Management of pregnancy blood pressure increase in the emergency room: role of PlGF-based biochemical markers and relative economic impact

References

• Mammaro A , Carrara S , Cavaliere A , et al. Hypertensive disorders of pregnancy. J Prenat Med. 2009;3:1–5.
   PubMedGoogle Scholar
• Roberts JM , Druzin M , August PA , et al. Hypertension in pregnancy. Washington (DC): ACOG; 2013.
   Google Scholar
• Bramham K , Briley AL , Seed P , et al. Adverse maternal and perinatal outcomes in women with previous preeclampsia: a prospective study. Am J Obstet Gynecol. 2011;204:512.e1–512.e9.
   PubMed Web of Science ®Google Scholar
• Huppertz B. Placental origins of preeclampsia: challenging the current hypothesis. Hypertension 2008;51:970–975.
   PubMed Web of Science ®Google Scholar
• WHO. Maternal mortality. Geneva (Switzerland): WHO; 2016.
   Google Scholar
• Duley L. The global impact of pre-eclampsia and eclampsia. Semin Perinatol. 2009;33:130–137.
   PubMed Web of Science ®Google Scholar
• Herraiz I , Simón E , Gómez-Arriaga PI , et al. Angiogenesis-related biomarkers (sFlt-1/PLGF) in the prediction and diagnosis of placental dysfunction: an approach for clinical integration. IJMS. 2015;16:19009–19026.
   Web of Science ®Google Scholar
• Sibai BM , Stella CL. Diagnosis and management of atypical preeclampsia-eclampsia. Am J Obstet Gynecol. 2009;200:481.e1–481.e7.
   Web of Science ®Google Scholar
• Shennan AH , Redman C , Cooper C , et al. Are most maternal deaths from pre-eclampsia avoidable? Lancet 2012;379:1686–1687.
   PubMed Web of Science ®Google Scholar
• Rodriguez A , Tuuli MG , Odibo AO. First-, second-, and third-trimester screening for preeclampsia and intrauterine growth restriction. Clin Lab Med. 2016;36:331–351.
   PubMed Web of Science ®Google Scholar
• Henderson JT , Thompson JH , Burda BU , et al. Screening for preeclampsia: a systematic evidence review for the U.S. preventive services task force. Rockville (MD): Agency for Healthcare Research and Quality (US); 2017 (Report No.: 14-05211-EF-1).
   Google Scholar
• US Preventive Services Task Force, Bibbins-Domingo K , Grossman DC , et al. Screening for preeclampsia: US Preventive Services Task Force Recommendation Statement. JAMA. 2017;317:1661–1667.
   PubMed Web of Science ®Google Scholar
• Milne F , Redman C , Walker J , et al. Assessing the onset of pre-eclampsia in the hospital day unit: summary of the pre-eclampsia guideline (PRECOG II). BMJ. 2009;339:b3129.
   PubMed Web of Science ®Google Scholar
• Hund M , Verhagen-Kamerbeek W , Reim M , et al. Influence of the sFlt-1/PlGF ratio on clinical decision-making in women with suspected preeclampsia – the PreOS study protocol. Hypertens Pregnancy. 2015;34:102–115.
   PubMed Web of Science ®Google Scholar
• Acharya A , Brima W , Burugu S , et al. Prediction of preeclampsia-bench to bedside. Curr Hypertens Rep. 2014;16:491.
   PubMed Web of Science ®Google Scholar
• Meads CA , Cnossen JS , Meher S , et al. Methods of prediction and prevention of pre-eclampsia: systematic reviews of accuracy and effectiveness literature with economic modelling. Health Technol Assess (Rockv). 2008;12:iii–iiv.
   Web of Science ®Google Scholar
• Klein E , Schlembach D , Ramoni A , et al. Influence of the sFlt-1/PlGF ratio on clinical decision-making in women with suspected preeclampsia. Plos One. 2016;11:e0156013.
   PubMed Web of Science ®Google Scholar
• Verlohren S , Herraiz I , Lapaire O , et al. The sFlt-1/PlGF ratio in different types of hypertensive pregnancy disorders and its prognostic potential in preeclamptic patients. Am J Obstet Gynecol. 2012;206:58.e1–58.e8.
   PubMed Web of Science ®Google Scholar
• Perales A , Delgado JL , de la Calle M , et al. sFlt-1/PlGF for prediction of early-onset pre-eclampsia: STEPS (Study of Early Pre-eclampsia in Spain). Ultrasound Obstet Gynecol. 2017;50:373–382.
   PubMed Web of Science ®Google Scholar
• Redman CWG , Staff AC. Preeclampsia, biomarkers, syncytiotrophoblast stress, and placental capacity. Am J Obstet Gynecol. 2015;213(4):S9.e1–S9.e11.
