Heptaellipside A, a rare new 2,28-bidesmosidic lupane-type saponin from the leaves of Heptapleurum ellipticum

References

• Aman M, Rai Vittal R, Samaga PV. 2010. Antimicrobial and phytochemical screening of Boswellia serrata Roxb., Rhus mysorensis Heyne, Strychnos potatorum Linn. F. and Schefflera stellata Gaertn. Med Aromat Plant Sci Biotechnol. 4:69–72.
   Google Scholar
• Braca A, Abdel-Razik AF, Mendez J, De Tommasi N. 2006. Triterpenoid saponins from Campsiandra guayanensis. J Nat Prod. 69(2):240–246. doi:10.1021/np050429+.
   PubMed Web of Science ®Google Scholar
• Bui VM, Huynh BLC, Pham NKT, Nguyen TAT, Nguyen TTT, Nguyen KPP, Nguyen TP. 2022. Usneaceratins A and B, two new secondary metabolites from the lichen Usnea ceratina. Nat Prod Res. 36:3944–3949.
   Web of Science ®Google Scholar
• Chen Y, Tao S, Zeng F, Xie L, Shen Z. 2015. Antinociceptive and anti-inflammatory activities of Schefflera octophylla extracts. J Ethnopharmacol. 171:42–50. doi:10.1016/j.jep.2015.04.050.
   PubMed Web of Science ®Google Scholar
• Cheng Q, Cai S, Ni D, Wang R, Zhou F, Ji B, Chen Y. 2015. In vitro antioxidant and pancreatic α-amylase inhibitory activity of isolated fractions from water extract of Qingzhuan tea. J Food Sci Technol. 52(2):928–935. doi:10.1007/s13197-013-1059-y.
   PubMed Web of Science ®Google Scholar
• Do VM, Tran CL, Nguyen TP. 2020. Polysciosides J and K, two new oleanane-type triterpenoid saponins from the leaves of Polyscias fruticosa (L.) Harms. cultivating in An Giang Province, Viet Nam. Nat Prod Res. 34(9):1250–1255. doi:10.1080/14786419.2018.1557657.
   PubMed Web of Science ®Google Scholar
• Gauthier C, Legault J, Lavoie S, Rondeau S, Tremblay S, Pichette A. 2009. Synthesis and cytotoxicity of bidesmosidic betulin and betulinic acid saponins. J Nat Prod. 72(1):72–81. doi:10.1021/np800579x.
   PubMed Web of Science ®Google Scholar
• Hansen L, Boll PM. 1986. The polyacetylenic falcarinol as the major allergen in Schefflera arboricola. Phytochemistry. 25(2):529–530. doi:10.1016/S0031-9422(00)85517-X.
   Web of Science ®Google Scholar
• Hebbar DR, Nalini MS. 2014. Evaluation of phytochemicals, total phenolics and antioxidant activities of Schefflera spp. (Araliaceae) from southern India. J Pharmacogn Phytochem. 2:10–14.
   Google Scholar
• Imam S, Azhar I, Hasan MM, Ali MS, Ahmed SW. 2007. Two triterpenes lupanone and lupeol isolated and identified from Tamarindus indica Linn. Pak J Pharm Sci. 20(2):125–127.
   PubMed Web of Science ®Google Scholar
• International Plant Names Index. 2024. Heptapleurum Gaertn. http://www.ipni.org.
   Google Scholar
• Kim DK, Nam IL, Kim JW, Shin TY, Lim JD. 2002. Pentacyclic triterpenoids from Ilex mcropoda. Arch Pharm Res. 25(5):617–620. doi:10.1007/BF02976931.
   Web of Science ®Google Scholar
• La DM, Chau VM, Tran VS, Pham QL, Phan VK, Tran HT, Tran MH, Ninh KB, Le MH. 2013. Prospects of natural bioactive products from Araliaceae Juss. Family in VietNam. The 5-th National Conference on Ecology and Biological Resources, 1152–1158.
