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Expert Review of Vaccines Volume 21, 2022 - Issue 12
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Original Research

The impact of vaccination on the burden of invasive pneumococcal disease from a nationwide surveillance program in Lebanon: an unexpected increase in mortality driven by non-vaccine serotypes

Lina Reslana Center for Infectious Diseases Research (CIDR) and WHO Collaborating Center for Reference and Research on Bacterial Pathogens, American University of Beirut, Beirut, LebanonView further author information
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Nour Youssefa Center for Infectious Diseases Research (CIDR) and WHO Collaborating Center for Reference and Research on Bacterial Pathogens, American University of Beirut, Beirut, Lebanon;b Department of Pediatrics and Adolescent Medicine, American University of Beirut, Faculty of Medicine, Beirut, LebanonView further author information
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Celina F. Boutrosa Center for Infectious Diseases Research (CIDR) and WHO Collaborating Center for Reference and Research on Bacterial Pathogens, American University of Beirut, Beirut, LebanonORCID Iconhttps://orcid.org/0000-0001-7789-8478View further author information
ORCID Icon,
Aia Assaf-Casalsa Center for Infectious Diseases Research (CIDR) and WHO Collaborating Center for Reference and Research on Bacterial Pathogens, American University of Beirut, Beirut, Lebanon;b Department of Pediatrics and Adolescent Medicine, American University of Beirut, Faculty of Medicine, Beirut, LebanonView further author information
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Danielle Fayada Center for Infectious Diseases Research (CIDR) and WHO Collaborating Center for Reference and Research on Bacterial Pathogens, American University of Beirut, Beirut, LebanonView further author information
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Sarah Khafajaa Center for Infectious Diseases Research (CIDR) and WHO Collaborating Center for Reference and Research on Bacterial Pathogens, American University of Beirut, Beirut, Lebanon;b Department of Pediatrics and Adolescent Medicine, American University of Beirut, Faculty of Medicine, Beirut, LebanonView further author information
,
Fata Akla Center for Infectious Diseases Research (CIDR) and WHO Collaborating Center for Reference and Research on Bacterial Pathogens, American University of Beirut, Beirut, LebanonView further author information
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Marc Finianosa Center for Infectious Diseases Research (CIDR) and WHO Collaborating Center for Reference and Research on Bacterial Pathogens, American University of Beirut, Beirut, Lebanon;c Department of Microbiology, Faculty of Medicine, and University Hospital in Pilsen, Charles University, Pilsen, Czech Republic;d Biomedical Center, Faculty of Medicine, Charles University, Pilsen, Czech RepublicView further author information
,
Amena A. Rizka Center for Infectious Diseases Research (CIDR) and WHO Collaborating Center for Reference and Research on Bacterial Pathogens, American University of Beirut, Beirut, LebanonView further author information
,
Rouba Shakera Center for Infectious Diseases Research (CIDR) and WHO Collaborating Center for Reference and Research on Bacterial Pathogens, American University of Beirut, Beirut, Lebanon;b Department of Pediatrics and Adolescent Medicine, American University of Beirut, Faculty of Medicine, Beirut, LebanonView further author information
,
Alissar Zaghlouta Center for Infectious Diseases Research (CIDR) and WHO Collaborating Center for Reference and Research on Bacterial Pathogens, American University of Beirut, Beirut, LebanonView further author information
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Mireille Lteifa Center for Infectious Diseases Research (CIDR) and WHO Collaborating Center for Reference and Research on Bacterial Pathogens, American University of Beirut, Beirut, LebanonView further author information
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Bassam El Hafia Center for Infectious Diseases Research (CIDR) and WHO Collaborating Center for Reference and Research on Bacterial Pathogens, American University of Beirut, Beirut, Lebanon;e Department of Experimental Pathology, Immunology, and Microbiology, Faculty of Medicine, American University of Beirut, Beirut, LebanonORCID Iconhttps://orcid.org/0000-0003-3277-2948View further author information
ORCID Icon,
Mohammad Bahij Moumneha Center for Infectious Diseases Research (CIDR) and WHO Collaborating Center for Reference and Research on Bacterial Pathogens, American University of Beirut, Beirut, LebanonView further author information
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Rita Feghalif Department of Laboratory Medicine, Rafik Hariri University Hospital, Beirut, LebanonView further author information
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Soha Ghanemg Department of Pediatrics, Makassed General Hospital, Beirut, Lebanon;h Department of Pediatrics, Saint Georges Hospital University Medical Center, Achrafieh, Beirut, LebanonView further author information
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Tamima Jisri Laboratory medicine and transfusion medicine department, Makassed General Hospital, Beirut, LebanonView further author information
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Gilbert Karayakoupoglouj Department of Laboratory Medicine, Haykal Hospital, Tripoli, LebanonView further author information
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Malak Naboulsij Department of Laboratory Medicine, Haykal Hospital, Tripoli, LebanonView further author information
