Advanced search
Publication Cover
Natural Product Research
Formerly Natural Product Letters
Volume 38, 2024 - Issue 11
Submit an article Journal homepage
228
Views
0
CrossRef citations to date
0
Altmetric
Research Article

A novel carissic acid from fruits of Carissa carandas induced apoptotic cell death in A-549 cells following the activation of caspases

Navneet Koura Division of Biochemistry, Faculty of Basic Sciences, Sher-e-Kashmir University of Agricultural Sciences and Technology of Jammu, Chatha, Jammu, Jammu & Kashmir, IndiaView further author information
,
Arem Qayumb Pharmacology Division, CSIR-Indian Institute of Integrative Medicine, Jammu, Jammu & Kashmir, IndiaView further author information
,
Bashir A. Lonec Academy of Scientific & Innovative Research (AcSIR), Ghaziabad, India;d Natural Products and Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine, Jammu, Jammu & Kashmir, IndiaView further author information
,
Shashank K Singhb Pharmacology Division, CSIR-Indian Institute of Integrative Medicine, Jammu, Jammu & Kashmir, India;c Academy of Scientific & Innovative Research (AcSIR), Ghaziabad, IndiaView further author information
,
Vikas Sharmaa Division of Biochemistry, Faculty of Basic Sciences, Sher-e-Kashmir University of Agricultural Sciences and Technology of Jammu, Chatha, Jammu, Jammu & Kashmir, IndiaCorrespondence[email protected]
View further author information
&
Prasoon Guptac Academy of Scientific & Innovative Research (AcSIR), Ghaziabad, India;d Natural Products and Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine, Jammu, Jammu & Kashmir, IndiaCorrespondence[email protected]
View further author information
Pages 1887-1897 | Received 14 Jul 2022, Accepted 24 Jun 2023, Published online: 14 Jul 2023

References

  • Agarwal T, Singh R, Shukla AD, Waris I. 2012. In vitro study of antibacterial activity of Carissa carandas leaf extracts. Asian J Plant Sci Res. 2(1):36–40.
  • American Cancer Society. 2016. Cancer facts & figures. Atlanta (GA): American Cancer Society.
  • Bankar GJ, Verma SK, Prasad RN. 1994. Fruit for the arid regions: Karaunda. Ind J Hortic. 39:46–47.
  • Banskota S, Regmi SC, Kim JA. 2015. NOX1 to NOX2 switch deactivates AMPK and induces invasive phenotype in colon cancer cells through overexpression of MMP-7. Mol Cancer. 14:123–129. doi: 10.1186/s12943-015-0379-0.
  • Bhaskar VH, Balakrishnan N. 2009. Analgesic, anti-inflammatory and antipyretic activities of Pergularia daemia and Carissa carandas. DARU J Pharma Sci. 17(3):168–174.
  • Boeing H, Bechthold A, Bub A, Ellinger S, Haller D, Kroke A, Leschik-Bonnet E, Müller MJ, Oberritter H, Schulze M, et al. 2012. Critical review: vegetables and fruit in the prevention of chronic diseases. Eur J Nutri. 51(6):637–663. doi: 10.1007/s00394-012-0380-y.
  • Donaldson MS. 2004. Nutrition and cancer: a review of the evidence for an anti-cancer diet. Nutri J. 3(1):1–21
  • Itankar PR, Lokhande SJ, Verma PR, Arora SK, Sahu RA, Patil AT. 2011. Antidiabetic potential of unripe Carissa carandas Linn. fruit extract. J Ethnopharmacol. 135(2):430–433. doi: 10.1016/j.jep.2011.03.036.
  • Kug CK, Jin SK, Jung KS, Gyu K. 2007. Enhance induction of mitochondrial damage and apoptosis in leukemia HL-60 cells by the Ganodermalucidum and Duchesneachysantha extracts. Cancer Lett. 246(1):210–217.
  • Lim TK. 2012. Edible medicinal and non-medicinal plants. Vol. 1. New York: Springer.
  • Nianyu L, Kathy R, Gretchen L, Jennie S, Bartek R, Melendez JA, Robinson JP. 2003. DPI induces mitochondrial superoxide-mediated apoptosis. Free Rad Biol Med. 34(4):465–477. doi: 10.1016/s0891-5849(02)01325-4.
  • Nirmala MJ, Samundeeswari A, Sankar PD. 2011. Natural plant resources in anti-cancer therapy—A review. Res Plant Biol. 1(3):23–31.
  • Papanov G, Bozob P, Malakov P. 1992. Triterpenoids from Lavandulaspica. Phytochemistry. 31:1424–1426. doi: 10.1016/0031-9422(92)80309-3.
  • Pullaiah T. 2006. Encyclopaedia of world medicinal plants. Vol. 1. New Delhi (India): Regency Publications.
  • Shwe HH, Win KK, Moe TT, Myint AA, Win T. 2019. Isolation and structural characterization of lupeol from the stem bark of Diospyros ehretioides wall. Int Eur Ext Sci Eng Man. 7(8):140–144.
  • Siegel R, Ma J, Zou Z, Jemal A. 2014. Cancer statistics. CA Cancer J Clin. 64(1):9–29. doi: 10.3322/caac.21208.
  • Siegel RL, Miller KD, Jemal A. 2016. Cancer statistics. Cancer J Clin. 66(1):7–30. doi: 10.3322/caac.21332.
  • Sumbul S, Ahmed SI. 2012. Anti-hyperlipidemic activity of Carissa carandas (Auct.) leaves extract in egg yolk induced hyperlipidemic rats. J Basic Appl Sci. 8(1):124–134. doi: 10.6000/1927-5129.2012.08.01.07.
  • Tijjani A, Ndukwe IG, Ayo RG. 2012. Isolation and characterization of Lup-20(29)-ene-3, 28-diol (Betulin) from the stem-bark of Adeniumobesum (Apocynaceae). Trop J Pharm Res. 11(2):259–262. doi: 10.4314/tjpr.v11i2.12.
  • Vichai V, Kirtikara K. 2006. Sulforhodamine B colorimetric assay for cytotoxicity screening. Nat Protoc. 1(3):1112–1116. doi: 10.1038/nprot.2006.179.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.