Advanced search
Publication Cover
Nucleosides, Nucleotides & Nucleic Acids Volume 39, 2020 - Issue 10-12
Submit an article Journal homepage
292
Views
2
CrossRef citations to date
0
Altmetric
Conference Proceedings

Xanthine oxidoreductase knockout mice with high HPRT activity were not rescued by NAD+ replenishment

Makoto HosoyamadaDepartment of Human Physiology and Pathology, Faculty of Pharma-Science, Teikyo University, Tokyo, Japan; Correspondence[email protected]
ORCID Iconhttp://orcid.org/0000-0002-6584-3055View further author information
ORCID Icon,
Naoko H. TomiokaDepartment of Human Physiology and Pathology, Faculty of Pharma-Science, Teikyo University, Tokyo, Japan; View further author information
,
Toshio OhtsuboDepartment of Internal Medicine (Hypertension), Fukuoka Red Cross Hospital, Fukuoka, Japan; View further author information
&
Kimiyoshi IchidaDepartment of Pathophysiology, Tokyo University of Pharmacy and Life Sciences, Tokyo, JapanView further author information
Pages 1465-1473 | Received 16 Dec 2019, Accepted 28 Jan 2020, Published online: 04 Mar 2020

References

  • Wu, X.; Wakamiya, M.; Vaishnav, S.; Geske, R.; Montgomery, C.; Jones, P.; Bradley, A.; Caskey, C. T. Hyperuricemia and Urate Nephropathy in Urate Oxidase-Deficient Mice. Proc. Natl. Acad. Sci. USA 1994, 91, 742–746. DOI: 10.1073/pnas.91.2.742.
  • Ohtsubo, T.; Rovira, I. I.; Starost, M. F.; Liu, C.; Finkel, T. Xanthine Oxidoreductase is an Endogenous Regulator of Cyclooxygenase-2. Circ. Res. 2004, 95, 1118–1124. DOI: 10.1161/01.RES.0000149571.96304.36.
  • Wu, C. L.; Melton, D. W. Production of a Model for Lesch-Nyhan Syndrome in Hypoxanthine Phosphoribosyltransferase-Deficient Mice. Nat. Genet. 1993, 3, 235–240. DOI: 10.1038/ng0393-235.
  • Hosoyamada, M.; Tsurumi, Y.; Hirano, H.; Tomioka, N. H.; Sekine, Y.; Morisaki, T.; Uchida, S. Urat1-Uox Double Knockout Mice Are Experimental Animal Models of Renal Hypouricemia and Exercise-Induced Acute Kidney Injury. Nucleosides Nucleotides Nucleic Acids 2016, 35, 543–549. DOI: 10.1080/15257770.2016.1143559.
  • Tax, W. J.; Veerkamp, J. H.; Trijbels, J. M. Activity of Purine Phosphoribosyltransferases and of Two Enzymes of Pyrimidine Biosynthesis in Erythrocytes of Ten Mammalian Species. Comp. Biochem. Physiol. B 1976, 54, 209–212. DOI: 10.1016/0305-0491(76)90144-9.
  • Xu, P.; LaVallee, P.; Hoidal, J. R. Repressed Expression of the Human Xanthine Oxidoreductase Gene. E-Box and TATA-like Elements Restrict Ground State Transcriptional Activity. J. Biol. Chem. 2000, 275, 5918–5926. DOI: 10.1074/jbc.275.8.5918.
  • Takada, T.; Mita, A.; Maeno, A.; Sakai, T.; Shitara, H.; Kikkawa, Y.; Moriwaki, K.; Yonekawa, H.; Shiroishi, T. Mouse Inter-Subspecific Consomic Strains for Genetic Dissection of Quantitative Complex Traits. Genome Res. 2008, 18, 500–508. DOI: 10.1101/gr.7175308.
  • Hosoyamada, M.; Takiue, Y.; Morisaki, H.; Cheng, J.; Ikawa, M.; Okabe, M.; Morisaki, T.; Ichida, K.; Hosoya, T.; Shibasaki, T.; et al. Establishment and Analysis of SLC22A12 (URAT1) Knockout Mouse. Nucleosides Nucleotides Nucleic Acids 2010, 29, 314–320. DOI: 10.1080/15257771003738634.
  • Preiss, J.; Handler, P. Enzymatic Synthesis of Nicotinamide Mononucleotide. J. Biol. Chem. 1957, 225, 759–770.
  • Griffith, D. A.; Jarvis, S. M. Characterization of a Sodium-Dependent Concentrative Nucleobase-Transport System in guinea-Pig Kidney Cortex Brush-Border Membrane Vesicles. Biochem. J. 1994, 303, 901–905. DOI: 10.1042/bj3030901.
  • Perico, L.; Benigni, A. The iNADequacy of Renal Cell Metabolism: modulating NAD(+) Biosynthetic Pathways to Forestall Kidney Diseases. Kidney Int. 2019, 96, 264–267. DOI: 10.1016/j.kint.2019.03.012.
  • Yamamoto, S.; Inoue, K.; Murata, T.; Kamigaso, S.; Yasujima, T.; Maeda, J-y.; Yoshida, Y.; Ohta, K-y.; Yuasa, H. Identification and Functional Characterization of the First Nucleobase Transporter in Mammals: implication in the Species Difference in the Intestinal Absorption Mechanism of Nucleobases and Their Analogs between Higher Primates and Other Mammals. J. Biol. Chem. 2010, 285, 6522–6531. DOI: 10.1074/jbc.M109.032961.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.