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Natural Product Research
Formerly Natural Product Letters
Volume 32, 2018 - Issue 10
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Research Articles

New natural product -an efficient antimicrobial applications of new newly synthesized pyrimidine derivatives by the electrochemical oxidation of hydroxyl phenol in the presence of 2-mercapto-6-(trifluoromethyl) pyrimidine-4-ol as nucleophile

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Pages 1161-1169 | Received 10 Mar 2017, Accepted 25 Apr 2017, Published online: 11 May 2017

References

  • Abu-Hashem AA, Youssef MM, Hussein HAR. 2011. Design, synthesis of novel thiourea and pyrimidine derivatives as potential antitumor agents. J Chin Chem Soc. 58:41–48.10.1002/jccs.201190056
  • Azzem MA, Zahran M, Hagagg E. 1994. Electrooxidation of catechol in the presence of 1,3-dimethylbarbituric acid at graphite anode and nickel hydroxide electrode. Bull Chem Soc Jpn. 67:1390–1393.10.1246/bcsj.67.1390
  • Boakye YK, Fiagbe N, Ayim J. 1977. Antimicrobial properties of some West African medicinal plants. J Nat Prod. 40:543–545.
  • Bounamama H, Noel T, Villard J, Benharref A, Jana M. 2005. Antimicrobial activities of the leaf extracts of two Moroccan Cistus L. species. J Ethno Pharmacol. 104:104–107.
  • Brunton LL, Lazo JS, Parker KL, Goodman LS, Gilman A. 2005. Goodman and Gilman’s the pharmacological basis of therapeutics. New York, NY: McGraw-Hill.
  • Chandrashekaran S, Nagarajan S. 2005. Microwave-assisted synthesis and anti-bacterial activity of some 2-amino-6-aryl-4-(2-thienyl)pyrimidines IL Farmaco. 60:279–282.
  • Determination of minimum inhibitory concentrations (MICs) of antibacterial agents by broth dilution. 2003. Clin Microbiol Infect Clin Microbiol Infect. 9:1–7.
  • Falcão EPdS, de Melo SJ, Srivastava RM, Catanho MTJdA, Nascimento SCD. 2006. Synthesis and antiinflammatory activity of 4-amino-2-aryl-5-cyano-6-{3- and 4-(N-phthalimidophenyl)} pyrimidines. Eur J Med Chem. 41:276–282.10.1016/j.ejmech.2005.09.009
  • Gupta AK, Kayath HP, Sanjay, Singh A, Sharma G, Mishra KC. 1994. Anticonvulsant activity of pyrimidine thiols. Indian J Pharmacol. 26:227–228.
  • Gutmann F, Johnson C, Keyzer H, Molnar J. 1997. Charge-transfer complexes in biological systems. New York, NY: Marcel Dekker.
  • Hadacek F, Greger H. 2000. Phytochemical analysis and hemodynamic actions of Artemisia vulgaris L. Phytochemcal Anal. 11:137–147.10.1002/(ISSN)1099-1565
  • Ingaral N, Saravanan G, Amutha P, Nagarajan S. 2007. Synthesis, in vitro antibacterial and antifungal evaluations of 2amino-4-(1-naphthyl)-6-arylpyrimidines. Eur J Med Chem. 42:517–520.10.1016/j.ejmech.2006.09.012
  • Juby PF, Hudyma TW, Brown M, Essery JM, Partyka RA. 1979. Anti-allergy agents. 1.1, 6-dihydro-6-oxo-2- phenylpyrimidine-5-carboxylic acids and esters. J Med Chem. 22:263–269.10.1021/jm00189a009
  • Katritzky AR, Xu YJ, Tu H. 2003. Regiospecific synthesis of 3-substituted imidazo[1,2-a] pyridines, imidazo [1,2 a] pyrimidines, and imidazo [1,2-c] pyrimidine. J Org Chem. 68:4935–4937.10.1021/jo026797p
