Modulation of HIV-1 Integrase Activity by Single-Stranded Oligonucleotides and their Conjugates with Eosin

REFERENCES

• Engelman , A. and Craigie , R. 1995 . Efficient magnesium-dependent human immunodeficiency virus type 1 integrase activity . J. Virol. , 69 : 5908 – 5911 .
   PubMed Web of Science ®Google Scholar
• Esposito , D. and Craigie , R. 1998 . Sequence specificity of viral end DNA binding by HIV-1 integrase reveals critical regions for protein-DNA interaction . EMBO J. , 17 : 5832 – 5843 .
   PubMed Web of Science ®Google Scholar
• Agapkina , J. , Smolov , M. , Barbe , S. , Zubin , E. , Zatsepin , T. , Deprez , E. , Le Bret , M. , Mouscadet , J.-F. and Gottikh , M. 2006 . Probing of HIV-1 integrase-DNA interactions using novel analogs of viral DNA . J. Biol. Chem , 281 : 11530 – 11540 .
   PubMed Web of Science ®Google Scholar
• Hare , S. , Gupta , S. S. , Valkov , E. , Engelman , A. and Cherepanov , P. 2010 . Retroviral intasome assembly and inhibition of DNA strand transfer . Nature , 464 : 232 – 236 .
   PubMed Web of Science ®Google Scholar
• Leh , H. , Brodin , P. , Bischerour , J. , Deprez , E. , Tauc , P. , Brochon , J. C. , LeCam , E. , Coulaud , D. , Auclair , C. and Mouscadet , J. F. 2000 . Determinants of Mg2+-dependent activities of recombinant human immunodeficiency virus type 1 integrase . Biochemistry , 39 : 9285 – 9294 .
   PubMed Web of Science ®Google Scholar
• Zheng , R. , Jenkins , T. M. and Craigie , R. 1996 . Zinc folds the N-terminal domain of HIV-1 integrase, promotes multimerization, and enhances catalytic activity . Proc. Natl. Acad. Sci. USA. , 93 : 13659 – 13664 .
   PubMed Web of Science ®Google Scholar
• Lee , S. P. , Xiao , J. , Knutson , J. R. , Lewis , M. S. and Han , M. K. 1997 . Zn2+ promotes the self-association of human immunodeficiency virus type-1 integrase in vitro . Biochemistry , 36 : 173 – 180 .
   PubMed Web of Science ®Google Scholar
• Deprez , E. , Tauc , P. , Leh , H. , Mouscadet , J.-F. , Auclair , C. and Brochon , J.-C. 2000 . Oligomeric states of the HIV-1 integrase as measured by time-resolved fluorescence anisotropy . Biochemistry , 39 : 9275 – 9284 .
   PubMed Web of Science ®Google Scholar
• Baranova , S. , Tuzikov , F. V. , Zakharova , O. D. , Tuzikova , N. A. , Calmels , C. , Litvak , S. , Tarrago-Litvak , L. , Parissi , V. and Nevinsky , G. A. 2007 . Small-angle X-ray characterization of the nucleoprotein complexes resulting from DNA-induced oligomerization of HIV-1 integrase . Nucleic Acids Res. , 35 : 975 – 987 .
   PubMed Web of Science ®Google Scholar
• Caumont , A. , Jamieson , G. , de Soultrait , V. R. , Parissi , V. , Fournier , M. , Zakharova , O. D. , Bayandin , R. , Litvak , S. , Tarrago-Litvak , L. and Nevinsky , G. A. 1999 . High affinity interaction of HIV-1 integrase with specific and non-specific single-stranded short oligonucleotides . FEBS Lett. , 455 : 154 – 158 .
   PubMed Web of Science ®Google Scholar
• Pinskaya , M. , Romanova , E. , Volkov , E. , Deprez , E. , Leh , H. , Brochon , J. C. , Mouscadet , J. F. and Gottikh , M. 2004 . HIV-1 integrase complexes with DNA dissociate in the presence of short oligonucleotides conjugated to acridine . Biochemistry , 43 : 8735 – 8743 .
   PubMed Web of Science ®Google Scholar
• Prikazchikova , T. A. , Volkov , E. , Zubin , E. M. , Romanova , E. and Gottikh , M. 2007 . Inhibition of HIV-1 integrase by modified oligonucleotides: optimization of the inhibitor structure . Mol. Biol. (Moscow) , 41 : 130 – 138 .
   PubMed Web of Science ®Google Scholar
• Michel , F. , Crucifix , C. , Granger , F. , Eiler , S. , Mouscadet , J. F. , Korolev , S. , Agapkina , J. , Ziganshin , R. , Gottikh , M. , Nazabal , A. , Emiliani , S. , Benarous , R. , Moras , D. , Schultz , P. and Ruff , M. 2009 . Structural basis for HIV-1 DNA integration in the human genome, role of the LEDGF/P75 cofactor . EMBO J. , 28 : 980 – 991 .
   PubMed Web of Science ®Google Scholar
• Smolov , M. , Gottikh , M. , Tashlitskii , V. , Korolev , S. , Demidyuk , I. , Brochon , J. C. , Mouscadet , J.-F. and Deprez , E. 2006 . Kinetic study of the HIV-1 DNA 3′-end processing: single turnover properties of integrase . FEBS J. , 273 : 1137 – 1151 .
   PubMed Web of Science ®Google Scholar
• Varfolomeev , S. D. and Gurevich , K. G. 1999 . Biokinetics , Moscow : Fair-press .
   Google Scholar
• Lecellier , C. H. and Saib , A. 2000 . Foamy viruses: between retroviruses and pararetroviruses . Virology , 271 : 1 – 8 .
   PubMed Web of Science ®Google Scholar
• Valkov , E. , Gupta , S. S. , Hare , S. , Helander , A. , Roversi , P. , McClure , M. and Cherepanov , P. 2009 . Functional and structural characterization of the integrase from the prototype foamy virus . Nucleic Acids Res , 37 : 243 – 255 .
   PubMed Web of Science ®Google Scholar
• Carayon , K. , Leh , H. , Henry , E. , Simon , F. , Mouscadet , J. F. and Deprez , E. 2010 . A cooperative and specific DNA-binding mode of HIV-1 integrase depends on the nature of the metallic cofactor and involves the zinc-containing N-terminal domain . Nucleic Acids Res , 38 : 3692 – 3708 .
   PubMed Web of Science ®Google Scholar