1,014
Views
28
CrossRef citations to date
0
Altmetric
Original Articles

Labeled Nucleoside Triphosphates with Reversibly Terminating Aminoalkoxyl Groups

, , , , , , , , & show all
Pages 879-895 | Received 08 Apr 2010, Accepted 27 Oct 2010, Published online: 01 Dec 2010

REFERENCES

  • Metzker , M. L. 2005 . Emerging technologies in DNA sequencing . Genome Res. , 15 : 1767 – 1776 .
  • Fuller , C. W. , Middendorf , L. R. , Benner , S. A. , Church , G. M. , Harris , T. , Huang , X. , Jovanovich , S. B. , Nelson , J. R. , Schloss , J. A. , Schwartz , D. C. and Vezenov , D. V. 2009 . The challenges of sequencing by synthesis . Nature Biotechnology , 27 : 1013 – 1023 .
  • Hiatt , A. C. Compositions for enzyme catalyzed template-independent creation of phosphodiester bonds using protected nucleotides . 2001 . U.S. Patent No. 6232465
  • Ruparel , H. , Bi , L. R. , Li , Z. M. , Bai , X. P. , Kim , D. H. , Turro , N. J. and Ju , J. Y. 2005 . Design and synthesis of a 3′-O-allyl photocleavable fluorescent nucleotide as a reversible terminator for DNA sequencing by synthesis . Proc. Natl. Acad. Sci. USA , 102 : 5932 – 5937 .
  • Ju , J. Y. , Kim , D. H. , Bi , L. R. , Meng , Q. L. , Bai , X. P. , Li , Z. M. , Li , X. X. , Marma , M. S. , Shi , S. , Wu , J. , Edwards , J. R. , Romu , A. and Turro , N. J. 2006 . Four-color DNA sequencing by synthesis using cleavable fluorescent nucleotide reversible terminators . Proc. Natl. Acad. Sci. USA , 103 : 19635 – 196340 .
  • Metzker , M. L. , Raghavachari , R. , Richards , S. , Jacutin , S. E. , Civitello , A. , Burgess , K. and Gibbs , R. A. 1994 . Termination of DNA synthesis by novel 3′-modified deoxyribonucleoside 5′-triphosphates . Nucleic Acids Res. , 22 : 4259 – 4267 .
  • Guo , J. , Xu , N. , Li , Z. M. , Zhang , S. L. , Wu , J. , Kim , D. H. , Marma , M. S. , Meng , Q. L. , Cao , H. Y. , Li , X. X. , Shi , S. D. , Yu , L. , Kalachikov , S. , Russo , J. J. , Turro , N. J. and Ju , J. Y. 2008 . Four-color DNA sequencing with 3′-O-modified nucleotide reversible terminators and chemically cleavable fluorescent dideoxynucleotides . Proc. Natl. Acad. Sci. USA , 105 : 9145 – 9150 .
  • Ju , J. Y. , Kim , D. H. , Guo , J. , Meng , Q. L. , Li , Z. M. and Cao , H. Y. 2008 . “ DNA sequencing with non-fluorescent nucleotide reversible terminators and cleavable label modified nucleotide terminators ” . PCT Int. Appl. Publ. WO2009054922
  • Wu , W. , Stupi , B. P. , Litosh , V. A. , Mansouri , D. , Farley , D. , Morris , S. , Metzker , S. and Metzker , M. L. 2007 . Termination of DNA synthesis by N6-alkylated, not 3′-O-alkylated, photocleavable 2′-deoxyadenosine triphosphates . Nucleic Acids Res. , 35 : 6339 – 6449 .
  • Benner , S. A. Method for sequencing DNA and RNA by synthesis . 2009 . U.S. Patent No. 7544794
  • Chen , F. , Gaucher , E. A. , Leal , N. A. , Hutter , D. , Havemann , S. A. , Govindarajan , S. , Ortlund , E. A. and Benner , S. A. 2010 . Reconstructed Evolutionary Adaptive Paths (REAP) give polymerases accepting reversible terminators for sequencing and SNP detection . Proc. Natl. Acad. Sci. USA , 107 : 1948 – 1953 .
  • Kondo , K. , Ogiku , T. and Inoue , I. 1985 . Synthesis of 5′(3′)-O-amino nucleosides . Nucleic Acids Res. Symp. Ser. , 16 : 93 – 96 .
  • Burgess , K. , Gibbs , R. A. , Metzker , M. L. and Raghavachari , R. 1994 . Synthesis of an oxyamide linked nucleotide dimer and incorporation into antisense oligonucleotide sequences . J. Chem. Soc. Chem. Commun. , 8 : 915 – 916 .
  • Ludwig , J. and Eckstein , F. 1989 . Rapid and efficient synthesis of nucleoside 5′-O-(1-thiotriphosphates), 5′-triphosphates and 2′,3′-cyclophosphorothioates using 2-chloro-4H-1,3,2-benzodioxaphosphorin-4-one . J. Org. Chem. , 54 : 631 – 635 .
  • Tasara , T. , Angerer , B. , Damond , M. , Winter , H. , Doerhoefer , S. , Huebscher , U. and Amacker , M. 2003 . Incorporation of reporter molecule-labeled nucleotides by DNA polymerases. II. High-density labeling of natural DNA . Nucl. Acids Res. , 31 : 2636 – 2646 .
  • Horlacher , J. , Hottiger , M. , Podust , V. N. , Huebscher , U. and Benner , S. A. 1995 . Recognition by viral and cellular DNA polymerases of nucleosides bearing bases with nonstandard hydrogen bonding patterns . Proc. Natl. Acad. Sci. USA , 92 : 6329 – 6333 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.