  • Khan ZUH, Chen Y, Khan S, Kong D, Liang MH, Wan P. 2014. Electrochemical initiation of nucleophilic substitution of hydroquinone with 4, 6-dimethylpyrimidine-2-thiol. Int J Electrochem Sci. 9:4665–4674.
  • Khan ZUH, Khan AU, Wan P, Chen Y, Khan D, Khan S, Tahir K. 2014. In vitro pharmacological screening of three newly synthesised pyrimidine derivatives. Nat Prod Res. 29:933–938.
  • Khan ZUH, Khan AU, Chen Y, Khan S, Kong D, Tahir K, Khan FU, Wan P, Jin X. 2015. Electrochemical oxidation of catechols in the presence of 4-mercapto-benzoic acid, to synthesis sulfanyl compounds and their biological studies. Tetrahedron. 71:1674–1678.10.1016/j.tet.2015.01.057
  • Koroch AR, Juliani HR, Zygadlo JA. 2007. Bioactivity of essential oils and their components. In Berger RG, editor. Flavours and fragrances chemistry, bioprocessing and sustainability. Heidelberg: Springer-Verlag; p. 87–115.
  • Lee HW, Bok YK, Joong BA. 2005. Molecular design, synthesis, and hypoglycemic and hypo lipidemic activities of novel pyrimidine derivatives having thiazolidinedione. Eur J Med Chem. 40:862–874.10.1016/j.ejmech.2005.03.019
  • Navgeet K, Aggarwal AK, Sharma N, Choudhary B. 2012. Synthesis and in vitro antimicrobial activity of pyrimidine derivatives. Int J Pharma Sci Drug Res. 4:199–204.
  • Nematollahi D, Rafiee M. 2004. Electrochemical oxidation of catechols in the presence of acetylacetone. J Electroanal Chem. 566:31–37.10.1016/j.jelechem.2003.10.044
  • Nourmohammadi F, Golabi SM, Saadnia A. 2002. Electrochemical synthesis of organic compounds: 1. Addition of sulfinic acids to electrochemically generated o- and p-benzoquinones. J Electro anal Chem. 529:12–19.10.1016/S0022-0728(02)00906-3
  • Okemo PO, Bais HP, Vivanco JM. 2003. In vitro activities of Maesa lanceolata extracts against fungal plant pathogens. Fitoterapia. 74:312–316.10.1016/S0367-326X(03)00039-X
  • Patel HR. 2014. Studies and synthesis of nitrogen, sulphur containing heterocycles and their biological evaluation [Research gate]. Thesis.
  • Pontikis R, Benhida R, Aubertin AH, Grieson DS, Monneret C. 2011. Anticancer agents. Eur J Med Chem. 46:5817–5824.
  • Rahaman SA, Pasad YR, Kumar P, Kumar B. 2009. Synthesis and anti-histaminic activity of some novel pyrimidines. Saudi Pharma J. 17:255–258.
  • Silverstein RM, Webster FM. 1998. Spectrometric identification organic compounds. 6th ed. New York, NY: Wiley; p. 217–249.
  • Smith PAS, Kan RO. 1964. Cyclization of iso thio cyanates as a route to phthalic and homophthalic acid derivatives. J Org Chem. 29:2261–2265.10.1021/jo01031a037
  • Vega S, Alonso J, Diaz JA, Jonquiere F. 1990. Synthesis of 3-substituted-4-phenyl-2-thioxo-1,2,3,4,5,6,7,8octahydrobenzo[4,5] thieno [2,3-d]pyrimidines. J Pharma Res. 7:491–495.
  • Zampini IC, Cuello S, Alberto MR, Ordoñez RM, Almeida RD, Solorzano E, Isla MI. 2009. Antimicrobial activity of selected plant species from the Argentine Puna against sensitive and multi-resistant bacteria. J Ethno Pharmacol. 124:499–505.10.1016/j.jep.2009.05.011

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