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Natural Product Research
Formerly Natural Product Letters
Volume 30, 2016 - Issue 24
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Research Articles

Normal phase HPLC-based activity profiling of non-polar crude plant extracts – acetylcholinesterase inhibiting guttiferones from Montrouziera cauliflora as a case study

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Pages 2754-2759 | Received 24 Jun 2015, Accepted 16 Jan 2016, Published online: 26 Apr 2016

References

  • Awang K, Chan G, Litaudon M, Ismail NH, Martin M-T, Gueritte F. 2010. 4-Phenylcoumarins from Mesua elegans with acetylcholinesterase inhibitory activity. Bioorg Med Chem. 18:7873–7877. doi:10.1016/j.bmc.2010.09.044.
  • Belluti F, Bartolini M, Bottegoni G, Bisi A, Cavalli A, Andrisano V, Rampa A. 2011. Benzophenone-based derivatives: a novel series of potent and selective dual inhibitors of acetylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation. Eur J Med Chem. 46:1682–1693. doi:10.1016/j.ejmech.2011.02.019.
  • Bertrand S, Petit C, Marcourt L, Ho R, Gindro K, Monod M, Wolfender J-L. 2014. HPLC profiling with at-line microdilution assay for the early identification of antifungal compounds in plants from French Polynesia. Phytochem Anal. 25:106–112. doi:10.1002/pca.2473.
  • Costa Júnior JS, de Almeida AAC, Ferraz AdBF, Rossatto RR, Silva TG, Silva PBN, Militão GCG, Citó AMdGL, Santana LCLR, Carvalho FAdA, et al. 2013. Cytotoxic and leishmanicidal properties of garcinielliptone FC, a prenylated benzophenone from Platonia insignis. Nat Prod Res. 27:470–474. doi:10.1080/14786419.2012.695363.
  • Cummings JL. 2004. Alzheimer’s disease. N Engl J Med. 351:56–67. doi:10.1056/NEJMra040223.
  • Di Giovanni S, Borloz A, Urbain A, Marston A, Hostettmann K, Carrupt PA, Reist M. 2008. In vitro screening assays to identify natural or synthetic acetylcholinesterase inhibitors: thin layer chromatography versus microplate methods. Eur J Pharma Sci. 33:109–119. doi:10.1016/j.ejps.2007.10.004.
  • Ferchichi L, Derbré S, Mahmood K, Touré K, Guilet D, Litaudon M, Awang K, Hadi AHA, Le Ray AM, Richomme P. 2012. Bioguided fractionation and isolation of natural inhibitors of advanced glycation end-products (AGEs) from Calophyllum flavoramulum. Phytochemistry. 78:98–106. doi:10.1016/j.phytochem.2012.02.006.
  • Frank J, Chin XWD, Schrader C, Eckert GP, Rimbach G. 2012. Do tocotrienols have potential as neuroprotective dietary factors? Ageing Res Rev. 11:163–180. doi:10.1016/j.arr.2011.06.006.
  • Haute Autorité de Santé. 2012. Place des médicaments du traitement symptomatique de la maladie d’Alzheimer. FICHE BUM – MARS. Available from: http://www.has-sante.fr/portail/jcms/c_1231959/fr/place-des-medicaments-du-traitement-symptomatique-de-la-maladie-dalzheimer-fiche-bum-mars-1232012 ( consulted on 1231919/1231908/1232014).
  • Hay AE, Guilet D, Morel C, Larcher G, Macherel D, Le Ray AM, Litaudon M, Richomme P. 2003. Antifungal chromans inhibiting the mitochondrial respiratory chain of pea seeds and new xanthones from Calophyllum caledonicum. Planta Med. 69:1130–1135. doi:10.1055/s-2003-818004.
  • Hay AE, Merza J, Landreau A, Litaudon M, Pagniez F, Pape PL, Richomme P. 2008. Antileishmanial polyphenols from Garcinia vieillardii. Fitoterapia. 79:42–46. doi:10.1016/j.fitote.2007.07.005.
  • Iinuma M, Tosa H, Tanaka T, Asai F, Shimano R. 1995. Two new xanthones from the root bark of Garcinia subelliptica. Heterocycles. 40:279–284. doi:10.3987/com-94-s25.
  • Ito C, Mishina Y, Litaudon M, Cosson J-P, Furukawa H. 2000. Xanthone and dihydroisocoumarin from Montrouziera sphaeroidea. Phytochemistry. 53:1043–1046. doi:10.1016/S0031-9422(99)00442-2.
  • Jiang W-W, Su J, Wu X-D, He J, Peng L-Y, Cheng X, Zhao Q-S. 2015. Geissoschizine methyl ether N-oxide, a new alkaloid with antiacetylcholinesterase activity from Uncaria rhynchophylla. Nat Prod Res. 29:842–847. doi:10.1080/14786419.2014.989847.
  • Lenta BN, Vonthron-Sénécheau C, Weniger B, Devkota KP, Ngoupayo J, Kaiser M, Naz Q, Choudhary MI, Tsamo E, Sewald N. 2007. Leishmanicidal and cholinesterase inhibiting activities of phenolic compounds from Allanblackia monticola and Symphonia globulifera. Molecules. 12:1548–1557. doi:10.3390/12081548.
  • Marston A, Kissling J, Hostettmann K. 2002. A rapid TLC bioautographic method for the detection of acetylcholinesterase and butyrylcholinesterase inhibitors in plants. Phytochem Anal. 13:51–54. doi:10.1002/pca.623.
  • Masullo M, Bassarello C, Suzuki H, Pizza C, Piacente S. 2008. Polyisoprenylated benzophenones and an unusual polyisoprenylated tetracyclic xanthone from the fruits of Garcinia cambogia. J Agric Food Chem. 56:5205–5210. doi:10.1021/jf800416j.
  • Mouffok S, Haba H, Lavaud C, Long C, Benkhaled M. 2012. Chemical constituents of Centaurea omphalotricha Coss. & Durieu ex Batt. & Trab. Rec Nat Prod. 6:292–295.
  • Nguyen LH, Venkatraman G, Sim KY, Harrison LJ. 2005. Xanthones and benzophenones from Garcinia griffithii and Garcinia mangostana. Phytochemistry. 66:1718–1723. doi:10.1016/j.phytochem.2005.04.032.
  • Ohnmacht S, West R, Simionescu R, Atkinson J. 2008. Assignment of the 1H and 13C NMR of tocotrienols. Magn Reson Chem. 46:287–294. doi:10.1002/mrc.2176.
  • Potterat O, Hamburger M. 2014. Combined use of extract libraries and HPLC-based activity profiling for lead discovery: potential, challenges, and practical considerations. Planta Med. 80:1171–1181. doi:10.1055/s-0034-1382900.

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