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Natural Product Research
Formerly Natural Product Letters
Volume 36, 2022 - Issue 20
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Research Article

Two new alkaloids from Tibetan medicine of Hypecoum leptocarpum

Bo Suna Department of Pharmaceutical Engineering, School of Chemistry and Chemical Engineering and Jiangsu Province Hi-Tech Key Laboratory for Biomedical Research, Southeast University, Nanjing, ChinaView further author information
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Israa Assania Department of Pharmaceutical Engineering, School of Chemistry and Chemical Engineering and Jiangsu Province Hi-Tech Key Laboratory for Biomedical Research, Southeast University, Nanjing, ChinaORCID Iconhttps://orcid.org/0000-0002-2234-8847View further author information
ORCID Icon,
Chun-Gu Wanga Department of Pharmaceutical Engineering, School of Chemistry and Chemical Engineering and Jiangsu Province Hi-Tech Key Laboratory for Biomedical Research, Southeast University, Nanjing, ChinaView further author information
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Mu-Xuan Wanga Department of Pharmaceutical Engineering, School of Chemistry and Chemical Engineering and Jiangsu Province Hi-Tech Key Laboratory for Biomedical Research, Southeast University, Nanjing, ChinaView further author information
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Ling-Fei Liua Department of Pharmaceutical Engineering, School of Chemistry and Chemical Engineering and Jiangsu Province Hi-Tech Key Laboratory for Biomedical Research, Southeast University, Nanjing, ChinaView further author information
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Yan Lia Department of Pharmaceutical Engineering, School of Chemistry and Chemical Engineering and Jiangsu Province Hi-Tech Key Laboratory for Biomedical Research, Southeast University, Nanjing, ChinaView further author information
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Ge Yana Department of Pharmaceutical Engineering, School of Chemistry and Chemical Engineering and Jiangsu Province Hi-Tech Key Laboratory for Biomedical Research, Southeast University, Nanjing, ChinaView further author information
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Yun-Ruo Yanga Department of Pharmaceutical Engineering, School of Chemistry and Chemical Engineering and Jiangsu Province Hi-Tech Key Laboratory for Biomedical Research, Southeast University, Nanjing, ChinaView further author information
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Zhi Chenb Key Laboratory of Medicinal Animal and Plant Resources of Qinghai-Tibetan Plateau in Qinghai Province, Xining, ChinaCorrespondence[email protected] [email protected]
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Zhi-Xin Liaoa Department of Pharmaceutical Engineering, School of Chemistry and Chemical Engineering and Jiangsu Province Hi-Tech Key Laboratory for Biomedical Research, Southeast University, Nanjing, ChinaCorrespondence[email protected] [email protected]
View further author information
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Pages 5304-5310 | Received 17 Feb 2021, Accepted 25 May 2021, Published online: 16 Jun 2021

