277
Views
0
CrossRef citations to date
0
Altmetric
Review

Radioimmunotherapy for the treatment of infectious diseases: a comprehensive update

&
Pages 365-374 | Received 14 Nov 2022, Accepted 21 Feb 2023, Published online: 02 Mar 2023

References

  • Aerts A. Leprosy: the world’s oldest human-rights issue. Nature. 2019;567(30):30.
  • https://www.who.int/health-topics/smallpox#tab=tab_1 Accessed on Oct 17 at 4:23 PM
  • Levy SB, Bonnie M. Antibacterial resistance worldwide: causes, challenges and responses. Nat Med. 2004;10(12S):S122–9.
  • van Dijk B, Lemans JVC, Hoogendoorn RM, et al. van der Wal BCH. Treating infections with ionizing radiation: a historical perspective and emerging techniques. Antimicrob Resist Infect Control. 2020 Jul 31;9(1):121.
  • Sharkey RM, Goldenberg DM. Cancer radioimmunotherapy. Immunotherapy. 2011 3;Mar(3):349–370.
  • Dadachova E, Nakouzi A, Bryan RA, et al. Ionizing radiation delivered by specific antibody is therapeutic against a fungal infection. Proc Natl Acad Sci U S A. 2003 Sep 16;100(19):10942–10947.
  • Martinez LR, Bryan RA, Apostolidis C, et al. Antibody-guided alpha radiation effectively damages fungal biofilms. Antimicrob Agents Chemother. 2006;50(6):2132–2136.
  • Helal M, Dadachova E. Radioimmunotherapy as a novel approach in HIV, bacterial, and fungal infectious diseases. Cancer Biother Radiopharm. 2018;33(8):330–335.
  • Dadachova E. Future Vistas in Alpha Therapy of Infectious Diseases. J Med Imaging Radiat Sci. 2019 Dec;50(4 Suppl 1):S49–S52.
  • Srikanta D, Santiago-Tirado FH, Doering TL. Cryptococcus neoformans: historical curiosity to modern pathogen. Yeast. 2014 Feb;31(2):47–60.
  • Busse O. Uber parasitare Zelleinschlusse und ihre Zuchtung. Centralbl Bakt Parasit. 1894;16:175–180.
  • Sanfelice F. Contributo alla morfologia e biologia dei blastomiceti che si sviluppano nei succhi de alcuni frutti. Ann Ist Ig R Univ Roma. 1894;4:463–469.
  • Barnett JA. A history of research on yeasts 14: medical yeasts part 2, Cryptococcus neoformans. Yeast. 2010;27:875–904.
  • Dadachova E, Casadevall A. Radioimmunotherapy of infectious diseases. Semin Nucl Med. 2009 Mar;39(2):146–153.
  • Alspaugh JA. Virulence mechanisms and Cryptococcus neoformans pathogenesis. Fungal Genet Biol. 2015May;78:55–58.
  • Zhao Y, Lin X. Cryptococcus neoformans: Sex, morphogenesis, and virulence. Infect Genet Evol. 2021Apr;89:104731.
  • Alanio A. Dormancy in Cryptococcus neoformans: 60 years of accumulating evidence. J Clin Invest. 2020 Jul 1;130(7):3353–3360.
  • Thompson GR 3rd, Wiederhold NP, Najvar LK, et al. A murine model of Cryptococcus gattii meningoencephalitis. J Antimicrob Chemother. 2012 Jun;67(6):1432–1438.
  • Helal M, Allen KJH, van Dijk B, et al. Radioimmunotherapy of blastomycosis in a mouse model with a (1-3)-β-glucans targeting antibody. Front Microbiol. 2020;11:147.
  • Helal M, Allen KJH, Burgess H, et al. Safety evaluation of an alpha-emitter bismuth-213 labeled antibody to (1→3)-β-Glucan in healthy dogs as a prelude for a trial in companion dogs with invasive fungal infections. Molecules. 2020 Aug 8;25(16):3604.
  • Bryan RA, Guimaraes AJ, Hopcraft S, et al. Toward developing a universal treatment for fungal disease using radioimmunotherapy targeting common fungal antigens. Mycopathologia. 2012;173:463–471.
  • Qureshi A, Niazi JH. Biosensors for detecting viral and bacterial infections using host biomarkers: a review. Analyst. 2021 Jan 7;145(24):7825–7848.
  • Rao SS, Mohan KV, Atreya CD. Detection technologies for Bacillus anthracis: prospects and challenges. J Microbiol Methods. 2010 Jul;82(1):1–10.
  • Smith H, Keppie J. Observation on experimental anthrax: demonstration of a specific lethal factor produced in vivo by Bacillus anthracis. Nature. 1954;173(4410:869–870.
  • Rivera J, Nakouzi AS, Morgenstern A, et al. Radiolabeled antibodies to Bacillus anthracis toxins are bactericidal and partially therapeutic in experimental murine anthrax. Antimicrob Agents Chemother. 2009 Nov;53(11):4860–4868.
  • Rivera J, Morgenstern A, Bruchertseifer F, et al. Microbicidal power of alpha radiation in sterilizing germinating Bacillus anthracis spores. Antimicrob Agents Chemother. 2014;58(3):1813–1815.
  • Parvizi J, Jacovides C, Zmistowski B, et al. Definition of periprosthetic joint infection: Is there a consensus? Clinical Orthopaedics and Related Research. 2011;3022–3030. 10.1007/s11999-011-1971-2.
