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Natural Product Research
Formerly Natural Product Letters
Volume 32, 2018 - Issue 22
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Short Communication

Naphthoquinone rich Onosma visianii Clem (Boraginaceae) root extracts induce apoptosis and cell cycle arrest in HCT-116 and MDA-MB-231 cancer cell lines

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Pages 2712-2716 | Received 11 Jun 2017, Accepted 20 Aug 2017, Published online: 07 Sep 2017

References

  • Al-Ejeh F, Kumar R, Wiegmans A, Lakhani SR, Brown MP, Khanna KK. 2010. Harnessing the complexity of DNA-damage response pathways to improve cancer treatment outcomes. Oncogene. 29:6085–6098.10.1038/onc.2010.407
  • Cadirci E, Suleyman H, Aksoy H, Halici Z, Ozgen U, Koc A, Ozturk N. 2007. Effects of Onosma armeniacum root extract on ethanol-induced oxidative stress in stomach tissue of rats. Chem Biol Interact. 170:40–48.10.1016/j.cbi.2007.06.040
  • Clifford B, Beljin M, Stark GR, Taylor WR. 2003. G2 arrest in response to topoisomerase II inhibitors: the role of p531. Cancer Res. 63:4074–4081.
  • Davis PH. 1988. Flora of Turkey and the East Aegean Islands. vol 6. Edinburgh: Edinburgh University Press.
  • Graikou K, Baranek KS, Pietrosiuk A, Damianakos H, Jeziorek M, Chinou I. 2011. Chemical analysis of Lithospermum canescens (Michx.) Lehm. Hairy roots through TLC, CC, GC-MS, ESI-MS, and NMR methods. Acta Chromatogr. 23:353–363.10.1556/AChrom.23.2011.2.12
  • Hu Y, Jiang Z, Leung KS, Zhao Z. 2006. Simultaneous determination of naphthoquinone derivatives in Boraginaceous herbs by high-performance liquid chromatography. Anal Chim Acta. 577:26–31.10.1016/j.aca.2006.06.031
  • Huang X, Traganos F, Darzynkiewicz Z. 2003. DNA damage induced by DNA topoisomerase I- and topoisomerase II-inhibitors detected by histone H2AX phosphorylation in relation to the cell cycle phase and apoptosis. Cell Cycle. 2:614–619.
  • Ito Y, Onobori K, Yamazaki T, Kawamura Y. 2011. Tigloylshikonin, a new minor Shikonin derivative, from the roots and the commercial root extract of lithospermum erythrorhizon. Chem Pharm Bull. 59:117–119.10.1248/cpb.59.117
  • Kastan MB, Bartek J. 2004. Cell cycle checkpoints and cancer. Nature. 432:316–323.10.1038/nature03097
  • Kretschmer N, Rinner B, Deutsch AJ, Lohberger B, Knausz H, Kunert O, Blunder M, Boechzelt H, Schaider H, Bauer R. 2012. Naphthoquinones from Onosma paniculata induce cell-cycle arrest and apoptosis in melanoma cells. J Nat Prod. 75:865–869.10.1021/np2006499
  • Naz S, Ahmad S, Ajaz Rasool S, Asad Sayeed S, Siddiqi R. 2006. Antibacterial activity directed isolation of compounds from Onosma hispidum. Microbiol Res. 161:43–48.10.1016/j.micres.2005.05.001
  • Nikita G, Vivek P, Chhaya G. 2015. Wound-healing activity of an oligomer of alkannin/shikonin, isolated from root bark of Onosma echioides. Nat Prod Res. 29:1584–1588.10.1080/14786419.2014.986126
  • Ozgen U, Coskun M, Kazaz C, Secen H. 2004. Naphthoquinones from the roots of Onosma argentatum Hub.-Mor. (Boraginaceae). Turk J Chem. 28:451–454.
  • Ozgen U, Ikbal M, Hacimuftuoglu A, Houghton PJ, Gocer F, Dogan H, Coskun M. 2006. Fibroblast growth stimulation by extracts and compounds of Onosma argentatum roots. J Ethnopharmacol. 104:100–103.10.1016/j.jep.2005.08.052
  • Papageorgiou VP, Assimopoulou AN, Couladouros EA, Hepworth D, Nicolaou KC. 1999. The chemistry and biology of alkannin, shikonin, and related naphthazarin natural products. Angew Chem Int Edit. 38:270–301.10.1002/(ISSN)1521-3773
  • Sezik E, Yeşİlada E, Tabata M, Honda G, Takaishi Y, Fujita T, Tanaka T, Takeda Y. 1997. Traditional medicine in Turkey VIII. Folk medicine in east anatolia; Erzurum, Erzincan, Agri, Kars. Igdir provinces Econ Bot. 51:195–211.10.1007/BF02862090
  • Taylor WR, Stark GR. 2001. Regulation of the G2/M transition by p53. Oncogene. 20:1803–1815.10.1038/sj.onc.1204252
  • Vukic MD, Vukovic NL, Djelic GT, Popovic SL, Zaric MM, Baskic DD, Krstic GB, Tesevic VV, Kacaniova MM. 2017. Antibacterial and cytotoxic activities of naphthoquinone pigments from Onosma visianii Clem. Excli J. 16:73–88.

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