References
- Wordsworth, B. P.; Cohen, C. J.; Davidson, C.; Vecellio, M. Perspectives on the Genetic Associations of Ankylosing Spondylitis. Front. Immunol. 2021, 12, 603726. DOI: https://doi.org/10.3389/fimmu.2021.603726.
- Zheng, X.; Li, Q.; Li, X.; Zhang, Y.; Wu, X.; Wei, Q.; Cao, S.; Yang, M.; Lin, Z.; Liao, Z.; et al. Analysis of 47 Non-MHC Ankylosing Spondylitis Susceptibility Loci regarding Associated Variants across Whites and Han Chinese. J. Rheumatol. 2020, 47, 674–681. DOI: https://doi.org/10.3899/jrheum.190184.
- Brown, M. A.; Kennedy, L. G.; Darke, C.; Gibson, K.; Pile, K. D.; Shatford, J. L.; Taylor, A.; Calin, A.; Wordsworth, B. P. The Effect of HLA-DR Genes on Susceptibility to and Severity of Ankylosing Spondylitis. Arthritis Rheum 2004, 41, 460–465. DOI: https://doi.org/10.1002/1529-0131(199803)41:3 < 460::AID-ART12 > 3.0.CO;2-X.
- Smith, J. A. Update on Ankylosing Spondylitis: current Concepts in Pathogenesis. Curr Allergy Asthma Rep . 2015, 15, 489. DOI: https://doi.org/10.1007/s11882-014-0489-6.
- Burton, P. R.; Clayton, D. G.; Cardon, L. R.; Craddock, N.; Deloukas, P.; Duncanson, A.; Kwiatkowski, D. P.; McCarthy, M. I.; Ouwehand, W. H.; Samani, N. J.; Breast Cancer Susceptibility Collaboration (UK).; et al. Association Scan of 14,500 Nonsynonymous SNPs in Four Diseases Identifies Autoimmunity variants. Nat. Genet. 2007, 39, 1329–1337. DOI: https://doi.org/10.1038/ng.2007.17.
- Davidson, S. I.; Wu, X.; Liu, Y.; Wei, M.; Danoy, P. A.; Thomas, G.; Cai, Q.; Sun, L.; Duncan, E.; Wang, N.; et al. Association of ERAP1, but Not IL23R, with Ankylosing Spondylitis in a Han Chinese Population. Arthritis Rheum. 2009, 60, 3263–3268. DOI: https://doi.org/10.1002/art.24933.
- Harvey, D.; Pointon, J. J.; Evans, D. M.; Karaderi, T.; Farrar, C.; Appleton, L. H.; Sturrock, R. D.; Stone, M. A.; Oppermann, U.; Brown, M. A.; Wordsworth, B. P. Investigating the Genetic Association between ERAP1 and Ankylosing Spondylitis. Human Molecul. Genet. 2009, 18, 4204–4212. DOI: https://doi.org/10.1093/hmg/ddp371.
- Rastall, D. P. W.; Aldhamen, Y. A.; Seregin, S. S.; Godbehere, S.; Amalfitano, A. ERAP1 Functions Override the Intrinsic Selection of Specific Antigens as Immunodominant Peptides, Thereby Altering the Potency of Antigen-Specific Cytolytic and Effector Memory T-Cell Responses. Int. Immunol. 2014, 26, 685–695. DOI: https://doi.org/10.1093/intimm/dxu078.
- Tanioka, T.; Hattori, A.; Masuda, S.; Nomura, Y.; Nakayama, H.; Mizutani, S.; Tsujimoto, M. Human Leukocyte-Derived Arginine Aminopeptidase. The Third Member of the Oxytocinase Subfamily of Aminopeptidases. J. Biol. Chem. 2003, 278, 32275–32283. DOI: https://doi.org/10.1074/jbc.M305076200.
- Choi, C. B.; Kim, T. H.; Jun, J. B.; Lee, H. S.; Shim, S. C.; Lee, B.; Pope, A.; Uddin, M.; Rahman, P.; Inman, R. D. ARTS1 Polymorphisms Are Associated with Ankylosing Spondylitis in Koreans. Ann. Rheum. Dis. 2010, 69, 582–584. DOI: https://doi.org/10.1136/ard.2008.105296.
