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Education and Debate Article

Umbilical artery base deficit/excess: sailing blindly in a thick fog

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Pages 3990-3993 | Received 11 Jul 2019, Accepted 24 Oct 2019, Published online: 20 Nov 2019

References

  • American College of Obstetricians and Gynecologists’ Task Force on Neonatal Encephalopathy. Neonatal encephalopathy and neurologic outcome, second edition. Pediatrics. 2014;133(5):e1482–e1488.
  • Committee on Fetus and Newborn, Papile L-A, Baley JE, Benitz W, et al. Hypothermia and neonatal encephalopathy. Pediatrics. 2014;133(6):1146–1150.
  • Ross MG. Threshold of metabolic acidosis associated with newborn cerebral palsy: medical legal implications. Am J Obstet Gynecol. 2019;220(4):348–353.
  • MacLennan AH, Thompson SC, Gecz J. Cerebral palsy: causes, pathways, and the role of genetic variants. Am J Obstet Gynecol. 2015;213(6):779–788.
  • Martin L. All you really need to know to interpret arterial blood gases. J Am Chem Soc. 2000;190(5):642.
  • Olofsson P. Determination of base excess in umbilical cord blood at birth: accessory or excess? Am J Obstet Gynecol. 2015;213(3):259–261.
  • Knutzen L, Svirko E, Impey L. The significance of base deficit in acidemic term neonates. Am J Obstet Gynecol. 2015;213(3):373.e1–373.e7.
  • Mokarami P. Pitfalls in interpreting umbilical cord blood gases and lactate at birth. Annu Rev Med. 2013;57:403–417.
  • Daboval T, Ouellet P, MacLean G, et al. Is cord eucapnic pH a good marker of neurological compromise and death? Proceedings of the Paediatric Academy Society Meeting; 2018 May 6; Toronto (Canada): Paediatric Academy Society; 2018.
  • Mokarami P, Wiberg N, Olofsson P. An overlooked aspect on metabolic acidosis at birth: blood gas analyzers calculate base deficit differently. Acta Obstet Gynecol Scand. 2012;91(5):574–579.
  • Brandis K. The great trans-atlantic acid-base debate. In: Acid base physiology. University of California. p. 9.5.1–9.5.3. Available from: https://med.libretexts.org/link?10923 (Accessed November 14 2019).
  • Stewart PA. Modern quantitative acid–base chemistry. Can J Physiol Pharmacol. 1983;61(12):1444–1461.
  • Pomerance JJ. Section 2 blood gas components. In: JJ Pomerance, editor. Interpreting umbilical cord blood gases. 2nd ed. Glendora (CA): BNMG; 2012: p. 19–24.
  • CLSI. Blood gas and PH analysis and related measurements; approved guideline. CLSI document. 2nd ed. Vol. 29. Wayne (PA): Clinical and Laboratory Standards Institute; 2009.
  • Racinet C, Ouellet P, Charles F, et al. Neonatal metabolic acidosis at birth: in search of a reliable marker. Gynecol Obstet Fertil. 2016;44(6):357–362.
  • Kro GAB, Yli BM, Rasmussen S, et al. Association between umbilical cord artery pCO2 and the Apgar score; elevated levels of pCO2 may be beneficial for neonatal vitality after moderate acidemia. Acta Obstet Gynecol Scand. 2013;92(6):662–670.
  • Brackett NC, Cohen JJ, Schwartz WB. Carbon dioxide titration curve of normal man – effect of increasing degrees of acute hypercapnia on acid-based equilibrium. N Engl J Med. 1965;272(1):6–12.
  • Low JA, Lindsay BG, Derrick EJ. Threshold of metabolic acidosis associated with newborn complications. Am J Obstet Gynecol. 1997;177(6):1391–1394.
  • Hankins G, Speer M. Defining the pathogenesis and pathophysiology of neonatal encephalopathy and cerebral palsy. Obstet Gynecol. 2003;102(3):628–636.
  • Shankaran S, Laptook A, Wright LL, et al. Whole-body hypothermia for neonatal encephalopathy: animal observations as a basis for a randomized, controlled pilot study in term infants. Pediatrics. 2002;110(2):377–385.

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