   Google Scholar
• Li H, Cai ZZ, Zhu LP, Xu XJ, Chen SR, Yang DP, Zhao ZM. 2015. A new bibenzyl derivative with nuclear factor-kappaB inhibitory activity from Schefflera arboricola (Araliaceae). Nat Prod Res. 29(12):1139–1144. doi:10.1080/14786419.2014.983506.
   PubMed Web of Science ®Google Scholar
• Li YL, But PPH, Ooi VEC. 2005. Antiviral activity and mode of action of caffeoylquinic acids from Schefflera heptaphylla (L.) Frodin. Antiviral Res. 68(1):1–9. doi:10.1016/j.antiviral.2005.06.004.
   PubMed Web of Science ®Google Scholar
• Matsui K, Wirotesangthong M, Thanakijcharoenpath W, Mungmee C, Nishikawa A. 2010. Inhibitory effects of Schefflera leucantha extract on production of allergic mediators by langerhans cells and mast cells. J Investig Allergol Clin Immunol. 20(6):463–468.
   PubMed Web of Science ®Google Scholar
• Nguyen CTS, Vo TH, Pham NKT, Huynh BLC, Ngo TN, Dang VS, Huynh TKC, Bui TD, Nguyen DXK, Phan NM, et al. 2024. Comtrifosides A and B, two new triterpenoid saponins from the leaves of Combretum trifoliatum. Nat Prod Res. 1–8. doi:10.1080/14786419.2024.2332487).
   Web of Science ®Google Scholar
• Nguyen TP, Le TD, Phan NM, Bui TD, Mai DT. 2016a. Triterpene saponins with α-glucosidase inhibition and cytotoxic activity from the leaves of Schefflera sessiliflora. J Asian Nat Prod Res. 18(6):542–549. doi:10.1080/10286020.2015.1121999.
   PubMed Web of Science ®Google Scholar
• Nguyen TP, Le TD, Phan NM, Bui TD, Pham NKT, Do TML, Nguyen DT, Mai DT. 2016b. A new dihydrofurocoumarin from the fruits of Pandanus tectorius Parkinson ex Du Roi. Nat Prod Res. 30:2389–2395.
   PubMed Web of Science ®Google Scholar
• Nguyen TP, Le TVH, Mai DT, Le TD, Phan NM, Bui TD. 2015a. Two new oleanane-type triterpene saponins from the leaves of Schefflera sessiliflora De. P. V. Phytochem Lett. 11:102–105. doi:10.1016/j.phytol.2014.11.020.
   Web of Science ®Google Scholar
• Nguyen TP, Tran TTV, Mai DT, Le TD, Phan NM, Bui TD. 2015b. New C20-gibberellin diterpene from the leaves of Schefflera sessiliflora De P. V. Nat Prod Res. 29(15):1432–1436. doi:10.1080/14786419.2014.1003300.
   PubMed Web of Science ®Google Scholar
• Pancharoen O, Tuntiwachwuttikul P, Taylor WC, Picker K. 1994. Triterpenoid glycosides from Schefflera leucantha. Phytochemistry. 35(4):987–992. doi:10.1016/s0031-9422(00)90653-8.
   PubMed Web of Science ®Google Scholar
• Pham NKT, Nguyen TD, Tran DDC, Ha TD, Tran NMA, Tran DT, Mai DT, Nguyen TP. 2021. Stercufoetin A, new oleanane-type triterpenoid from the leaves of Sterculia foetida L. Nat Prod Res. 35(7):1226–1231. doi:10.1080/14786419.2019.1644508.
   PubMed Web of Science ®Google Scholar
• Shai LJ, Magano SR, Lebelo SL, Mogale AM. 2011. Inhibitory effects of five medicinal plants on rat alpha-glucosidase: comparison with their effects on yeast alpha-glucosidase. J Med Plants Res. 5:2863–2867.