References

  • Foon-Chew How, Te-Lin Wu. 1982. A dictionary of the families and genera of Chinese seed plants. Sci Press Beijing; p.285.
  • Li BG, Zhou M, Zhang GL. 2001. Four new alkaloids from Hypecoum leptocarpum Hook. f. et Thoms. Indian J Chem Sect B-Org Med Chem. 40(12):1215–1218.
  • Li J, Meng X, Wang C, Zhang H, Chen H, Deng P, Liu J, Huandike M, Wei J, Chai L. 2020. Coptidis alkaloids extracted from Coptis chinensis Franch attenuate IFN-γ-induced destruction of bone marrow cells. PLoS One. 15(7):e0236433.
  • Lin L, Li XY, Liu SS, Qing ZX, Liu XB, Zeng JG, Liu ZY. 2020. Systematic identification of compounds in Macleaya microcarpa by high-performance liquid chromatography/quadrupole time-of-flight tandem mass spectrometry combined with mass spectral fragmentation behavior of Macleaya alkaloids. Rapid Commun Mass Spectrom. 34(9):e8715.
  • Liu D, Meng X, Wu D, Qiu Z, Luo H. 2019. A natural isoquinoline alkaloid with antitumor activity: Studies of the biological activities of berberine. Front Pharmacol. 10:1–12.
  • Liu SL, Kao CL, Pan JY, Li HT, Chen CY. 2020. A New Diester from the Flowers of Michelia fuscata. Chem Nat Compd. 56(3):400–402.
  • Liu Y, Wang W, Che F, Lu Y, Li A, Li H, Liu J, Wei Y. 2020. Isolation and purification of alkaloids from the fruits of Macleaya cordata by ionic-liquid-modified high-speed counter-current chromatography. J Sep Sci. 43(12):2459–2466.
  • Oyuntsetseg N, Khasnatinov MA, Molor-Erdene P, Oyunbileg J, Liapunov AV, Danchinova GA, Oldokh S, Baigalmaa J, Chimedragchaa C. 2014. Evaluation of direct antiviral activity of the Deva-5 herb formulation and extracts of five Asian plants against influenza A virus H3N8. BMC Complement Altern Med. 14:235.
  • Qing ZX, Huang JL, Yang XY, Liu JH, Cao HL, Xiang F, Cheng P, Zeng JG. 2018. Anticancer and reversing multidrug resistance activities of natural isoquinoline alkaloids and their structure-activity relationship. Curr Med Chem. 25(38):5088–5114.
  • Qing ZX, Yang P, Tang Q, Cheng P, Liu XB, Zheng Y, Liu YS, Zeng JG. 2017. Isoquinoline alkaloids and their antiviral, antibacterial, and antifungal activities and structure–activity relationship. Curr Org Chem. 21(18):1920–1934.
  • Rücker G, Breitmaier E, Zhang GL, Mayer R. 1994. Alkaloids from Dactylicapnos torulosa. Phytochemistry. 36(2):519–523.
  • Seger C, Sturm S, Strasser EM, Ellmerer E, Stuppner H. 2004. 1H and 13C NMR signal assignment of benzylisoquinoline alkaloids from Fumaria officinalis L. (Papaveraceae). Magn Reson Chem. 42(10):882–886.
  • Shang XF, Yang CJ, Morris-Natschke SL, Li JC, Yin XD, Liu YQ, Guo X, Peng JW, Goto M, Zhang JY, et al. 2020. Biologically active isoquinoline alkaloids covering 2014–2018. Med Res Rev. 40(6):2212–2219.
  • Wang Q, Chen W, Wang Q, Tao Y, Yu R, Pan G, Dang J. 2020. Preparative separation of isoquinoline alkaloids from Corydalis impatiens using middle chromatogram isolated gel column coupled with positively charged reversed-phase liquid chromatography. J Sep Sci. 43(13):2521–2528.
  • Wen HX, Shao B, Tao YD, Yue HL. 2019. A Method and Application of an Isoquinoline Alkaloid Compound. [P]. CHINA: 109206429.
  • Wen HX, Jiang L, Zhang D, Yuan X, Dang J, Mei L, Shao Y, Tao Y. 2018. Anti-inflammatory activity of total alkaloids from Hypecoum leptocarpum Hook. f. et Thoms. Phcog Mag. 14(56):397–403.
  • Xia JK, Liu Y, Zhou Y, Zhang JY, Li CH, Yin X, Tian XR, Zhang XY. 2020. Two novel alkaloids from Corydalis curviflora Maxim. and their insecticidal activity. Pest Manag Sci. 76(7):2360–2367.
  • Yin X, Bai R, Guo Q, Su G, Wang J, Yang X, Li L, Tu P, Chai X. 2016. Hendersine A, a novel isoquinoline alkaloid from Corydalis hendersonii. Tetrahedron Lett. 57(43):4858–4862.
  • Zhang B, Huang R, Hua J, Liang H, Pan Y, Dai L, Liang D, Wang H. 2016. Antitumor lignanamides from the aerial parts of Corydalis saxicola. Phytomedicine. 23(13):1599–1609.
  • Zhang GL, Rücker G, Breitmaier E, Mayer R. 1995. Alkaloids from Hypecoum leptocarpum. Phytochemistry. 40(6):1813–1816.
  • Zhang Q, Luan G, Ma T, Hu N, Suo Y, Wang X, Ma X, Ding C. 2015. Application of chromatography technology in the separation of active alkaloids from Hypecoum leptocarpum and their inhibitory effect on fatty acid synthase. J Sep Sci. 38(23):4063–4070.
  • Zhao SF, He Y, Wang CG, Israa A, Hou PL, Feng Y, Yang JJ, Wang YH, Liao ZX, Shen SD. 2020. Isolation, Characterization and bioactive properties of alkali-extracted polysaccharides from Enteromorpha prolifera. Mar. Drugs. 18(11):552.
  • Zhou Y, Zhang G, Li B. 1999. Five alkaloids from Hypecoum leptocarpum. Phytochemistry. 50(2):339–343.

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