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Natural Product Research
Formerly Natural Product Letters
Volume 33, 2019 - Issue 2
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Research Articles

A new actinomycin Z analogue with an additional oxygen bridge between chromophore and β-depsipentapeptide from Streptomyces sp. KIB-H714

Miao DongState Key Laboratory of Phytochemistry and Plant Resources in West China, and Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, P.R. China;Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, P.R. China
,
Pei CaoState Key Laboratory of Phytochemistry and Plant Resources in West China, and Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, P.R. ChinaCorrespondence[email protected]
,
Ya-Tuan MaState Key Laboratory of Phytochemistry and Plant Resources in West China, and Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, P.R. China
,
Jianying LuoState Key Laboratory of Phytochemistry and Plant Resources in West China, and Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, P.R. China
,
Yijun YanState Key Laboratory of Phytochemistry and Plant Resources in West China, and Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, P.R. China
,
Rong-Tao LiFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, P.R. China
&
Sheng-Xiong HuangState Key Laboratory of Phytochemistry and Plant Resources in West China, and Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, P.R. ChinaCorrespondence[email protected]
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Pages 219-225 | Received 03 Jan 2018, Accepted 14 Feb 2018, Published online: 02 Mar 2018

References

  • Bitzer J, Gesheva V, Zeeck A. 2006. Actinomycins with altered threonine units in the β-peptidolactone. J Nat Prod. 69:1153–1157.10.1021/np060063g
  • Bitzer J, Streibel M, Langer HJ, Grond S. 2009. First Y-type actinomycins from Streptomyces with divergent structure-activity relationships for antibacterial and cytotoxic properties. Org Biomol Chem. 7:444–450.10.1039/B815689A
  • Cai W, Wang X, Elshahawi SI, Ponomareva LV, Liu X, McErlean MR, Cui Z, Arlinghaus AL, Thorson JS, Van Lanen SG. 2016. Antibacterial and cytotoxic actinomycins Y6-Y9 from Streptomyces sp. strain Gö-GS12. J Nat Prod. 79:2731–2739.10.1021/acs.jnatprod.6b00742
  • Chu W, Shinomiya M, Kamitori KY, Kamitori S, Carlson RG, Weaver RF, Takusagawa F. 1994. Role of D-valine residues in the antitumor drug actinomycin D: replacement of D-valines with other D-amino acids changes the DNA binding characteristics and transcription inhibitory activities. J Am Chem Soc. 116:7971–7982.10.1021/ja00097a003
  • Demain AL, Sanchez S. 2009. Microbial drug discovery: 80 years of progress. J Antibiot. 62:5–16.10.1038/ja.2008.16
  • Kamitori S, Takusagawa F. 1994. Multiple binding modes of anti-cancer drug actinomycin D: X-ray, molecular modeling and spectroscopic studies of d (GAAGCTTC)2-actinomycin D complexes and its host DNA. J Am Chem Soc. 116:4154–4165.10.1021/ja00089a002
  • Lackner H. 1975. Three-dimensional structure of the actinomycins. Angew Chem Int Ed. 14:375–386.10.1002/(ISSN)1521-3773
  • Lackner H, Bahner I, Shigematsu N, Pannell LK, Mauger AB. 2000. Structures of five components of the actinomycin Z complex from Streptomyces fradiae, two of which contain 4-chlorothreonine. J Nat Prod. 63:352–356.10.1021/np990416u
  • Schäfer M, Sheldrick GM, Bahner I, Lackner H. 1998. Crystal structures of actinomycin D and actinomycin Z3. Angew Chem Int Ed. 37:2381–2384.10.1002/(ISSN)1521-3773
  • Sobell HM. 1973. The stereochemistry of actinomycin binding to DNA and its implications in molecular biology. Progr Nucleic Acid Res Mol Biol. 13:153–190.10.1016/S0079-6603(08)60103-8
  • Van Lanen SG, Shen B. 2006. Microbial genomics for the improvement of natural product discovery. Curr Opin Microbiol. 9:252–260.10.1016/j.mib.2006.04.002
  • Versiani MA, Diyabalanage T, Ratnayake R, Henrich CJ, Bates SE, McMahon JB, Gustafson KR. 2011. Flavonoids from eight tropical plant species that inhibit the multidrug resistance transporter ABCG2. J Nat Prod. 74:262–266.10.1021/np100797y
  • Wilkinson B, Micklefield J. 2007. Mining and engineering natural-product biosynthetic pathways. Nat Chem Biol. 3:379–386.10.1038/nchembio.2007.7
  • Wu XD, He J, Li XY, Dong LB, Gong X, Gao X, Song LD, Li Y, Peng LY, Zhao QS. 2013. Triterpenoids and steroids with cytotoxic activity from Emmenopterys henryi. Planta Med. 79:1356–1361.

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