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Natural Product Research
Formerly Natural Product Letters
Volume 30, 2016 - Issue 22
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Short Communications

Antileishmanial diterpenoid alkaloids from Aconitum spicatum (Bruhl) Stapf

Sajan L. ShyaulaFaculty of Science, Nepal Academy of Science and Technology, Lalitpur, NepalCorrespondence[email protected]
,
Tensangmu TamangDepartment of Chemistry, Tri-Chandra Multiple Campus, Tribhuvan University, Kathmandu, Nepal
,
Nida GhouriHEJ Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan
,
Achyut AdhikariHEJ Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan
,
Shanti MarasiniDepartment of Chemistry, Tri-Chandra Multiple Campus, Tribhuvan University, Kathmandu, Nepal
,
Gan B. BajracharyaFaculty of Science, Nepal Academy of Science and Technology, Lalitpur, Nepal
,
Mangala D. ManandharFaculty of Science, Nepal Academy of Science and Technology, Lalitpur, Nepal
&
Muhammad Iqbal ChoudharyHEJ Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan;Faculty of Science, Department of Biochemistry, King Abdulaziz University, Jeddah, Saudi Arabia
 show all
Pages 2590-2593 | Received 24 Jun 2015, Accepted 12 Sep 2015, Published online: 30 Nov 2015

References

  • Ameri A. 1998. The effects of Aconitum alkaloids on the central nervous system. Prog Neurobiol. 56:211–235.10.1016/S0301-0082(98)00037-9
  • Béziyin C, Tomasi S, Lohézic-Le Dévéhat F, Boustie J. 2003. Cytotoxic activity of some lichen extracts on murine and human cancer cell lines. Phytomedicine. 10:499–503.
  • Friese J, Gleitz J, Gutser UT, Heubach JF, Matthiesen T, Wilffert B, Selve N. 1997. Aconitum sp. alkaloids: the modulation of voltage-dependent Na+ channels, toxicity and antinociceptive properties. Eur J Pharmacol. 337:165–174.10.1016/S0014-2999(97)01268-5
  • Gao LM, Wei XM, Yang L. 2005. Two new norditerpenoid alkaloids from Aconitum spicatum Stapf. Chinese Chem Lett. 16:475–478.
  • Ghimire SK, Sapkota IB, Oli BR, Parajuli RR. 2008. Non-timber forest products of Nepal Himalaya. Kathmandu: WWF Nepal.
  • González P, Marín C, Rodríguez-González I, Hitos AB, Rosales MJ, Reina M, Díaz JG, González-Coloma A, Sánchez-Moreno M. 2005. In vitro activity of C20-diterpenoid alkaloid derivatives in promastigotes and intracellular amastigotes of Leishmania infantum. Int J Antimicrob Agents. 25:136–141.10.1016/j.ijantimicag.2004.08.010
  • Guo ZJ, Xu Y, Zhang H, Li MY, Xi K. 2014. New alkaloids from Aconitum taipaicum and their cytotoxic activities. Nat Prod Res. 28:164–168.10.1080/14786419.2013.861832
  • Mishra BB, Kale RR, Prasad V, Tiwari VK, Singh RK. 2011. Scope of natural products in fighting against leishmaniasis. In: Tiwari VK, Mishra BB, editors. Opportunity, challenge and scope of natural products in medicinal chemistry. Trivandrum, Kerala: Research Signpost; p. 121–154.
  • Peixoto JA, Andrade e Silva MLA, Crotti AEM, Cassio Sola Veneziani RCS, Gimenez VMM, Januário AH, Groppo M, Magalhães LG, Dos Santos FF, Albuquerque S, et al. 2011. Antileishmanial activity of the hydroalcoholic extract of Miconia langsdorffii, isolated compounds, and semi-synthetic derivatives. Molecules. 16:1825–1833.10.3390/molecules16021825
  • Singhuber J, Zhu M, Prinz S, Kopp B. 2009. Aconitum in traditional Chinese medicine – a valuable drug or an unpredictable risk? J Ethnopharmacol. 126:18–30.10.1016/j.jep.2009.07.031
  • WHO. 2010. Control of the leishmaniases. World Health Organization technical report series 949; [cited 2015 Apr]. Available from: http://whqlibdoc.who.int/trs/WHO_TRS_949_eng.pdf.
  • Yin TP, Cai L, Zhou H, Zhu XF, Chen Y, Ding ZT. 2014. A new C19-diterpenoid alkaloid from the roots of Aconitum duclouxii. Nat Prod Res. 28:1649–1654.10.1080/14786419.2014.927463
  • Yuan CL, Wang XL. 2012. Isolation of active substances and bioactivity of Aconitum sinomontanum Nakai. Nat Prod Res. 26:2099–2102.
  • Yunusov MS. 2011. Antiarrhythmic agents based on diterpenoid alkaloids. Russ Chem Bull. 60:633–638.10.1007/s11172-011-0098-7

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