References
- Claudio VJ, AD, da Vanderlan SB, Eliezer JB, Carlos AMF. 2007. Molecular hybridization: a useful tool in the design of new drug prototypes. Curr Med Chem. 14(17):1829–1852.
- Cui HQ, Wang XH, Zhao CK, Pu Y, Wang HY. 2020. Selective alkylation of β-anhydroicaritine and their biological evaluation on anticancer. Nat Prod Res. e1844686.
- Fortin S, Bérubé G. 2013. Advances in the development of hybrid anticancer drugs. Expert Opin Drug Discov. 8(8):1029–1047.
- Kerru N, Singh P, Koorbanally N, Raghu R, Kumar V. 2017. Recent advances (2015–2016) in anticancer hybrids. Eur J Med Chem. 142:179–212.
- Kumar A, Kumar S. 2020. Coumarin-chalcone hybrids for biological potentials: a strategy of molecular hybridization for drug design. IJPSRR. 64(2):146–151.
- Lan Q, Zhou YQ, Wang XH, Wang YH, Zhao CK. 2021. Synthesis and biological evaluation of camptothecin substituted norcantharimide derivatives. Nat Prod Res. 35(24):5752–5756.
- Lichota A, Gwozdzinski K. 2018. Anticancer activity of natural compounds from plant and marine environment. IJMS 19(11):3533.
- Liu M, Zhang WJ, Gao N. 2009. Splicing principle and its application in new drug design. Huaxue Shiji. 850:795–797.
- Lu JJ, Wang YT. 2020. Identification of anti-cancer compounds from natural products. Chin J Nat Med. 18(7):481–482.
- Petrelli A, Giordano S. 2008. From single- to multi-target drugs in cancer therapy: when a specificity becomes an advantage. Curr Med Chem. 15(5):422–432.
- Scotti L, Scotti MT, Ishiki H, Francisco JBMJ, Silva MSD. 2014. Prediction of anticancer activity of diterpenes isolated from the paraiban flora through a PLS model and molecular surfaces. Nat Prod Comm. 9(5):609–612.
- Stierle A. 2018. Review of cancer inhibitors from Chinese natural medicines. J Nat Prod. 81(4):1125–1126.
- Wang XH, Zhao CK, Jia J, Luo CM, Li XF. 2016. Mono-ester derivatives of norcantharidin mono-acid and their antitumor application. CN201610451738.9
- Yang T, Chao G, Liu YY, Pan JN. 2020. Mechanism of action and clinical research progress of molecular targeted antitumor drugs. Elec J Clin Med Lit. 7(31):1.
- Zhao CK, Li C, Wang XH, Bao YJ, Yang FH, Huang M. 2018. The regio-selective synthesis of 10-hydroxy camptothecin norcantharidin conjugates and their biological activity evaluation in vitro. R Soc Open Sci. 5(6):172317.
- Zhao CK, Wang XH, Jia J, Cao Y, Bao YJ. 2018. Ring open to mono ester of norcantharidin derivatives also can inhibit Hep G2 cell line? Lat Am J Pharm. 37(3):470–474.
- Zhao CK, Wang XH, Yang FH, Gao L, Wang YH. 2018. A simple route to a novel acid-sensitive 20(S)-O-linked camptothecin norcantharidin acid ester derivative. R Soc Open Sci. 5(2):170842.
- Zhao CK, Xu L, Wang XH, Bao YJ, Wang YH. 2019. Synthesis of dual target CPT-Ala-Nor conjugates and their biological activity evaluation. Anticancer Agents Med Chem. 19(4):502–508.