Hypoglycemic effect of rosmarinic acid-rich infusion (RosCE) from Origanum vulgare in alloxan-induced diabetic rats

References

• Baranauskaitė J, Jakštas V, Ivanauskas L, Kopustinskienė DM, Drakšienė G, Masteikova R, Bernatonienė J. 2016. Optimization of carvacrol, rosmarinic, oleanolic and ursolic acid extraction from oregano herbs (Origanum onites L., Origanum vulgare spp. hirtum and Origanum vulgare L.). Nat Prod Res. 30(6):672–674.
   PubMed Web of Science ®Google Scholar
• Cunha WR, Arantes GM, Ferreira DS, Lucarini R, Silva MLA, Furtado NAJC, da Silva Filho AA, Crotti AEM, Araújo ARB. 2008. Hypoglicemic effect of Leandra lacunosa in normal and alloxan-induced diabetic rats. Fitoterapia. 79(5):356–360.
   PubMed Web of Science ®Google Scholar
• Ding HY, Chou TH, Liang CH. 2010. Antioxidant and antimelanogenic properties of rosmarinic acid methyl ester from Origanum vulgare. Food Chem. 123(2):254–262.
   Web of Science ®Google Scholar
• Flor LS, Campos MR. 2017. The prevalence of diabetes mellitus and its associated factors in the Brazilian adult population: evidence from a population-based survey. Rev Bras Epidemiol. 20(1):16–29.
   PubMedGoogle Scholar
• Grondona E, Gatti G, López AG, Sánchez LR, Rivero V, Pessah O, Zunino MP, Ponce AA. 2014. Bio-efficacy of the essential oil of oregano (Origanum vulgare Lamiaceae. Ssp. Hirtum). Plant Foods Hum Nutr. 69(4):351–357.
   PubMed Web of Science ®Google Scholar
• Hitl M, Kladar N, Gavarić N, Božin B. 2021. Rosmarinic acid-human pharmacokinetics and health benefits. Planta Med. 87(4):273–282.
   PubMedGoogle Scholar
• Jayanthy G, Subramanian S. 2015. RA abrogates hepatic gluconeogenesis and insulin resistance by enhancing IRS-1 and AMPK signalling in experimental type 2 diabetes. RSC Adv. 5(55):44053–44067.
   Web of Science ®Google Scholar
• Kosakowska O, Węglarz Z, Pióro-Jabrucka E, Przybył JL, Kraśniewska K, Gniewosz M, Bączek K. 2021. Antioxidant and antibacterial activity of essential oils and hydroethanolic extracts of Greek Oregano (O. vulgare L. subsp. hirtum (Link) Ietswaart) and common Oregano (O. vulgare L. subsp. vulgare). Molecules. 26(4):988.
   PubMed Web of Science ®Google Scholar
• Kwon YI, Vattem DA, Shetty K. 2006. Evaluation of clonal herbs of Lamiaceae species for management of diabetes and hypertension. Asia Pac J Clin Nutr. 15(1):107–118.
   PubMed Web of Science ®Google Scholar
• Laskarina MK, Ioannis B, Panagiotis M, Ilias D, Panagiotis K, Aspasia T, Anastasia P, Eleni P, Athanasios B, Despina NP. 2016. Medicinal properties of Mediterranean plants against glucose and lipid disorders. J Med Plants Stud. 4(3):94–100.
   Google Scholar
• Lemhadri A, Zeggwagh NA, Maghrani M, Jouad H, Eddouks M. 2004. Anti-hyperglycaemic activity of the aqueous extract of Origanum vulgare growing wild in Tafilalet region. J Ethnopharmacol. 92(2-3):251–256.
   PubMed Web of Science ®Google Scholar
• Luo C, Sun H, Peng J, Gao C, Bao L, Ji R, Zhang C, Zhu W, Jin Y. 2021. Rosmarinic acid exerts an antagonistic effect on nonalcoholic fatty liver disease by regulating the YAP1/TAZ-PPARγ/PGC-1α signaling pathway. Phytother Res. 35(2):1010–1022.
   PubMed Web of Science ®Google Scholar
• Mariadoss AVA, Park S, Saravanakumar K, Sathiyaseelan A, Wang M-H. 2021. Ethyl acetate fraction of Helianthus tuberosus L. 2021. Induces anti-diabetic and wound-healing activities in insulin-resistant human liver cancer and mouse fibroblast cells. Antioxidants. 10(1):99.
   Web of Science ®Google Scholar
• Paloukopoulou C, Govari S, Soulioti A, Stefanis I, Angeli A, Matheeussen A, Capasso C, Cos P, Supuran CT, Karioti A. 2021. Phenols from Origanum dictamnus L. and Thymus vulgaris L. and their activity against Malassezia globosa carbonic anhydrase. Nat Prod Res. 3:1–7.
