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Natural Product Research
Formerly Natural Product Letters
Volume 35, 2021 - Issue 12
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Short Communications

A new metabolite from Cunninghamella blakesleeana-mediated biotransformation of an oral contraceptive drug, levonorgestrel

Bates Malikovna Kudaibergenovaa Department of Chemistry, Al-Farabi Kazakh National University, Almaty, Kazakhstan
,
Atia-tul- Wahabb Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, PakistanCorrespondence[email protected] [email protected]
,
Mahwish Siddiquic H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan
,
Zharylkasyn A. Abilova Department of Chemistry, Al-Farabi Kazakh National University, Almaty, Kazakhstan
&
M. Iqbal Choudharya Department of Chemistry, Al-Farabi Kazakh National University, Almaty, Kazakhstan;b Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan;c H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, PakistanCorrespondence[email protected] [email protected]
Pages 2095-2098 | Received 26 Apr 2019, Accepted 30 Jul 2019, Published online: 17 Dec 2019

References

  • Atia-tul-Wahab, Siddiqui M, Ibrahim I, Hussain A, Ajandouz EH, Hijazi A, Baydoun E, Choudhary MI. 2018. Cunninghamella blakesleeana-mediated biotransformation of a contraceptive drug, desogestrel, and anti-MDR-Staphylococcus aureus activity of its metabolites. Bioorg Chem. 77:152–158.
  • Borges KB, de Souza Borges W, Durán-Patrón R, Pupo MT, Bonato PS, Collado IG. 2009. Stereoselective biotransformations using fungi as biocatalysts. Tetrahedron: Asymmetry. 20(4):385–397.
  • Chokchaisiri R, Chaichompoo W, Sukcharoen O, Suksamrarn A, Ganranoo L. 2018. Microbial transformation of isocoronarin D by Cunninghamella echinulata NRRL 1386. Nat Prod Res. 20(33):1–7.
  • Choudhary MI, Sarfraz MA, Nawaz A, Fatmi MQ, Atta-ur-Rahman. 2006. The microbiological hydroxylation of levonorgestrel. Nat Prod Res. 20(12):1074–1081.
  • Choudhary MI, Siddiqui M, Atia-tul-Wahab, Yousuf S, Fatima N, Ahmad MS, Choudhry H. 2017. Bio-catalytic structural transformation of anti-cancer steroid, drostanolone enanthate with Cephalosporium aphidicola and Fusarium lini, and cytotoxic potential evaluation of its metabolites against certain cancer cell lines. Front Pharmacol. 8:900.
  • Shah SAA, Sultan S, Hassan NB, Muhammad FKB, Faridz MABM, Hussain FBM, Hussain M, Adnan HS. 2013. Biotransformation of 17α-ethynyl substituted steroidal drugs with microbial and plant cell cultures: a review. Steroids. 78(14):1312–1324.
  • Shane-McWhorter L, Cerveny JD, MacFarlane LL, Osborn C. 1998. Enhanced metabolism of levonorgestrel during phenobarbital treatment and resultant pregnancy. Pharmacotherapy. 18(6):1360–1364.
  • Xiao Y, Lee IS. 2018. Microbial transformation of quercetin and its prenylated derivatives. Nat Prod Res. 32(8):902–908.

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