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Natural Product Research
Formerly Natural Product Letters
Volume 34, 2020 - Issue 11
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Short Communication

Gypensapogenin H from hydrolyzate of total Gynostemma pentaphyllum saponins induces apoptosis in human breast carcinoma cells

Xiaoshu ZhangSchool of Functional Food and Wine, Shenyang Pharmaceutical University, Shenyang, People’s Republic of China; ;Key Laboratory of Structure-Based Drug Design and Discovery, Shenyang Pharmaceutical University, Ministry of Education, Shenyang, People’s Republic of China; View further author information
,
Guohui ShiSchool of Functional Food and Wine, Shenyang Pharmaceutical University, Shenyang, People’s Republic of China; ;Key Laboratory of Structure-Based Drug Design and Discovery, Shenyang Pharmaceutical University, Ministry of Education, Shenyang, People’s Republic of China; View further author information
,
Xiaojun WuKey Laboratory of Structure-Based Drug Design and Discovery, Shenyang Pharmaceutical University, Ministry of Education, Shenyang, People’s Republic of China; ;Shenyang Pharmaceutical University, Shenyang, People’s Republic of ChinaView further author information
&
Yuqing ZhaoSchool of Functional Food and Wine, Shenyang Pharmaceutical University, Shenyang, People’s Republic of China; ;Key Laboratory of Structure-Based Drug Design and Discovery, Shenyang Pharmaceutical University, Ministry of Education, Shenyang, People’s Republic of China; Correspondence[email protected]
View further author information
Pages 1642-1646 | Received 25 Apr 2018, Accepted 11 Sep 2018, Published online: 23 Nov 2018

References

  • Bi X, Xia X, Mou T, Jiang B, Fan D, Wang P, Liu Y, Hou Y, Zhao Y. 2014. Anti-tumor activity of three ginsenoside derivatives in lung cancer is associated with Wnt/β-catenin signaling inhibition. Euro J Pharmacol. 742:145–152.
  • Cragg GM, Grothaus PG, Newman DJ. 2009. Impact of natural products on developing new anti-cancer agents. Chem Rev. 109(7):3012–3043.
  • HemaIswarya S, Doble M. 2006. Potential synergism of natural products in the treatment of cancer. Phytother Res. 20(4):239–249.
  • Newman DJ, Cragg GM. 2016. Natural products as sources of new drugs from 1981 to 2014. J Nat Prod. 79(3):629–661.
  • Sagar S, Esau L, Moosa B, Khashab NM, Bajic VB, Kaur M. 2014. Cytotoxicity and apoptosis induced by a plumbagin derivative in estrogen positive MCF-7 breast cancer cells. Anticancer Agents Med Chem. 14(1):170–180.
  • Shi L, Meng XJ, Cao JQ, Zhao YQ. 2012. A new triterpenoid saponin from Gynostemma pentaphyllum. Nat Prod Res. 26(15):1419–1422.
  • Siegel R, Ma J, Zou Z, Jemal A. 2014. Cancer statistics. CA Cancer J Clin. 64(1):9–29.
  • Stevens KN, Vachon CM, Couch FJ. 2013. Genetic susceptibility to triple-negative breast cancer. Cancer Res. 73(7):2025–2030.
  • Wang K, Zhu X, Zhang K, Zhu L, Zhou FF. 2014. Investigation of gallic acid induced anticancer effect in human breast carcinoma MCF-7 cells. J Biochem Mol Toxicol. 28(9):387–393.
  • Zhang XS, Cao JQ, Zhao C, Wang XD, Wu XJ, Zhao YQ. 2015. Novel dammarane-type triterpenes isolated from hydrolyzate of total Gynostemma pentaphyllum saponins. Bioorg Med Chem Lett. 25(16):3095–3099.
  • Zhang XS, Shi GH, Liu MB, Chen R, Wu XJ, Zhao YQ. 2018. Four new dammarane-type triterpenes derivatives from hydrolyzate of total Gynostemma pentaphyllum saponins and their bioactivities. Nat. Prod. Res. 23:1–7.

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