  • van Dijk B, Allen KJH, Helal M, et al. Radioimmunotherapy of methicillin-resistant Staphylococcus aureus in planktonic state and biofilms. PLoS One. 2020 May 14;15(5):e0233086.
  • de Vor VD, van Dijk B, van Kessel K, et al. Human monoclonal antibodies against Staphylococcus aureus surface antigens recognize in vitro and in vivo biofilm. eLife. 2022;11:ed67301.
  • Dieleman JL, Haakenstad A, Micah A,Global Burden of Disease Health Financing Collaborator Network. Spending on health and HIV/AIDS: domestic health spending and development assistance in 188 countries, 1995-2015. Lancet. 2018 May 5; 391: 10132. 1799–1829.
  • Shiels MS, Engels EA. Evolving epidemiology of HIV-associated malignancies. Curr Opin HIV AIDS. 2017 Jan;12(1):6–11.
  • Katlama C, Deeks SG, Autran B, et al. Barriers to a cure for HIV: new ways to target and eradicate HIV-1 reservoirs. Lancet. 2013;381:2109–2117.
  • Sillman B, Woldstad C, Mcmillan J, et al. Neuropathogenesis of human immunodeficiency virus infection. Handb Clin Neurol. 2018;152:21–40.
  • Tsukrov D, McFarren A, Morgenstern A, et al. Combination of antiretroviral drugs and radioimmunotherapy specifically kills infected cells from HIV-infected individuals. Front Med (Lausanne). 2016 Sep 26;3: 41.
  • McFarren A, Lopez L, Williams DW, et al. A fully human antibody to gp41 selectively eliminates HIV-infected cells that transmigrated across a model human blood brain barrier. AIDS. 2016 Feb 20;30(4):563–572.
  • Garg R, Mills K, Allen KJH, et al. Comparison of various radioactive payloads for a human monoclonal antibody to glycoprotein 41 for elimination of HIV-infected cells. Nucl Med Biol. 2020;82-83:80–88.
  • Macklis RM. How and why does radioimmunotherapy works? Int J Radiation Oncology Biol Phys. 2004;59:1269–1271.
  • Bryan RA, Huang X, Morgenstern A, et al. Dadachova Radio-fungicidal effects of external gamma radiation and antibody-targeted beta and alpha radiation on Cryptococcus neoformans. Antimicrob Agents Chemother. 2008;52:2232–2235.
  • Dadachova E, Burns T, Bryan RA, et al. Feasibility of radioimmunotherapy of experimental pneumococcal infection. Antimicrob Agents Chemother. 2004;48:1624–1629.
  • Dadachova E, Patel MC, Toussi S, et al. Targeted killing of virally infected cells by radiolabeled antibodies to viral proteins. PLoS Med. 2006;3:e427.
  • Jurcic JG. Targeted Alpha-Particle Therapy for Hematologic Malignancies. Semin Nucl Med. 2020;50:152–161.
  • Rosenblat TL, McDevitt MR, Carrasquillo JA, et al. Treatment of patients with acute myeloid leukemia with the targeted alpha-particle nanogenerator actinium-225-lintuzumab. Clin Cancer Res. 2022;28:2030–2037.
  • Jurcic JG. Ab therapy of AML: Native anti-CD33 Ab and drug conjugates. Cytotherapy. 2008;10:7–12.
  • Lindén O, Bates AT, Cunningham D, et al. 227Th-labeled anti-CD22 antibody (BAY 1862864) in relapsed/refractory CD22-positive non-Hodgkin lymphoma: a first-in-human, phase I study. Cancer Biother Radiopharm. 2021 Oct;36(8):672–681.
  • Sgouros G, Bodei L, McDevitt MR, et al. Radiopharmaceutical therapy in cancer: clinical advances and challenges. Nat Rev Drug Discov. 2020 Sep;19(9):589–608.
  • Neumaier F, Zlatopolskiy BD, Neumaier B. Zlatopolskiy BD and Neumaier B. Nuclear medicine in times of COVID-19: how radiopharmaceuticals could help to fight the current and future pandemics. Pharmaceutics. 2020;12:1247.
  • Sharma R, Kumar P, Rauf A, et al. Conte-junior CA mucormycosis in the COVID-19 environment: a multifaceted complication. Front Cell Infect Microbiol. 2022 Jul 18;12: 937481.
  • Akhtar N, Khurshid Wani A, Kant Tripathi S, et al. Amin-Ul Mannan M The role of SARS-CoV-2 immunosuppression and the therapy used to manage COVID-19 disease in the emergence of opportunistic fungal infections: A review. Curr Res Biotechnol. 2022;4:337–349.
  • Dadachova E, Berman JW. Non-invasive nuclear imaging for localization of viral reservoirs. Nat Methods. 2015 May;12(5):399–400.
  • Schwenck J, Maurer A, Beziere N, et al. Antibody-guided molecular imaging of aspergillus lung infections in leukemia patients. J Nucl Med. 2022Jul;21:jnumed.121.263251.
  • Beckford-Vera DR, Flavell RR, Seo Y, et al. First-in-human immunoPET imaging of HIV-1 infection using 89Zr-labeled VRC01 broadly neutralizing antibody. Nat Commun. 2022 Mar 9;13(1):1219.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.