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OPEN PEER COMMENTARIES

The Duty to Support Learning Health Systems: A Broad Rather than a Narrow Interpretation

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REFERENCES

  • Eurpoean Centre for Diease Prevention and Control, 2020. COVID-19 situation update worldwide, as of 18 November 2020. Accessed November 18. https://www.ecdc.europa.eu/en/geographical-distribution-2019-ncov-cases.
  • Budrionis, A., and J. G. Bellika. 2016. The learning healthcare system: Where are we now? A systematic review. Journal of Biomedical Informatics 64:87–92. doi: 10.1016/j.jbi.2016.09.018.
  • Concato, J., N. Shah, and R. I. Horwitz. 2000. Randomized, controlled trials, observational studies, and the hierarchy of research designs. New England Journal of Medicine 342:1887–92.
  • Faden, R. R., N. E. Kass, S. N. Goodman, P. Pronovost, S. Tunis, and T. L. Beauchamp. 2013. An ethics framework for a learning health care system: A departure from traditional research ethics and clinical ethics. The Hastings Center Report 43 (s1):S16–S27. doi: 10.1002/hast.134.
  • Garrow, J. S. 2007. What to do about CAM: How much of orthodox medicine is evidence based? BMJ (Clinical Research ed.) 335 (7627):951. doi: 10.1136/bmj.39388.393970.1F.
  • Grobbee, D. E., and A. W. Hoes. 2014. Clinical epidemiology: Principles, methods, and applications for clinical research. Burlington, MA: Jones & Bartlett Publishers.
  • Halperin, J. L., G. N. Levine, S. M. Al-Khatib, K .K. Birtcher, B. Bozkurt, R. G. Brindis, J. E. Cigarroa, L. H. Curtis, L. A. Fleisher, F. Gentile, S. Gidding, M. A. Hlatky, J. Ikonomidis, J. Joglar, S. J. Pressler, and D. N. Wijeysundera. 2016. Further Evolution of the ACC/AHA Clinical Practice Guideline Recommendation Classification System: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Journal of the American College of Cardiology 67 (13):1572–1574.
  • London, A. J. 2021. Self-defeating codes of medical ethics and how to fix them: Failures in COVID-19 Response and Beyond. The American Journal of Bioethics 21 (1): 4–13. doi: 10.1080/15265161.2020.1845854.
  • North, C. M., M. L. Dougan, and C. A. Sacks. 2020. Improving clinical trial enrollment — in the Covid-19 era and beyond. The New England Journal of Medicine 383 (15):1406–8. doi: 10.1056/NEJMp2019989.
  • Olsen, L., A. Dara, and J. Michael McGinnis. 2007. Institute of Medicine (US). Roundtable on evidence-based medicine. The learning healthcare system: Workshop summary. Washington: National Academies Publishers.
  • Pan, H., R. Peto, Q. A. Karim, M. Alejandria, A. M. Henao-Restrepo, C. H. García, M.-P. Kieny, et al. 2020. Repurposed antiviral drugs for COVID-19–interim WHO solidarity trial results. MedRxiv doi: 10.1101/2020.10.15.20209817.
  • Prasad, V., A. Cifu, and J. P. A. Ioannidis. 2012. Reversals of established medical practices: Evidence to abandon ship. JAMA 307 (1):37–8. doi: 10.1001/jama.2011.1960.
  • Relton, C., D. Torgerson, A. O'Cathain, and J. Nicholl. 2010. Rethinking pragmatic randomised controlled trials: Introducing the “cohort multiple randomised controlled trial” design. BMJ (Clinical Research ed.) 340:C1066.
  • World Health Organization. 2018. Consultation on monitored emergency use of unregistered and investigational interventions for ebola virus disease (EVD). https://www.who.int/emergencies/ebola/MEURI-Ebola.pdf?ua=1.
  • World Health Organization. 2020. “Solidarity” clinical trial for COVID-19 treatments. World Health Organization (WHO). Situation reports. Geneva: WHO. Accessed April 5, 2020. https://www.Who.Int/Emergencies/Diseases/Novel-Coronavirus-2019/Global-Research-on-Novel-Coronavirus-2019-Ncov/Solidarity-Clinical-Trial-for-Covid-19-Treatments.
  • Wouters, R. H. P., R. van der Graaf, E. E. Voest, and A. L. Bredenoord. 2020. Learning health care systems: Highly needed but challenging. Learning Health System 4 (3):e10211. doi: 10.1002/lrh2.10211.