   PubMed Web of Science ®Google Scholar
• Chappell LC , Duckworth S , Griffin M , et al. OS100. Plasma placental growth factor (PLGF) measurement in women presenting with suspected pre-eclampsia: the pelican study. Pregnancy Hypertens Int J Womens Cardiovasc Heal. 2012;2:233–234.
   PubMedGoogle Scholar
• Zeisler H , Llurba E , Chantraine F , et al. Predictive value of the sFlt-1:PlGF ratio in women with suspected preeclampsia. N Engl J Med. 2016;374:13–22.
   PubMed Web of Science ®Google Scholar
• National Institute for Health and Care Excellence. PlGF-based testing to help diagnose suspected pre-eclampsia (Triage PlGF test, Elecsys immunoassay sFlt-1/PlGF ratio, DELFIA Xpress PlGF 1-2-3 test, and BRAHMS sFlt-1 Kryptor/BRAHMS PlGF plus Kryptor PE ratio) [Internet]. London: National Institute for Health and Care Excellence; 2016 [cited May]. p. 1–6. Available from: https://www.nice.org.uk/guidance/dg23
   Google Scholar
• Gordijn SJ , Beune IM , Thilaganathan B , et al. Consensus definition of fetal growth restriction: a Delphi procedure. Ultrasound Obstet Gynecol. 2016;48:333–339.
   PubMed Web of Science ®Google Scholar
• North RA , McCowan LME , Dekker GA , et al. Clinical risk prediction for pre-eclampsia in nulliparous women: development of model in international prospective cohort. BMJ. 2011;342:d1875.
   PubMed Web of Science ®Google Scholar
• Poon LC , Kametas NA , Chelemen T , et al. Maternal risk factors for hypertensive disorders in pregnancy: a multivariate approach. J Hum Hypertens. 2010;24:104–110.
   PubMed Web of Science ®Google Scholar
• Roberge S , Nicolaides KH , Demers S , et al. Prevention of perinatal death and adverse perinatal outcome using low-dose aspirin: a meta-analysis. Ultrasound Obstet Gynecol. 2013;41:491–499.
   PubMed Web of Science ®Google Scholar
• NICE [internet]. London (UK): National Institute for Health and Care Excellence; c2010–2011. Hypertension in pregnancy: diagnosis and management NICE; 2011 January [cited 2017 Dec 19]. Available from: www.nice.org.uk/guidance/cg107.
   Google Scholar
• Bramham K , Parnell B , Nelson-Piercy C , et al. Chronic hypertension and pregnancy outcomes: systematic review and meta-analysis. BMJ. 2014;348:g2301.
   PubMed Web of Science ®Google Scholar
• Bujold E , Roberge S , Nicolaides KH. Low-dose aspirin for prevention of adverse outcomes related to abnormal placentation. Prenat Diagn. 2014;34:642–648.
   PubMed Web of Science ®Google Scholar
• Sibai B. Pre-Eclampsia Triage by Rapid Assay of Novel Biomarkers of Placental Function and Maternal Adaptation (PETRA). Confidential company submission. San Diego (CA): Alere, Inc.; 2014.
   Google Scholar
• Álvarez-Fernández I , Prieto B , Rodríguez V , et al. New biomarkers in diagnosis of early onset preeclampsia and imminent delivery prognosis. Clin Chem Lab Med. 2014;52:1159–1168.
   PubMed Web of Science ®Google Scholar
• Herraiz I, Llurba E, Verlohren S, et al., on behalf of the Spanish Group for the Study of Angiogenic Markers in Preeclampsia. Update on the diagnosis and prognosis of preeclampsia with the aid of the sFlt-1/ PlGF ratio in singleton Pregnancies. Fetal Diagn Ther. 2018;43:81–89.
   Google Scholar
• Frusca T , Gervasi MT , Paolini D , et al. Budget impact analysis of sFlt-1/PlGF ratio as prediction test in Italian women with suspected preeclampsia. J Matern Fetal Neonatal Med. 2017;30:2166–2173.
   PubMed Web of Science ®Google Scholar
• Duckworth S , Chappell LC , Seed PT , et al. Placental growth factor (PLGF) in women with suspected pre-eclampsia prior to 35 weeks’ gestation: a budget impact analysis. Plos One. 2016;11:e0164276.
   PubMed Web of Science ®Google Scholar
• Hadker N , Garg S , Costanzo C , et al. Financial impact of a novel pre-eclampsia diagnostic test versus standard practice: a decision-analytic modeling analysis from a UK healthcare payer perspective. J Med Econ. 2010;13:728–737.
   PubMedGoogle Scholar
• Hadker N , Garg S , Costanzo C , et al. Are there financial savings associated with supplementing current diagnostic practice for preeclampsia with a novel test? Learnings from a modeling analysis from a German payer perspective. Hypertens Pregn. 2013;32:105–119.
   PubMed Web of Science ®Google Scholar