Advanced search
Publication Cover
Natural Product Research
Formerly Natural Product Letters
Volume 33, 2019 - Issue 21
Submit an article Journal homepage
282
Views
2
CrossRef citations to date
0
Altmetric
Research Articles

Microbial transformation of the anti-aging agent cycloastragenol by Mucor racemosus

Haijun LinSchool of Pharmacy, Nantong University, Nantong226001, PR China;
,
Baocheng JiangSchool of Pharmacy, Nantong University, Nantong226001, PR China;
,
Chen ChenSchool of Pharmacy, Nantong University, Nantong226001, PR China;
,
Yan SongSchool of Pharmacy, Nantong University, Nantong226001, PR China;
,
Min YangSchool of Pharmacy, Nantong University, Nantong226001, PR China;
,
Huilian HuangKey Laboratory of Modern Preparation of TCM, Jiangxi University of Traditional Chinese Medicine, ministry of education, Nanchang330004, PR China
&
Guangtong ChenSchool of Pharmacy, Nantong University, Nantong226001, PR China; Correspondence[email protected]
 show all
Pages 3103-3108 | Received 09 Jul 2018, Accepted 02 Sep 2018, Published online: 17 Nov 2018

References

  • Chen GT, Li J, Yan SS, Lin HJ, Wu JJ, Zhai XG, Song Y, Li JL. 2017. Biotransformation of 20(R)-panaxatriol by Mucor racemosus and the anti-hepatic fibrosis activity of some products. Nat. Prod. Res. 31(6):1880–1885.
  • Debeleç-Bütüner B, Öztürk MB, Tağ Ö, Akgün IH, Yetik-Anacak G, Bedir E, Korkmaz KS. 2018. Cycloartane-type sapogenol derivatives inhibit NFκB activation as chemopreventive strategy for inflammation-induced prostate carcinogenesis. Steroids, 135:9–20.
  • Fauce SR, Jamieson BD, Chin AC, Mitsuyasu RT, Parish ST, Ng HL, Kitchen CM, Yang OO, Harley CB, Effros RB. 2008. Telomerase-based pharmacologic enhancement of antiviral function of human CD8+ T lymphocytes. J. Immunol. 181:7400–7406.
  • Feng LM, Ji S, Qiao X, Li ZW, Lin XH, Ye M. 2015. Biocatalysis of cycloastragenol by Syncephalastrum racemosum and Alternaria alternate to discover anti-aging derivatives. Adv. Synth. Catal. 357:1928–1940.
  • Harley CB, Liu WM, Blasco M, Vera E, Andrews WH, Briggs LA, Raffaele JM. 2011. A natural product telomerase activator as part of a health maintenance program. Rejuv. Res. 14:45–56.
  • Kuban M, Ongen G, Bedir E. 2010. Biotransformation of cycloastragenol by Cunninghamella blakesleeana NRRL 1369 resulting a novel framework. Org. Lett. 12(19):4252–4255.
  • Kuban M, Ongen G, Khan IA, Bedir E. 2013. Microbial transformation of cycloastragenol. Phytochemistry. 88:99–104.
  • Lee SY, Chang WL, Li ZX, Kirkby NS, Tsai WC, Huang SF, Ou CH, Chang TC. 2018. Astragaloside VI and cycloastragenol-6-O-beta-D-glucoside promote wound healing in vitro and in vivo. Phytomedicine. 38:183–191.
  • Liu J, Zhao ZZ, Chen HB. 2011. Review of Astragali radix. Chin. Herb. Med. 3:90–105.
  • Ren S, Zhang H, Mu Y, Sun M, Liu P. 2013. Pharmacological effects of Astragaloside IV: a literature review. J. Tradit. Chin. Med. 33:413–416.
  • Wang C, Li Y, Yang X, Bi S, Zhang Y, Han D, Zhang D. 2017. Tetramethylpyrazine and astragaloside IV synergistically ameliorate left ventricular remodeling and preserve cardiac function in a rat myocardial infarction model. J. Cardiovasc. Pharmacol. 69:34–40.
  • Yang ZW, Ye M, Huang FX, He WN, Guo DA. 2012. Biocatalysis of cycloastragenol by filamentous fungi to produce unexpected triterpenes. Adv. Synth. Catal. 354:527–539.
  • Zhang CX, Ma WJ, Liu DL, Jia XJ, Zhao YM. 2018. Biotransformation of ursolic acid by Alternaria longipes AS 3.2875. Nat. Prod. Res. 32(5):536–543.
  • Zhang N, Wang XH, Mao SL, Zhao F. 2011. Astragaloside IV improves metabolic syndrome and endothelium dysfunction in fructose-fed rats. Molecules. 16:3896–3907.
  • Zhou RN, Song YL, Ruan JQ, Wang YT, Yan R. 2012. Pharmacokinetic evidence on the contribution of intestinal bacterial conversion to beneficial effects of astragaloside IV, a marker compound of Astragali radix, in traditional oral use of the herb. Drug Metab. Pharmacokinet. 27:586–597.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.