Publication Cover
Natural Product Research
Formerly Natural Product Letters
Volume 32, 2018 - Issue 4
336
Views
19
CrossRef citations to date
0
Altmetric
Short Communication

Immune modulation properties of herbal plant leaves: Phyllanthus niruri aqueous extract on immune cells of tuberculosis patient - in vitro study

, , &
Pages 463-467 | Received 26 Sep 2016, Accepted 17 Mar 2017, Published online: 10 Apr 2017

References

  • Amin ZA, Abdulla MA, Ali HM, Alshawsh MA, Qadir SW. 2012a. Assessment of In vitro antioxidant, antibacterial and immune activation potentials of aqueous and ethanol extracts of Phyllanthus niruri. J Sci Food Agric. 92:1874–1877.10.1002/jsfa.5554
  • Amin ZA, Bilgen M, Alshawsh MA, Ali HM, Hadi AH, Abdulla MA. 2012. Protective role of Phyllanthus niruri extract against thioacetamide-induced liver cirrhosis in rat model. Evid Based Complement Alternat Med. 2012:241583.
  • Chatterjee M, Sil PC. 2006. Hepatoprotective effect of aqueous extract of Phyllanthus niruri on nimesulide-induced oxidative stress in vivo. Indian J Biochem Biophys. 43:299–305.
  • Colpo E, Vilanova CD, Pereira RP, Reetz LG, Oliveira L, Farias IL, Boligon AA, Athayde ML, Rocha JB. 2014. Antioxidant effects of Phyllanthus niruri tea on healthy subjects. Asian Pac J Trop Med. 7:113–118.10.1016/S1995-7645(14)60005-5
  • Giribabu N, Rao PV, Kumar KP, Muniandy S, Swapna Rekha S, Salleh N. 2014. Aqueous extract of Phyllanthus niruri leaves displays in vitro antioxidant activity and prevents the elevation of oxidative stress in the kidney of streptozotocin-induced diabetic male rats. Evid Based Complement Alternat Med. 2014:834815.
  • Huang ST, Pang JH, Yang RC. 2010. Anti-cancer effects of Phyllanthus urinaria and relevant mechanisms. Chang Gung Med J. 33:477–487.
  • Ibrahim D, Hong LS, Kuppan N. 2013. Antimicrobial activity of crude methanolic extract from Phyllanthus niruri. Nat Prod Commun. 8:493–496.
  • Jagetia GC, Baliga MS. 2004. The evaluation of nitric oxide scavenging activity of certain indian medicinal plants in vitro: a preliminary study. J Med Food. 7:343–348.10.1089/jmf.2004.7.343
  • Khan TA, Mazhar H, SalehaS, Tipu HN, Muhammad N& Abbas MN. 2016. Interferon-gamma improves macrophages function against M. tuberculosis in multidrug-resistant tuberculosis patients. Chemother Res Pract. 20: 7295390.
  • Liu S, Wei W, Li Y, Lin X, Shi K, Cao X, Zhou M. 2014. In vitro and in vivo anti-hepatitis B virus activities of the lignan nirtetralin B isolated from Phyllanthus niruri L. J Ethnopharmacol. 157:62–68.10.1016/j.jep.2014.09.019
  • Mellinger CG, Carbonero ER, Noleto GR, Cipriani TR, Oliveira MB, Gorin PA, Iacomini M. 2005. Chemical and biological properties of an arabinogalactan from Phyllanthus niruri. J Nat Prod. 68:1479–1483.10.1021/np050129s
  • Nworu CS, Akah PA, Okoye FB, Proksch P, Esimone CO. 2010. The effects of Phyllanthus niruri aqueous extract on the activation of murine lymphocytes and bone marrow-derived macrophages. Immunol Invest. 39:245–267.10.3109/08820131003599585
  • O'Garra A, Redford PS, McNab FW, Bloom CI, Wilkinson RJ & Berry MP. 2013. The immune response in tuberculosis. Annu Rev Immunol. 31:475–527.10.1146/annurev-immunol-032712-095939
  • Paur I, Carlsen MH, Halvorsen BL & Blomhoff R. 2011. Antioxidants in herbs and spices: roles in oxidative stress and redox signaling. In: Benzie IFF & Wachtel-Galor S , editors. Herbal medicine: biomolecular and clinical aspects. 2nd ed. Boca Raton (FL): CRC Press/Taylor and Francis.
  • Sarkar MK, Sil PC. 2007. Hepatocytes are protected by herb Phyllanthus niruri protein isolate against thioacetamide toxicity. Pathophysiology. 14:113–120.10.1016/j.pathophys.2007.08.001
  • Sharma P, Parmar J, Verma P, Sharma P, Goyal PK. 2009. Anti-tumor activity of Phyllanthus niruri (a medicinal plant) on chemical-induced skin carcinogenesis in mice. Asian Pac J Cancer Prev. 10:1089–1094.
  • Tjandrawinata RR, Dirjomuljono M. 2011. Clinical trials involving phyllanthus species. In: Kuttan R, Harikumar KB, editors. Phyllanthus species: scientific evaluation and medicinal applications. Boca Raton: CRC Press; p. 289–313.
  • Urdahl KB, Shafiani S, Ernst JD. 2011. Initiation and regulation of T-cell responses in tuberculosis. Mucosal Immunol. 4:288–293.10.1038/mi.2011.10
  • Xu M, Zhu HT, Cheng RR, Wang D, Yang CR, Tanaka T, Kouno I, Zhang YJ. 2016. Antioxidant and hyaluronidase inhibitory activities of diverse phenolics in Phyllanthus emblica. Nat Prod Res. 30 (23):2726–2729.10.1080/14786419.2015.1137573
  • Yan H, Han LR, Zhang X, Feng JT. 2017. Two new Anti-TMV active chalconoid analogues from the root of Phyllanthus emblica. Nat Prod Res. Jan 23:1–6. doi:10.1080/14786419.2017.1280487.
  • Yang CS, Yuk JM, Jo EK. 2009. The role of nitric oxide in mycobacterial infections. Immune Netw. 9:46–52.10.4110/in.2009.9.2.46

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.