   Google Scholar
• Sharief MU, Kumar S, Diwakar PG, Sharma TVRS. 2005. Traditional phytotherapy among Karens of Middle Andaman. Indian J Tradit Know. 4:429–436.
   Google Scholar
• Siddiqui S, Hafeez F, Begum S, Siddiqui SB. 1988. Oleanderol, a new pentacyclic triterpene from the leaves of Nerium oleander. J Nat Prod. 51(2):229–233. doi:10.1021/np50056a006.
   Web of Science ®Google Scholar
• Srivastava SK. 1992. A new triterpenic acid from Schefflera impressa. J Nat Prod. 55(3):298–302. doi:10.1021/np50081a004.
   Web of Science ®Google Scholar
• Tran VS, Peter-Katalinic J, Günter A. 1991. A bidesmosidic triterpenoid saponin from Schefflera octaphylla. Phytochemistry. 30:3717–3720.
   PubMed Web of Science ®Google Scholar
• Wanas AS, Matsunami K, Otsuka H, Desoukey SY, Fouad MA, Kamel MS. 2010. Triterpene glycosides and glucosyl esters, and a triterpene from the leaves of Schefflera actinophylla. Chem Pharm Bull (Tokyo). 58(12):1596–1601. doi:10.1248/cpb.58.1596.
   PubMed Web of Science ®Google Scholar
• Wang Y., Khan F. A., Siddiqui M., Aamer M., Lu C., Rahman A., Wahab A. T. and Choudhary M. I. (2021). The genus Schefflera: a review of traditional uses, phytochemistry and pharmacology. J Ethnopharmacol. 279:113675. doi:10.1016/j.jep.2020.113675.
   PubMed Web of Science ®Google Scholar
• Wang Y, Liang D, Khan FA, Zhang CL, Liu YF, Chen RY, Choudhary MI, Yu DQ. 2020. Chemical constituents from Schefflera leucantha R.Vig. (Araliaceae). Biochem Syst Ecol. 91:104076. doi:10.1016/j.bse.2020.104076.
   Web of Science ®Google Scholar
• Wang Y, Liu YF, Zhang CL, Liang D, Luo H, Hao ZY, Chen RY, Yu DQ. 2016. Four new triterpenoid saponins isolated from Schefflera kwangsiensis and their inhibitory activities against FBPase1. Phytochem Lett. 15:204–209. doi:10.1016/j.phytol.2016.01.007.
   Web of Science ®Google Scholar
• Wang Y, Wang L, Wang WJ, Zhang XQ, Tian HY, Zhang QW, Li YL, Ye WC. 2014. New triterpenoid saponins from the aerial parts of Schefflera kwangsiensis. Carbohydr Res. 385:65–71. doi:10.1016/j.carres.2013.07.016.
   PubMed Web of Science ®Google Scholar
• Wang Y, Zhang CL, Liu YF, Liang D, Shi GR, Wang X, Chen RY, Wang FZ, Yu DQ. 2019. Sesquiterpenes and nor sesquiterpenes from Schefflera leucantha R.Vig. (Araliaceae). Biochem Syst Ecol. 83:7–9. doi:10.1016/j.bse.2018.12.007.
   Web of Science ®Google Scholar
• World Checklist of Vascular Plants. 2024. Heptapleurum Gaertn. https://powo.science.kew.org.
   Google Scholar
• World Flora Online. 2024. Heptapleurum Gaertn. [accessed 2024 May 27]. http://www.worldfloraonline.org/taxon/wfo-4000017517.
   Google Scholar
• Wu C, Duan YH, Li MM, Tang W, Wu X, Wang GC, Ye WC, Zhou GX, Li YL. 2013. Triterpenoid saponins from the stem barks of Schefflera heptaphylla. Planta Med. 79(14):1348–1355. doi:10.1055/s-0033-1350674.
   PubMed Web of Science ®Google Scholar