   Google Scholar
• Patel DK, Prasad SK, Kumar R, Hemalatha S. 2012. An overview on antidiabetic medicinal plants having insulin mimetic property. Asian Pac J Trop Biomed. 2(4):320–330.
   PubMedGoogle Scholar
• Rahman MM, Uddin MJ, Reza ASMA, Tareq AM, Emran TB, Simal-Gandara J. 2021. Ethnomedicinal Value of Antidiabetic Plants in Bangladesh: A Comprehensive Review. Plants. 10(4):729.
   Google Scholar
• Ramalingum N, Mahomoodally MF. 2014. The therapeutic potential of medicinal foods. Adv Pharmacol Sci. 2014:354264.
   PubMedGoogle Scholar
• Rubin B, Manso J, Monticelli H, Bertazza L, Redaelli M, Sensi F, Zorzan M, Scaroni C, Mian C, Iacobone M, et al. 2019. Crude extract of Origanum vulgare L. induced cell death and suppressed MAPK and PI3/Akt signaling pathways in SW13 and H295R cell lines. Nat Prod Res. 33(11):1646–1649.
   PubMed Web of Science ®Google Scholar
• Salvo A, La Torre GL, Rotondo A, Cicero N, Gargano R, Mangano V, Casale KE, Dugo G. 2019. Multiple analytical approaches for the organic and inorganic characterization of Origanum vulgare L. samples. Nat Prod Res. 33(19):2815–2822.
   PubMed Web of Science ®Google Scholar
• Sarikurkcu C, Zengin G, Oskay M, Uysal S, Ceylan R, Aktumsek A. 2015. Composition, antioxidant, antimicrobial, and enzyme inhibition activities of two Origanum vulgare sub-species (subsp. vulgare and subsp. hirtum) essential oils. Ind Crops Prod. 70:178–184.
   Web of Science ®Google Scholar
• Spiridon I, Colceru S, Anghel N, Teaca CA, Bodirlau R, Armatu A. 2011. Antioxidant capacity and total phenolic contents of oregano (Origanum vulgare), lavender (Lavandula angustifolia) and lemon balm (Melissa officinalis) from Romania. Nat Prod Res. 25(17):1657–1661.
   PubMed Web of Science ®Google Scholar
• Tair A, Weiss EK, Palade LM, Loupassaki S, Makris DP, Ioannou E, Roussis V, Kefalas P. 2014. Origanum species native to the island of Crete: in vitro antioxidant characteristics and liquid chromatography-mass spectrometry identification of major polyphenolic components. Nat Prod Res. 28(16):1284–1287.
   PubMed Web of Science ®Google Scholar
• Teixeira B, Marques A, Ramos C, Serrano M, Matos O, Neng N, Nogueira J, Saraiva J, Nunes M. 2013. Chemical composition and bioactivity of different oregano (Origanum vulgare) extracts and essential oil. J Sci Food Agric. 93(11):2707–2714. 10.1002/jsfa.6089.
   PubMed Web of Science ®Google Scholar
• Tepe B, Sokmen A. 2007. Production and optimisation of rosmarinic acid by Satureja hortensis L. callus cultures. Nat Prod Res. 21(13):1133–1144.
   PubMed Web of Science ®Google Scholar
• Vujicic M, Nikolic I, Kontogianni VG, Saksida T, Charisiadis P, Orescanin-Dusic Z, Blagojevic D, Stosic- Grujicic S, Tzakos AG, Stojanovic I. 2015. Methanolic extract of Origanum vulgare ameliorates type 1 diabetes through antioxidant, anti-inflammatory and anti-apoptotic activity. Br J Nutr. 113(5):770–782.
   PubMed Web of Science ®Google Scholar
• Vujicic M, Nikolic I, Kontogianni VG, Saksida T, Charisiadis P, Vasic B, Stosic-Grujicic S, Gerothanassis IP, Tzakos AG, Stojanovic I. 2016. Ethyl acetate extract of Origanum vulgare L. ssp. Hirtum prevents streptozotocin-induced diabetes in C57BL/6 Mice. J Food Sci. 81(7):H1846–H1853.
   PubMed Web of Science ®Google Scholar
• Wang GY, Chen SY, Chen YY, Hong CJ, Hsu YH, Yen GC. 2021. Protective effect of rosmarinic acid-rich trichodesma khasianum clarke leaves against ethanol-induced gastric mucosal injury in vitro and in vivo. Phytomedicine. 80:153382.
   PubMed Web of Science ®Google Scholar
• Yu H, Zhang P, Liu H, Sun X, Liang J, Sun L, Chen Y. 2021. Hypoglycemic activity of Origanum vulgare L. and its main chemical constituents identified with HPLC-ESI-QTOF-MS. Food Funct. 12(6):2580–2590.
   PubMed Web of Science ®Google Scholar