:w13840.
  • Giæver F, Lohmann-Lafrenz S, Løvseth LT. Why hospital physicians attend work while ill? The spiraling effect of positive and negative factors. BMC Health Serv Res. 2016;16:548.
  • Thompson MG, Naleway A, Fry AM, et al. Effects of repeated annual inactivated influenza vaccination among healthcare personnel on serum hemagglutinin inhibition antibody response to A/Perth/16/2009 (H3N2)-like virus during 2010–11. Vaccine. 2016;34(7):981–988.
  • Saito N, Komori K, Suzuki M, et al. Negative impact of prior influenza vaccination on current influenza vaccination among people infected and not infected in prior season: A test-negative case-control study in Japan. Vaccine. 2017;35(4):687–693.
  • Cheng AC, MaCartney KK, Waterer GW, et al. Repeated vaccination does not appear to impact upon influenza vaccine effectiveness against hospitalization with confirmed influenza. Clin Infect Dis. 2017;64(11):1564–1572.
  • Belongia EA, Simpson MD, King JP, et al. Variable influenza vaccine effectiveness by subtype: a systematic review and meta-analysis of test-negative design studies. Lancet Infect Dis. 2016;16(8):942–951.
  • Skowronski DM, Chambers C, De Serres G, et al. Early season co-circulation of influenza A(H3N2) and B(Yamagata): interim estimates of 2017/18 vaccine effectiveness, Canada, January 2018. Euro Surveill. 2018;23(5):18–00035.
  • Flannery B, Chung JR, Belongia EA, et al. Interim estimates of 2017-18 seasonal influenza vaccine effectiveness - United States, February 2018. MMWR Morb Mortal Wkly Rep. 2018;67(6):180–185.
  • Castilla J, Navascués A, Casado I, et al. Interim effectiveness of trivalent influenza vaccine in a season dominated by lineage mismatched influenza B, northern Spain, 2017/18. Euro Surveill. 2018;23(7):18–00057.
  • Rondy M, Kissling E, Emborg HD, et al. Interim 2017/18 influenza seasonal vaccine effectiveness: combined results from five European studies. Euro Surveill. 2018 Mar;23(9). M; I-MOVE/I-MOVE+ group. DOI:10.2807/1560-7917.ES.2018.23.9.18-00086.
  • Skowronski DM, Janjua NZ, De Serres G, et al. Low 2012–13 influenza vaccine effectiveness associated with mutation in the egg-adapted H3N2 vaccine strain not antigenic drift in circulating viruses. PLoS ONE. 2014;9(3):e92153.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.