- Bang, S. Y.; Kim, T. H.; Lee, B.; Kwon, E.; Choi, S. H.; Lee, K. S.; Shim, S. C.; Pope, A.; Rahman, P.; Reveille, J. D.; Inman, R. D. Genetic Studies of Ankylosing Spondylitis in Koreans Confirm Associations with ERAP1 and 2p15 Reported in White Patients. J. Rheumatol. 2011, 38, 322–324. DOI: https://doi.org/10.3899/jrheum.100652.
- Mahmoudi, M.; Jamshidi, A. R.; Amirzargar, A. A.; Farhadi, E.; Nourijelyani, K.; Fallahi, S.; Oraei, M.; Noori, S.; Nicknam, M. H. Association between Endoplasmic Reticulum Aminopeptidase-1 (ERAP-1) and Susceptibility to Ankylosing Spondylitis in Iran. Iran. J. Allergy. Asthma. Immunol. 2012, 11, 294–300. DOI: https://doi.org/10.1011.04/ijaai.294300.
- Lee, Y. H.; Choi, S. J.; Ji, J. D.; Song, G. G. Associations between ERAP1 Polymorphisms and Ankylosing Spondylitis Susceptibility: A Meta-Analysis. Inflamm. Res. 2011, 60, 999–1003. DOI: https://doi.org/10.1007/s00011-011-0374-x.
- Chen, R.; Yao, L.; Meng, T.; Xu, W. The Association between Seven ERAP1 Polymorphisms and Ankylosing Spondylitis Susceptibility: A Meta-Analysis Involving 8,530 Cases and 12,449 Controls. Rheumatol. Int. 2012, 32, 909–914. DOI: https://doi.org/10.1007/s00296-010-1712-y.
- Cai, G.; Xin, L.; Wang, L.; Fan, D.; Liu, L.; Hu, Y.; Ding, N.; Xu, S.; Xia, G.; Jin, X.; et al. Associations between ERAP1 Polymorphisms and Ankylosing Spondylitis Susceptibility: An Updated Meta-Analysis. Mod. Rheumatol. 2015, 25, 453–461. DOI: https://doi.org/10.3109/14397595.2014.973658.
- Gao, S.; Xu, T.; Liang, W.; Xun, C.; Deng, Q.; Guo, H.; Sheng, W. Association of rs27044 and rs30187 Polymorphisms in Endoplasmic Reticulum Aminopeptidase 1 Gene and Ankylosing Spondylitis Susceptibility: A Meta-Analysis. Int. J. Rheum. Dis. 2020, 23, 499–510. DOI: https://doi.org/10.1111/1756-185X.13795.
- Jiang, Y.; Ren, Y.; Zhou, D.; Xu, Y. Associations between ERAP1 Polymorphisms and Susceptibility to Ankylosing Spondylitis: A Meta-Analysis of East Asian Population. Medicine 2018, 97, e13263. DOI: https://doi.org/10.1097/MD.0000000000013263.
- Hu, N.; Liu, D.; Zhao, N.; Wang, X.; Bai, Y.; Sun, H. Lack of Association between TNF Polymorphism and Ankylosing Spondylitis Susceptibility in HLA-B27-Positive Population: A Meta-Analysis. Eur. Spine J. 2021, 30, 2401–2408. DOI: https://doi.org/10.1007/s00586-021-06892-3.
- Li, B.; Wang, P.; Li, H. The Association between TNF-Alpha Promoter Polymorphisms and Ankylosing Spondylitis: A Meta-Analysis. Clin. Rheumatol. 2010, 29, 983–990. DOI: https://doi.org/10.1007/s10067-010-1499-y.
- Zvyagin, I. V.; Dorodnykh Vy Fau - Mamedov, I. Z.; Mamedov Iz Fau - Staroverov, D. B.; Staroverov Db Fau - Bochkova, A. G.; Bochkova Ag Fau - Rebrikov, D. V.; Rebrikov Dv Fau - Lebedev, Y. B.; Lebedev, Y. B. Association of ERAP1 Allelic Variants with Risk of Ankylosing Spondylitis. 2010
- Bettencourt, B. F.; Rocha, F. L.; Alves, H.; Amorim, R.; Caetano-Lopes, J.; Vieira-Sousa, E.; Pimentel-Santos, F.; Lima, M.; Porto, G.; Branco, J. C.; Fonseca, J. E.; et al. Protective Effect of an ERAP1 Haplotype in Ankylosing Spondylitis: Investigating Non-MHC Genes in HLA-B27-Positive Individuals. Rheumatology (Oxford) 2013, 52, 2168–2176. DOI: https://doi.org/10.1093/rheumatology/ket269.
