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Natural Product Research
Formerly Natural Product Letters
Volume 36, 2022 - Issue 15
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Short Communications

Reassignment of crispatene, isolation and chemical characterization of stachydrine, isolated from the marine mollusk Elysia crispata

Dioni Arriechea Centro de Química “Dr. Gabriel Chuchani”, Laboratorio de Síntesis Orgánica y Productos Naturales, Instituto Venezolano de Investigaciones Científicas (IVIC), Caracas, Venezuela;b Departamento de Química, Universidad Técnica Federico Santa María, Valparaíso, ChileCorrespondence[email protected]
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Alejandra Ugartea Centro de Química “Dr. Gabriel Chuchani”, Laboratorio de Síntesis Orgánica y Productos Naturales, Instituto Venezolano de Investigaciones Científicas (IVIC), Caracas, VenezuelaView further author information
,
Franklin Salazara Centro de Química “Dr. Gabriel Chuchani”, Laboratorio de Síntesis Orgánica y Productos Naturales, Instituto Venezolano de Investigaciones Científicas (IVIC), Caracas, VenezuelaView further author information
,
José E. Villamizara Centro de Química “Dr. Gabriel Chuchani”, Laboratorio de Síntesis Orgánica y Productos Naturales, Instituto Venezolano de Investigaciones Científicas (IVIC), Caracas, VenezuelaView further author information
,
Nelsy Riveroc Departamento de Ciencias Ambientales, Universidad Nacional Experimental Marítima del Caribe (UMC), Catia La Mar, VenezuelaView further author information
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Manuel Caballerd Department of Computer Science, Mathematics and Environmental Sciences, The American University of Paris, Paris, France;e Centro de Oceanología y Estudios Antárticos (COEA), Instituto Venezolano de Investigaciones Científicas (IVIC), Caracas, VenezuelaView further author information
,
Ligia Lloveraf Centro de Química “Dr. Gabriel Chuchani”, Laboratorio de Resonancia Magnética Nuclear, Instituto Venezolano de Investigaciones Científicas (IVIC), Caracas, VenezuelaView further author information
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José Montañezg Universidad Bolivariana de Venezuela, Caracas, VenezuelaView further author information
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Lautaro Taborgab Departamento de Química, Universidad Técnica Federico Santa María, Valparaíso, ChileView further author information
&
Alberto Quinteroa Centro de Química “Dr. Gabriel Chuchani”, Laboratorio de Síntesis Orgánica y Productos Naturales, Instituto Venezolano de Investigaciones Científicas (IVIC), Caracas, VenezuelaView further author information
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Pages 4013-4016 | Received 16 Jun 2020, Accepted 21 Feb 2021, Published online: 07 Mar 2021

References

  • Ireland C, Faulkner J. 1981. The metabolites of the marine molluscs Tridachiella diomedea and Tridachia crispata. Tetrahedron. 37:233–240.
  • Ksebati MB, Schmitz FJ. 1985. Tridachiapyrones : propionate-derived metabolites from the Sacoglossan Mollusc Tridachia crispata. J Org Chem. 50(26):5637–5642.
  • Li L, Lili S, Yan Q, Wenjun Z, Kangyuan H, Junqin M. 2020. Protective effect of stachydrine against cerebral ischemia-reperfusion injury by reducing inflammation and apoptosis through P65 and JAK2/STAT3 signaling pathway. Front Pharmacol. 11:64.
  • Miller AK, Byun DH, Beaudry CM, Trauner D. 2004. The total synthesis of (-)-crispatene. Proc Natl Acad Sci USA. 101 (33):12019– 12023.
  • Mukhamedova KS, Akramov ST, Yunusov SY. 1969. Stachydrine from Capparis spinosa. Chem Nat Prod. 287:60.
  • Paul CM, Zubía E, Ortega MJ, Salvá J. 1997. New polypropionates from Siphonaria pectinata. Tetrahedron. 53(6):2303–2308.
  • Rathee P, Rathee D, Rathee D, Rathee S. 2012. In vitro anticancer activity of stachydrine isolated from Capparis decidua on prostate cancer cell lines. Nat Prod Res. 26(18):1737–1741.
  • Rodríguez J, Riguera R, Debitus C. 1992. New marine cytotoxic bispyrones. Absolute stereochemistry of onchitriols I and II. Tetrahedron Lett. 33(8):1089–1092.

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