Advanced search
Publication Cover
Natural Product Research
Formerly Natural Product Letters
Volume 36, 2022 - Issue 20
Submit an article Journal homepage
235
Views
2
CrossRef citations to date
0
Altmetric
Research Article

A new alkaloid with cytotoxic activity from Fritillaria thunbergii Miq

Cuilin Hea Department of Medicinal Natural Products, West China School of Pharmacy, Sichuan University, Chengdu, China
,
Xinghong Liua Department of Medicinal Natural Products, West China School of Pharmacy, Sichuan University, Chengdu, China
,
Youran Liua Department of Medicinal Natural Products, West China School of Pharmacy, Sichuan University, Chengdu, China
,
Jianzhong Wanga Department of Medicinal Natural Products, West China School of Pharmacy, Sichuan University, Chengdu, China
&
Donglin Chena Department of Medicinal Natural Products, West China School of Pharmacy, Sichuan University, Chengdu, China;b Key Laboratory of Drug Targeting and Drug Delivery System Ministry of Education, West China School of Pharmacy, Sichuan University, Chengdu, ChinaCorrespondence[email protected]
Pages 5297-5303 | Received 03 Feb 2021, Accepted 18 May 2021, Published online: 01 Jun 2021

References

  • Hu Z, Zong JF, Yili A, Yu MH, Aisa HA, Hou AJ. 2018. Isosteroidal alkaloids from the bulbs of Fritillaria tortifolia. Fitoterapia. 131:112–118.
  • Ito S, Kato M, Shibata K, Nozoe T. 1963. On the alkaloid of Fritillaria verticillate WILD. var. Thunbergii BAKER. II. The structure of verticine. Chem Pharm Bull. 11(10):1337–1340.
  • Li Q, Long CB, Zhu PF, Liu YP, Luo XD. 2019. Seven new veratramine-type alkaloids with potent analgesic effect from Veratrum taliense. J Ethnopharmacol. 244:112137.
  • Li Y, Yili A, Li J, Muhamat A, Aisa HA. 2016. New isosteroidal alkaloids with tracheal relaxant effect from the bulbs of Fritillaria pallidiflora Schrenk. Bioorg Med Chem Lett. 26(8):1983–1987.
  • Liu YM, Feng YD, Lu X, Nie JB, Li W, Wang LN, Tian LJ, Liu QH. 2017. Isosteroidal alkaloids as potent dual-binding site inhibitors of both acetylcholinesterase and butyrylcholinesterase from the bulbs of Fritillaria walujewii. Eur J Med Chem. 137:280–291.
  • Mosmann T. 1983. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods. 65(1–2):55–63.
  • Nuriddinov RN, Yunusov SY. 1969. Structure and configuration of edpetilidine and eduardine. Chem Nat Compd. 5(4):284–285.
  • Plumb JA. 2004. Cell sensitivity assays: clonogenic assay. Methods Mol Med. 88:159–164.
  • Rieger AM, Nelson KL, Konowalchuk JD, Barreda DR. 2011. Modified Annexin V/propidium iodide apoptosis assay for accurate assessment of cell death. J Visualized Exp. 50:2597
  • Shou QY, Tan Q, Shen ZW. 2010. Two 22S-solanidine-type steroidal alkaloids from Fritillaria anhuiensis. Fitoterapia. 81(2):81–84.
  • Wang D, Yang J, Du Q, Li H, Wang S. 2016. The total alkaloid fraction of bulbs of Fritillaria cirrhosa displays anti-inflammatory activity and attenuates acute lung injury. J Ethnopharmacol. 193:150–158.
  • Won SS, Seung YL, Jong EP, Dong HK, Sun YK, Kang RL. 2018. Two new steroidal alkaloids from the bulbs of Fritillaria thunbergii. Heterocycles. 96(5):921–930.
  • Yang ZD, Duan DZ. 2012. A new alkaloid from Fritillaria ussuriensis Maxim. Fitoterapia. 83(1):137–141.
  • Zhang JX, Ma GE, Nao AL, Xu RS. 1991. Studies on chemical constituents of Fritillaria thunbergii Miq. Acta Pharm Sin. 26(3):231–233.
  • Zhang YH, Zhang QJ, Zheng ZF, Yu DQ. 2011. Steroidal alkaloids from the bulbs of Fritillaria unibracteata. J. Asian Nat. Prod. Res. 13(12):1098–1103.
  • Zhang YH, Yang XL, Zhang P, et al. 2008. Cytotoxic Alkaloids from the Bulbs of Fritillaria hupehensis. Chem Biodivers. 5(2):259–266.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.