- Cherciu, M.; Popa, L. O.; Bojinca, M.; Dutescu, M. I.; Bojinca, V.; Bara, C.; Popa, O. M. Functional Variants of ERAP1 Gene Are Associated with HLA-B27 Positive Spondyloarthritis. Tissue Antigens. 2013, 82, 192–196. DOI: https://doi.org/10.1111/tan.12158.
- Paladini, F.; Fiorillo, M. T.; Tedeschi, V.; D’Otolo, V.; Piga, M.; Cauli, A.; Mathieu, A.; Sorrentino, R. The rs75862629 Minor Allele in the Endoplasmic Reticulum Aminopeptidases Intergenic Region Affects Human Leucocyte Antigen B27 Expression and Protects from Ankylosing Spondylitis in Sardinia. Rheumatology (Oxford) 2019, 58, 2315–2324. DOI: https://doi.org/10.1093/rheumatology/kez212.
- Zhang, Z.; Dai, D.; Yu, K.; Yuan, F.; Jin, J.; Ding, L.; Hao, Y.; Liang, F.; Liu, N.; Zhao, X.; et al. Association of HLA-B27 and ERAP1 with Ankylosing Spondylitis Susceptibility in Beijing Han Chinese. Tissue Antigens. 2014, 83, 324–329. DOI: https://doi.org/10.1111/tan.12334.
- Evans, D. M.; Spencer, C. C.; Pointon, J. J.; Su, Z.; Harvey, D.; Kochan, G.; Oppermann, U.; Dilthey, A.; Pirinen, M.; Stone, M. A.; The Australo-Anglo-American Spondyloarthritis Consortium (TASC).; et al. Interaction between ERAP1 and HLA-B27 in Ankylosing Spondylitis Implicates Peptide Handling in the Mechanism for HLA-B27 in Disease Susceptibility. ERAP1 Genetic Variations Associated with HLA-B27 Interaction and Disease Severity of Syndesmophytes Formation in Taiwanese Ankylosing spondylitisNat. Nat. Genet. 2011, 43, 761–767. DOI: https://doi.org/10.1038/ng.873.
- Martin-Esteban, A.; Sanz-Bravo, A.; Guasp, P.; Barnea, E.; Admon, A.; Lopez de Castro, J. A. Separate Effects of the Ankylosing Spondylitis Associated ERAP1 and ERAP2 Aminopeptidases Determine the Influence of Their Combined Phenotype on the HLA-B*27 Peptidome. J. Autoimmun. 2017, 79, 28–38. DOI: https://doi.org/10.1016/j.jaut.2016.12.008.
- Zambrano-Zaragoza, J. F.; Agraz-Cibrian, J. M.; Gonzalez-Reyes, C.; Duran-Avelar Mde, J.; Vibanco-Perez, N. Ankylosing Spondylitis: From Cells to Genes. Int. J. Inflam. 2013, 2013, 501653. DOI: https://doi.org/10.1155/2013/501653.
- Chen, C.; Zhang, X. ERAP1 Variants Are Associated with Ankylosing Spondylitis in East Asian Population: A New Chinese Case-Control Study and Meta-Analysis of Published Series. Int. J. Immunogenet. 2015, 42, 168–173. DOI: https://doi.org/10.1111/iji.12196.
- Lee, Y. H.; Song, G. G. Associations between ERAP1 Polymorphisms and Susceptibility to Ankylosing Spondylitis: A meta-analysis. Clin. Rheumatol. 2016, 35, 2009–2015. DOI: https://doi.org/10.1007/s10067-016-3287-9.
- Vitulano, C.; Tedeschi, V.; Paladini, F.; Sorrentino, R.; Fiorillo, M. T. The Interplay between HLA-B27 and ERAP1/ERAP2 Aminopeptidases: From anti-Viral Protection to Spondyloarthritis. Clin. Exp. Immunol. 2017, 190, 281–290. DOI: https://doi.org/10.1111/cei.13020.