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Natural Product Research
Formerly Natural Product Letters
Volume 32, 2018 - Issue 24
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Short Communication

The antidepressant-like activity of ellagic acid and its effect on hippocampal brain derived neurotrophic factor levels in mouse depression models

Hatice Asli BedelFaculty of Medicine, Department of Pharmacology, Akdeniz University, Antalya, Turkey
,
Ceren Kencebay ManasFaculty of Medicine, Department of Biophysics, Akdeniz University, Antalya, Turkey
,
Gül ÖzbeyFaculty of Medicine, Department of Pharmacology, Akdeniz University, Antalya, Turkey
&
Coşkun UstaFaculty of Medicine, Department of Pharmacology, Akdeniz University, Antalya, TurkeyCorrespondence[email protected]
Pages 2932-2935 | Received 14 Aug 2017, Accepted 10 Sep 2017, Published online: 11 Oct 2017

References

  • Barde YA, Edgar D, Thoenen H. 1982. Purification of a new neurotrophic factor from mammalian brain. EMBO J. 1:549–553.
  • Corbett S, Daniel J, Drayton R, Field M, Steinhardt R, Garrett N. 2010. Evaluation of the anti-inflammatory effects of ellagic acid. J Perianesth Nurs. 25:214–220.10.1016/j.jopan.2010.05.011
  • Dhingra D, Chhillar R. 2012. Antidepressant-like activity of ellagic acid in unstressed and acute immobilization-induced stressed mice. Pharmacol Rep. 64:796–807.10.1016/S1734-1140(12)70875-7
  • Duman RS, Monteggia LM. 2006. A neurotrophic model for stress-related mood disorders. Biol Psychiatry. 59:1116–1127.10.1016/j.biopsych.2006.02.013
  • Feng Y, Yang SG, Du XT, Zhang X, Sun XX, Zhao M, Sun GY, Liu RT. 2009. Ellagic acid promotes Abeta42 fibrillization and inhibits Abeta42-induced neurotoxicity. Biochem Biophys Res Commun. 390:1250–1254.10.1016/j.bbrc.2009.10.130
  • Girish C, Raj V, Arya J, Balakrishnan S. 2012. Evidence for the involvement of the monoaminergic system, but not the opioid system in the antidepressant-like activity of ellagic acid in mice. Eur J Pharmacol. 682:118–125.10.1016/j.ejphar.2012.02.034
  • Levi-Montalcini R. 1966. The nerve growth factor: its mode of action on sensory and sympathetic nerve cells. Harvey Lect. 60:217–259.
  • Nagahara AH, Tuszynski MH. 2011. Potential therapeutic uses of BDNF in neurological and psychiatric disorders. Nat Rev Drug Discov. 10:209–219.10.1038/nrd3366
  • Nakazawa T, Yasuda T, Ueda J, Ohsawa K. 2003. Antidepressant-like effects of apigenin and 2,4,5-trimethoxycinnamic Acid from Perilla frutescens in the forced swimming test. Biol Pharm Bull. 26:474–480.10.1248/bpb.26.474
  • Nibuya M, Morinobu S, Duman RS. 1995. Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments. J Neurosci. 15:7539–7547.
  • Nibuya M, Nestler EJ, Duman RS. 1996. Chronic antidepressant administration increases the expression of cAMP response element binding protein (CREB) in rat hippocampus. J Neurosci. 16:2365–2372.
  • Olgar Y, Ozturk N, Usta C, Puddu PE, Ozdemir S. 2014. Ellagic acid reduces L-type Ca2+ current and contractility through modulation of NO-GC-cGMP pathways in rat ventricular myocytes. J Cardiovasc Pharmacol. 64:567–573.10.1097/FJC.0000000000000153
  • Posser T, Kaster MP, Baraúna SC, Rocha JB, Rodrigues AL, Leal RB. 2009. Antidepressant-like effect of the organoselenium compound ebselen in mice: Evidence for the involvement of the monoaminergic system. Eur J Pharmacol. 602:85–91.10.1016/j.ejphar.2008.10.055
  • Quideau S, Feldman KS. 1996. Ellagitannin chemistry. Chem Rev. 96:475–504.10.1021/cr940716a
  • Usta C, Ozdemir S, Schiariti M, Puddu PE. 2013. The pharmacological use of ellagic acid-rich pomegranate fruit. Int J Food Sci Nutr. 64:907–913.10.3109/09637486.2013.798268
  • Uzar E, Alp H, Cevik MU, Firat U, Evliyaoglu O, Tufek A, Altun Y. 2012. Ellagic acid attenuates oxidative stress on brain and sciatic nerve and improves histopathology of brain in streptozotocin-induced diabetic rats. Neurol Sci. 33:567–574.10.1007/s10072-011-0775-1
  • Yilmaz B, Usta C. 2013. Ellagic acid-induced endothelium-dependent and endothelium-independent vasorelaxation in rat thoracic aortic rings and the underlying mechanism. Phytother Res. 27:285–289.10.1002/ptr.v27.2
  • Zuccato C, Cattaneo E. 2009. Brain-derived neurotrophic factor in neurodegenerative diseases. Nat Rev Neurol. 5:311–322.10.1038/nrneurol.2009.54

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