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Natural Product Research
Formerly Natural Product Letters
Volume 37, 2023 - Issue 10
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Short Communication

In vitro antioxidant and anti-inflammatory activity of an oleuropein-enriched extract obtained from olives leaves on BME-UV1 cells

Loredana BasiricòDepartment of Agriculture and Forest Sciences (DAFNE), University of Tuscia, Via S. Camillo de Lellis, Viterbo, ItalyORCID Iconhttps://orcid.org/0000-0002-4738-3622View further author information
ORCID Icon,
Fabio MastrogiovanniDepartment of Agriculture and Forest Sciences (DAFNE), University of Tuscia, Via S. Camillo de Lellis, Viterbo, ItalyORCID Iconhttps://orcid.org/0000-0003-4858-7501View further author information
ORCID Icon,
Nicola LaceteraDepartment of Agriculture and Forest Sciences (DAFNE), University of Tuscia, Via S. Camillo de Lellis, Viterbo, ItalyORCID Iconhttps://orcid.org/0000-0003-2088-2744View further author information
ORCID Icon,
Luca SantiDepartment of Agriculture and Forest Sciences (DAFNE), University of Tuscia, Via S. Camillo de Lellis, Viterbo, ItalyORCID Iconhttps://orcid.org/0000-0003-4638-5084View further author information
ORCID Icon,
Roberta BerniniDepartment of Agriculture and Forest Sciences (DAFNE), University of Tuscia, Via S. Camillo de Lellis, Viterbo, ItalyCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-2548-3876View further author information
ORCID Icon &
Umberto BernabucciDepartment of Agriculture and Forest Sciences (DAFNE), University of Tuscia, Via S. Camillo de Lellis, Viterbo, ItalyORCID Iconhttps://orcid.org/0000-0002-8126-3042View further author information
ORCID Icon
Pages 1725-1729 | Received 07 Jun 2022, Accepted 22 Jul 2022, Published online: 03 Aug 2022

References

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  • Mastrogiovanni F, Mukhopadhya A, Lacetera N, Ryan MT, Romani A, Bernini R, Sweeney T. 2019. Anti-inflammatory effects of pomegranate peel extracts on in vitro human intestinal Caco-2 cells and ex vivo porcine colonic tissue explants. Nutrients. 11(3):548–562.
  • Mastrogiovanni F, Bernini R, Basiricò L, Bernabucci U, Campo M, Romani A, Santi L, Lacetera N. 2020. Antioxidant and anti-inflammatory effects of pomegranate peel extracts on bovine mammary epithelial cells BME-UV1. Nat Prod Res. 34(10):1465–1469.
  • Park J, Ju-Sik M, Unbin C, Yeop LJ, Kyung-Sik S, Hyun-Shik L, Jun LH, Sang-Rae L, Dong-Seok L. 2017. Anti-inflammatory effect of oleuropein on microglia through regulation of Drp1-dependent mitochondrial fission. J Neuroimmunol. 306:46–52.
  • Qabaha K, AL-Rimawi F, Qasem A, Naser SA. 2018. Oleuropein is responsible for the major anti-inflammatory effects of olive leaf extract. J Med Food. 21(3):302–305.
  • Romani A, Pinelli P, Ieri F, Bernini R. 2016. Sustainability, innovation, and green chemistry in the production and valorization of phenolic extracts from Olea europaea L. Sustainability. 8(10):1002–1011.
  • Romani A, Ieri F, Urciuoli S, Noce A, Marrone G, Nediani C, Bernini R. 2019. Health effects of phenolic compounds found in extra-virgin olive oil, by-products, and leaf of Olea europaea L. Nutrients. 11(8):1776–1802.
  • Ryu SJ, Choi HS, Yoon KY, Lee OH, Kim KJ, Lee BY. 2015. Oleuropein suppresses LPS-induced inflammatory responses in RAW264.7 cell and zebrafish. J Agric Food Chem. 63(7):2098–2105.
  • Stahel WR. 2016. The circular economy. Nature. 531(7595):435–438.

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