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Monzer Hamzek Department of Microbiology, Nini Hospital, Tripoli, LebanonView further author information
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Salam Samadl Department of Laboratory Medicine, Centre Hospitalier du Nord, Zgharta, LebanonView further author information
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Elie Khouryl Department of Laboratory Medicine, Centre Hospitalier du Nord, Zgharta, LebanonView further author information
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Ricardo Sarrafm Department of Laboratory Medicine, Monla Hospital, Tripoli, LebanonView further author information
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Marwan Osmann Department of Microbiology, El-Youssef Hospital Center, Halba, Lebanon;o Department of Public and Ecosystem Health, College of Veterinary Medicine, Cornell University, Ithaca, NY, USAORCID Iconhttps://orcid.org/0000-0002-6235-2760View further author information
ORCID Icon,
Elie Bou Raadn Department of Microbiology, El-Youssef Hospital Center, Halba, LebanonView further author information
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Hadi El Aminn Department of Microbiology, El-Youssef Hospital Center, Halba, LebanonView further author information
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Ibrahim Abadip Department of Laboratory Medicine, Al Rassoul Al Azam, Beirut, LebanonView further author information
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Hicham Abdoq Department of Laboratory Medicine, Dar El Shifa, Tripoli, LebanonView further author information
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Marwan Chedidr Department of Laboratory Medicine, New Mazloum Hospital, Tripoli, LebanonView further author information
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Fatima Chamseddines Department of Laboratory Medicine, Bahman Hospital, LebanonView further author information
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Angelique Barakatt Department of Laboratory Medicine, Bellevue Medical Center, Mansourieh, LebanonView further author information
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Mohammad Houmaniu Department of Laboratory Medicine, Labib Medical Center, Saida, LebanonView further author information
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Antoine Haddadv Department of Clinical Pathology and Blood Bank, Sacre Coeur Hospital, Lebanese University, Mount Lebanon, LebanonView further author information
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Georges Abdel Nourw Department of Laboratory Medicine, Notre Dame des Secours University Hospital Center, Jbeil, Mount Lebanon, LebanonView further author information
,
Jacques E. Mokhbatx Department of Internal Medicine, Division of Infectious Diseases, Lebanese American of Beirut Medical Center-Rizk Hospital, Achrafieh, Beirut, LebanonView further author information
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Ziad Daoudy Keserwan Medical Center, Jounieh, Mount Lebanon, Lebanon;z Department of Clinical Microbiology and Infection Prevention, College of Medicine, Central Michigan University and Michigan Health Clinic, Michigan, USA;aa Department of Laboratory Medicine, Saint Georges Hospital University Medical Center, Achrafieh, Saida, LebanonView further author information
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Mohamad El-Zaataribb Department of Laboratory Medicine, Hammoud Hospital University Medical Center, Saida, LebanonView further author information
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Elie Salem Sokhncc Department of Laboratory Medicine, Lebanese Hospital Geitaoui-University Medical Center (UMC), Achrafieh, Beirut, Lebanon;dd Department of Medical Laboratory Technology, Faculty of Health Sciences, Beirut Arab University, Beirut, LebanonView further author information
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Nada Ghosnee Epidemiological Surveillance Unit, Ministry of Public Health, Beirut, LebanonView further author information
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Walid Ammarff General Director, Lebanese Ministry of Public Health, Beirut, LebanonView further author information
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Randa Hamadehgg PHC Department, Lebanese Ministry of Public Health. Global Health Team of Experts (GHTE), LebanonView further author information
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Ghassan M. Matara Center for Infectious Diseases Research (CIDR) and WHO Collaborating Center for Reference and Research on Bacterial Pathogens, American University of Beirut, Beirut, Lebanon;e Department of Experimental Pathology, Immunology, and Microbiology, Faculty of Medicine, American University of Beirut, Beirut, LebanonView further author information
,
George F. Araja Center for Infectious Diseases Research (CIDR) and WHO Collaborating Center for Reference and Research on Bacterial Pathogens, American University of Beirut, Beirut, Lebanon;hh Department of Pathology and Laboratory Medicine, American University of Beirut Medical Center, Beirut, LebanonView further author information
&
Ghassan S. Dbaibo for the Lebanese Inter-Hospital Pneumococcal Surveillance Program investigators#a Center for Infectious Diseases Research (CIDR) and WHO Collaborating Center for Reference and Research on Bacterial Pathogens, American University of Beirut, Beirut, Lebanon;b Department of Pediatrics and Adolescent Medicine, American University of Beirut, Faculty of Medicine, Beirut, LebanonCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-5813-5878View further author information
ORCID Icon show all
Pages 1905-1921 | Received 18 Jun 2022, Accepted 31 Oct 2022, Published online: 17 Nov 2022

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