61
Views
5
CrossRef citations to date
0
Altmetric
Proceedings of the 12th International Symposium on Purine and Pyrimidine Metabolism in Man (PP07)

Polymorphisms of the TPMT Gene in the Czech Healthy Population and Patients with Inflammatory Bowel Disease

, , , , , , & show all
Pages 835-838 | Published online: 03 Jul 2008

REFERENCES

  • Tidd , D. M. and Paterson , A. R. 1974 . A biochemical mechanism for the delayed cytotoxic reaction of 6-mercaptopurine . Cancer Res. , 34 : 738 – 746 .
  • Weinshilboum , R. 2001 . Thiopurine pharmacogenetics: clinical and molecular studies of thiopurine methyltransferase . Drug Metab. Dispos. , 29 : 601 – 605 .
  • Schaeffeler , E. , Eichelbaum , M. , Reinisch , W. , Zanger , U. M. and Schwab , M. 2006 . Three novel thiopurine S-methyltransferase allelic variants (TPMT∗20, ∗21, ∗22) - association with decreased enzyme function . Hum Mutat. , 27 ( 9 ) : 976 – 984 .
  • Wei , H. , Zhou , S. , Li , C. , Zhang , J. , Wu , J. and Huang , M. 2005 . Phenotyping and genotyping studies of thiopurine S-methyltransferase in Kazaks . Pharm. Res. , 22 ( 10 ) : 1762 – 1766 .
  • Yates , C. R. , Krynetski , E. Y. , Loennechen , T. , Fessing , M. Y. Tai , H. L. 1997 . Molecular diagnosis of thiopurine S-methyltransferase deficiency: genetic basis for azathioprine and mercaptopurine intolerance . Ann. Intern. Med. , 126 : 608 – 614 .
  • Ameyaw , M. M. , Collie-Duguid , E. S. , Powrie , R. H. , Ofori-Adjei , D. and McLeod , H. L. 1999 . Thiopurine methyltransferase alleles in British and Ghanaian populations . Hum. Mol Genet. , 8 : 367 – 370 .
  • Haglund , S. , Lindqvist , M. , Almer , S. , Peterson , C. and Taipalensuu , J. 2004 . Pyrosequencing of TPMT alleles in a general Swedish population and in patients with inflammatory bowel disease . Clin. Chem. , 50 : 288 – 295 .
  • McLeod , H. L. , Pritchard , S. C. , Githang'a , J. , Indalo , A. Ameyaw , M. M. 1999 . Ethnic differences in thiopurine methyltransferase pharmacogenetics: evidence for allele specificity in Caucasian and Kenyan individuals . Pharmacogenetics , 9 : 773 – 776 .
  • Tai , H. L. , Krynetski , E. Y. , Yates , C. R. , Loennechen , T. Fessing , M. Y. 1996 . Thiopurine S-methyltransferase deficiency: two nucleotide transitions define the most prevalent mutant allele associated with loss of catalytic activity in Caucasians . Am. J. Hum. Genet. , 58 : 694 – 702 .
  • Schaeffeler , E. , Fischer , C. , Brockmeier , D. , Wernet , D. Moerike , K. 2004 . Comprehensive analysis of thiopurine S-methyltransferase phenotype-genotype correlation in a large population of German-Caucasians and identification of novel TPMT variants . Pharmacogenetics , 14 : 407 – 417 .
  • Toft , N. , Nygaard , U. , Gregers , J. and Schmiegelow , K. 2006 . Genetic analyses of thiopurine methyltransferase polymorphisms in Greenlandic and Danish populations . Acta Paediatr. , 95 : 1665 – 1667 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.